Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Year 5-Psychiatry > passmed 16/03 > Flashcards

passmed 16/03 Flashcards

(62 cards)

Start Studying
1
Q

serotonin syndrome
causes?

A

hypertension
Muscle rigidity
Pupillary dilatation
tachycardia
Confusion
Agitation
Loss of muscle coordination
Diarrhoea
Shivering
Fever
Seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

side effects of antipsychotics

typical
D2 receptor antagonist

example?

A

extra pyramidal side effects
hyperprolactinaemia

haloperidol
chlorpromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

EPSE - extra pyramidal side effects

A

parkinsonism
acute dystonia
akathisia
tardive dyskinesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

when does tradive dyskinesia occur?

another word for this

A

common after sustained anti psychotic use

choreoatheiod movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

example of acute dystonia

A

sustained muscle contractions
torticollis
oculogyric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

why does galactorrhoea occur in anti psychotic use?

A

inhibition of dopaminergic tuberoinfundibular pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

triad of neuroleptic malignant syndrome

A

fever
altered mental state
muscle rigidity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

which antipsychotic reduces seizure threshold

A

clozapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

side effects of clozapine

A

neutropenia
agranulocytosis
reduced seizure theshold and
myocarditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

olanzapine associated with?

A

dyslipidaemia
weight gain
diabetes
sedation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

notable side effect of quetiapine

A

postural hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

agranulocytosis

A

when neutrophil count is below 100 neutrophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the screening test for OCD

A

Yale brown Obsessive compulsive scale
Y-BOCS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

venlafaxine is a?

A

SNRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

is clozapine doses are missed how to take t again?

A

re-titrate and give slowly if missed over 48 hours

side effects can be worse after 48 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

management of acute alcohol withdrawal

A

chlordiazepoxide / diazepam [long acting benzo]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

bulimia nervosa

physical signs

A

metabolic alkalosis woith a low chloride

loss of HCL from stomach
hypokalaemia on ECG

palpitations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

common features of ptsd?

A

re experiencing - flashbacks
avoidance - avoiding people / situations
hyperarousal : hypervigilence / sleep problems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

management of tardive dyskinesia?

A

tetrabenazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what effect does bulimia have on teeth?

A

short rounded teeth / erosion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

korsakoff and wernicke what differentiates them?

A

anterograde amnesia
retrograde amnesia
confabulation

its a complication of wernicke but memory is also impacted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

antipsychotics in elderly patients increase risk of ?

A

stroke and
vte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

how can depression and dementia be differentiated?

A

rapid onset
and short history ois depression
alongside biological features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

if patient cannot tolerate second line treatment for GAD what can you offer?

A

pregabalin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
2nd line management of GAD
alternative SSRI (to sertraline) or Start SNRI ( duloxetine / venlafaxine)
26
sertraline can cause what kind of electrolyte imbalance
hyponatraemia
27
management of mania/hypomania in patients taking antidepressants
antidepressants can cause / trigger a manic episode - stop antidepressant and start a second generation antipsychotic
28
what effect can lorazepam have on memory?
can cause anterograde amnesia
29
lithium ecg changes?
t wave inversion / flattening
30
how often should lithium levels be checked once dose is set?
3 monthly
31
anorexia nervosa G's and C;s raised
growth hormone glucose salivary glands cortisol cholesterol carotinemia
32
ECT is indicated when?
catatonia prolonged / severe manic episode severe depression that is life threatening
33
what effect can smoking cessation have on clozapine?
smoking cessation can cause a rise in clozapine levels tar in cigarettes induce CYP450 increases clozapine metabolism so reduced levels when smoking is ceased clozapine levels go up
34
SSRI discontinution syndrome
dizziness electric shock sensations anxiety
35
TRicyclic overdose
hypotension drowsiness seizures
36
opiate withdrawal
anxiety sweating gastrointestinal symptoms
37
alcohol withdrawal
anxiety tremor sweating
38
erotomania - de clerambault is a type of
delusional disorder
39
most important impairment of ECT?
memory loss retrograde amnesia - prior to insult
40
immediate s/e of ECT
drowsy confused headache nausea aching muscles loss of appetite
41
long term s/e of ECT
apathy anhedonia diff concentrating loss of emotional responses difficulty learning new information
42
absolute contraindictaion for ECT
raised ICP
43
when is ECt useful?
catatonia - severe depression refractory to medication
44
what is somatisation disorder?
excess distress due to symptoms w no identifiable cause
45
what is difference between illness anxiety disorder and somatisation
somatisation - symptoms physically present as opposed to a belief of underlying illness
46
tardive dyskinesia is defined as
late onset involuntary movements that typically affect orofacial muscles > grimacing, tongue protrusion and lip smacking
47
parkinsonism why does it occur with antipsychotics?
resting tremor bradykinesia rigidity postural instability dopamine-blocking effects of the medication in basal ganglia
48
lithium toxicity manifets how long after?
6-18 months it can cause hypothyroidism
49
capgras syndrome
irrational delusion of misidentification where patients believe that a relative or friend has been replaced by an identical impostor
50
TCA's
amitriptyline clomipramine dosulepin trazodone
51
how does mirtazapine work?
blocks alpha-adrenegric receptors sedative increases appetite
52
switching antidepressants citalopram etc to another SSRI
first is withdrawn before alternative is started
53
fluoxetine to another SSRI
withdraw then leave a gap of 4-7 days as it has a long half life
54
SSRI to a tca
cross-taper
55
GAD mx second?
alternative SSRI / SNRI
56
PPI is indictaed when giving ssri
NSAID +SSRI - PPI
57
long term atypical antipsychotic use causes dysregulation of what?
glucose diabetes > polyuria / polydipsia
58
atypical antipsychotics effect on GI
antagonise acetylcholine M1 receptors > constipation as action of ach is blocked
59
hoover sign?
differentiates organic - non organic pressure felt in under the paralysed leg when lifting the non paralysed leg under pressure due to the contralateral hip extension
60
severe OCD
SSRI and CBT
61
z drugs s/e
they act on the α2-subunit of the GABA receptor. increase risk of falls
62

Year 5-Psychiatry (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions