Passmed Key Concepts Flashcards

(38 cards)

1
Q

Which SSRI leads to QT elongation and torsades de pointes?

A

Citalopram

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2
Q

What is first-line treatment for menorrhagia?

A

Tranexamic acid

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3
Q

What is the definition of pre-eclampsia?

A

New-onset BP >140/90mmHg after 20w AND proteinuria/organ dysfunction

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4
Q

When can hormonal contraception be started again after using levonorgestrel for emergency contraception?

A

Immediately

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5
Q

How do you manage a pregnant woman with previous VTE history?

A

Prophylactic LMWH throughout pregnancy until 6 weeks postnatal

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6
Q

What does an older woman with a labial lump + inguinal lymphadenopathy suggest?

A

Vulval carcinoma

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7
Q

What should you do if you are presented with a case of FGM in someone under 18?

A

Report it to the police

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8
Q

How does ovarian cancer initially spread?

A

Locally into pelvic area

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9
Q

What advice should you give about contraception to patients assigned female at birth?

A

Can’t use any contraceptions with oestrogen in if they’re undergoing testosterone therapy as antagonises it

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10
Q

What does a complete hydatidiform mole (pregnancy) look like on ultrasound?

A

‘snow storm’ appearance on ultrasound scan

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11
Q

How are pregnant women >20w who present within 24 hrs of a rash appearing (chickenpox) treated?

A

Oral aciclovir

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12
Q

What sign is ovarian torsion associated with on ultrasound?

A

Whirlpool sign

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13
Q

For transgender males, does testosterone therapy provide protection against pregnancy and what effects can it have on the pregnancy if it doesn’t?

A

No it doesn’t

Teratogenic effects

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14
Q

What is an important risk factor for hyperemesis gravidarum?

A

Multiple pregnancy

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15
Q

What is the cervical screening timeline?

A
25y - first invite
25-49 - every 3 years
50-64 - every 5 years
65+ not offered
delay 3 months post-partum unless missed previous or previous abnormal
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16
Q

What treatment is first-line for painful periods that are otherwise normal?

A

NSAIDs - inhibit prostaglandin synthesis (one of main causes of dysmenorrhoea pains)

17
Q

What is the symphysis-fundal height, where is it measured, and what should you do if it’s abnormal?

A

Measure to establish whether small for dates, should be 1-2cm from the gestational age in weeks e.g. 24 weeks should have a SFH of 22-26cm.
Measured from top of pubic bone to top of uterus in cm.
Get ultrasound to confirm if foetus is small for gestational age.

18
Q

What is the main investigation of suspected placenta praevia?

A

Transvaginal ultrasound

19
Q

What are 2 common long-term complications of vaginal hysterectomy with antero-posterior repair?

A

Enterocele

Vaginal vault prolapse

20
Q

Which emergency contraception should be used with caution in patients with severe asthma?

21
Q

What is the first step after a woman presents concerned about reduced foetal movements?

A

Handheld Doppler to confirm foetal heartbeat

22
Q

How long does it take each contraceptive type to be effective after administration?

A

Instant - IUD
2 days - progesterone-only pill
7 days - combined oral contraceptive, injection, implant, IUS

23
Q

What is a major risk factor for cord prolapse?

A

Artificial rupture of membranes

24
Q

What is a potential complication of ovulation induction?

A

Ovarian hyperstimulation syndrome

25
What is a typical presentation of ovarian hyperstimulation syndrome?
Acute presentation of hours-ago onset abdominal pain + bloating that has been increasing. On exam abdo tenderness + ascites. Hx of IVF treatment (ovulation induction)
26
What is a major contraindication for injectable progesterone contraceptives?
Current breast cancer
27
What scale is used to screen for postnatal depression?
The Edinburgh Scale
28
How should you manage premenstrual syndrome?
SSRIs (fluoxetine) either continuously or during the luteal phase
29
What is the first-line treatment for a <35mm ectopic pregnancy with no heartbeat?
Methotrexate (interferes with DNA synthesis and disrupts cell multiplication so pregnancy doesn't develop)
30
What is the definition of pregnancy-induced hypertension? (and what features does it lack that differs from pre-eclampsia?)
>140/>90 mmHg after 20w | No proteinuria or oedema
31
How do you manage pregnancy-induced hypertension?
Oral labetalol
32
When must methotrexate be stopped for males AND females before conception?
At least 6 months in both men and women
33
What is the management if at the time of diagnosis of gestational diabetes, the fasting glucose is >7mmol/L?
Insulin (with or without metformin) should be started immediately
34
How is PPROM (preterm premature rupture of membranes) investigated and why?
Sterile speculum exam | Then, if no fluid in posterior vaginal vault, use US to assess for oligohydramnios
35
How are perineal tears classified after birth?
1st degree - tear within vaginal mucosa only 2nd degree - tear into subcutaneous tissue (submucosa) 3rd degree - laceration extends into external anal sphincter 4th degree - laceration extends through external anal sphincter into rectal mucosa
36
What is the key clinical feature of placenta praevia?
Painless bleeding after 24w
37
How long are healthy couples expected to take to conceive and when would investigations be started?
Up to 1 year, investigations only started after 1 year of regular attempts to conceive
38
What are 3 important causes of placental abruption and what are their distinguishing features?
Placental abruption - abdominal pain + vaginal bleeding HELLP (Haemolysis, Elevated Liver enzymes, Low Platelets) syndrome - Anaemia or low platelets seen in blood results Cocaine use - Dilated pupils + hyperreflexia Pre-eclampsia - absence of the other 2 and fit of clinical scenario