Past paper questions Flashcards by Aureliah K

Which Abx inhibit protein synthesis

Macrolides - Erythromycin
Aminoglyclaides - Gentamicin
Tetracyclines - Tetracycline + Doxycycline

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Which Abx inhibit cell wall synthesis

Cephalosporins - Ceftriaxone
Penicillins
Vancomycin

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Which Abx inhibit DNA replication

Ciprofloaxcin

Levofloxacin

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What determines haemodynamic compromise

Systolic BP < 90

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Hyperkalaemia ECG

Tall T waves
Prolonged PR interval
Wide QRS
Absent P

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Hypokalaemia ECG

U waves
Inverted T waves
Prolonged PR
ST depression

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Features of carinoid syndrome

Flushing
Diarrhoea
Cardiac involvement

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What can cause hyperglycaemia in Diabetics

Thiazides

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Presentation of PCRV

Thrombosis 
headache 
dizzy 
visual disturbance 
vertigo 
tinnitus 
IC

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Amitryptiline A/E

Dry mouth
confusion
urinary retention
blurring vision

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Myeloma presentation

C - Hypercalcaemia
R - Renal imparement (Free light chains)
A - Anaemia + Pancytopenia
B - Lytic bone lesions / Fractures / Vertebral collapse

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Blood glucose measurements

Fasting > 5.5
Pre diabetes (5.6 - 7)
Random > 11
HbA1c > 48

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6 in 1 vaccination

Diptheria 
tetanus 
polio 
Hep B 
Haemophilius influenzae B 
Whooping cough

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Myeloproliferative disorders

cells increased
assosciated mutation

Haemopoetic stem cells –> Primary myelofibrosis

Erythroid cells –> PCV

Megakarocyte –> Essental thrombocythaemia

JAK2 MUTATION

Has the potential to cause AML

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What are the Ab for Hashimotos thyroditis

Anti - thyroperoxidase Ab

Anti - thyroglobulin Ab

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Causes of primary hypothyroid

Hashimotos
Iodine deficiency
Drug induced - lithium
Tx for hyperthyroidism

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SSRI’s adverse effects

GI upset 
weight disturbance 
Hyponatraemia 
suicidal thoughts 
Prolong QT - Citalopram 
Increased risk of bleeding

Gastric ulcers

Pain when eating

Pain occurs 30mins - 1hr after a meal

Duodenal ulcer

Pain relieved by eating
Occurs 2-3hrs after meal
Night pain
Weight gain

TTP Presentation

Haemolytic anaemia 
decreased platelts 
AKI 
Headache / palsies / seizure - Neuro sx
Fever 
Schistocytes

Exacerbation of COPD common organisms

Haemophilius Influenzae

2. Strep pneumonia

Causes of hypoadrenalism

Primary
Secondary

Addisons
Surgery
Infection
Loss of blood flow
Long term steroid usage

Gold standard Ix for Acromegaly

Oral glucose tolerance test

Carcinoid syndrome

secretion
presentation
tx

Insulin / ACTH / Serotonin / Bradykinin

Bronchoconstriction
Hyperglycaemia

SST analogue

Prophlaxis for sickle cell crisis

Hydroxcarbamide

Tx for sideroblastic anaemia

Pyridoxine

Acute liver failure charecteristics

No previous liver disease INR > 1.5 Onset < 26wks Mental alteration - HE

Inheritance pattern for Haemophillia

X - lined recessive

COPD Tx pathway

SABA/SAMA Asthma respose - LABA + ICS NO Asthma response - LABA + LAMA Oral theophlinne Long term O2

Spinal cord compression presentation

UMN Sx - Below level of lesion LMN Sx - At level of lesion

Describe Strep Pneumonia

Gram +ve diplococcus

Sensitivity

Proportion of pwople with a disease who test positive

Speicific

Proportion of people who don't have the disease who test negative

+ve predicted value

Proportion of people who test +ve who have the condition

-ve predicted value

Proportion of people who test ive who don't have the condition

Primary prevention

Decrease initial occurence NHS Health check Stain use Immunisation

Secondary prevention

Tx disease to halt progression + prevent long term problems | Anti platelts post MI

Tertiary prevention

Reduce impact of the disease + improve QOL

Complicate UTI

``` Men children Pregnant woman Recurrent UTI Structural abnormality ```

WPWS ECG

Short PR interval wide QRS Delta wave