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Flashcards in Patel Deck (17)
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1

Strep A

Abrupt onset of sore throat
Tonsillopharyngeal erythema and exudate
Tender, enlarged anterior cervical LAD
Winter and early spring peak incidence
Dx: rapid test/ throat culture

2

Mono

Petechiae of palate
Tonsillar enlargement
Tender inguinal, axillary, or posterior auricular LAD
Splenomegaly
Adolescents and adults up to age 30

3

HSV

Gingivostomatitis and Pharyngitis together
Systemic illness with anorexia, & myalgia
Exudative, ulcerative lesions on pharynx.
Dx: culture from scrapping of the ulcer base.

4

EBV

Tender inguinal, axillary, or posterior, auricular LAD, Petechiae of palate, Tonsillar enlargement, Splenomegaly
Adolescents and adults up to age 30
Dx: Heterophile (“spot”)test, EBV anti-VCA IgM,IgG,IBNA test

5

HIV acute

symptoms, lasting up to 2 weeks
Painful mucocutaneous ulcerations on oral mucosa, penis, or anus
Nontender axillary, cervical, and
occipital LAD between 7 and 14 days
Nonpruritic, maculopapular
exanthem generalizing from face, chest to extremities—including palms and soles
Intravenous drug use, unprotected sexual intercourse, or other HIV exposure risks

6

Monospot

Positive for only acute infections

7

EBV and EA

Acute and reactivation positive

8

EBV and EBNA

Not positive in acute

9

EBV tx

Suportive care, prednisone for airway
No contact sports- 4 weeks
Regular sports- 3 weeks

10

M-trophic vs T-trophic HIV attachment

M- CCR5
T- CXCR4

11

Acute HIV

Long systemic flu like symptoms, rash, N/V

12

HIV testing

Eliza for gp120/140
Western for gp41/p24Ab for confirmation

13

HIV false negative

Early ART
Partial seroconversion in acute HIV
Advanced HIV with decline in p24 Ab.
Infection with HIV-2
Immunosuppresion due to malignancy or medications.

14

HIV false positives

Alloantibody from pregnancy, other collagen vascular disease
Receipt of experimental HIV vaccine

15

4th gen elisa

p24 Ag used

16

When to start ART

Pregnant
History of Aids defining illness
CD4 less than 350

17

Special HIV tests

HLA B5701 (If positive, do not give Abacavir)
CCR5 tropism assay