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Flashcards in Pathology Deck (42):
1

What's the difference between clinical and anatomic pathology?

Anatomic involves formerly alive tissue
Clinical pathology is done in a lab

2

Avenzoar

First physician known to have made postmortem dissections

3

Rudolf Virchow

Generally recognized to be the father of microscopic pathology

4

What's the difference between histology and cytology?

Histology looks more at tissue as an organized unit- still tries to preserve tissue structure
Cytology samples the cells and looks exclusively at type and cellular changes

5

What types of samples can be submitted for cytology and histology?

Cytology- smears
Histology- get parts of organs from an -ectomy
FNA biopsies get sent to cytology
Core bx is sent in formalin to pathology

6

What fixatives are used for histology?

Formalin
Alcohol

7

Well circumscribed

Fibroadenoma

8

Smoothly lobulated

Lipoma

9

Verrucous

Cutaneous condyloma

10

Papillary

Bladder tumors

11

Velvety

Nl gallbladder mucosa

12

Macule

Lentigo

13

Papule

Mole

14

Friable

Necrotic tumors

15

Viscous

Thick

16

Serosanguinous

Serum tinged with blood

17

Serous

Like serum (watery)

18

Mucinous

Thick and sticky or gelatinous

19

Tacky

Sticky

20

Suppurative

Green thick exudate

21

Hematoxylin

Stain for nuclear material

22

Eosin

Stain for cytoplasmic material

23

What does the pathologist do in the operating room?

If there is a surgery that involves multiple steps for the dx or the dx is made intraoperatively and possibly incidentally

24

Ziehl-Neelson

Mycobacteria

25

Congo red

Amyloid

26

Diff quick

Modified Giemsa stain

27

Giemsa

Lymphoproliferative disorders

28

Gram

Bacteria

29

Iron

Bone marrow

30

Mucicarmine

Adenocarcinomas

31

Periodic acid Schiff

Tumors with glycogen

32

Silver stain

Infectious dz

33

Toluidine blue

Mast cell dz

34

Trichrome

Liver

35

Wrights

Blood smears

36

What is the purpose of immunoperoxidase studies?

Classification of tumors
Prognostic factors
Predictive factors to guide specific therapy
Identification of extracellular material
Identification of infectious agents

37

Breast special studies

ER/PR
HER2/neu
GCDFP-15

38

Carcinoid tumor special studies

Chromogranin

39

Lung adenocarcinoma special study

TTF-1

40

Squamous cell carcinoma special studies

CK5/6
p63
p16
HPV

41

Thyroid special tests

Thyroglobulin

42

Melanoma special test

S100 protein