Flashcards in Pathophysiology Deck (19):
induced by medical treatments like chemo, radiation therapy, or surgical removal, beta blocker, chronic hormone replacement therapy
anterior pituitary growth hormone disorders
Acromegaly in adults, gigantism in children
increase in frontal sinuses, ring/shoe size, deepened voice and enlarged tongue. Treatment is GH replacement therapy.
hypoglycemia, growth 3%, dental delayed, thin hair and greater fat mass.
Adults have hypercholesterolemia, decreased bone density and body mass
Posterior pituitary of ADH diseases
hyposecretion- diabetes insipidus
hypersecretion- Syndrome of inappropriate ADH secretion, adrenal insufficency and Hypothyrodism
not enough ADH, too much water leaves the body, constant thirst and urination. Causes the 3 poly (polyuria, nocturia, high Na in blood)
more water, less Na, increase bp
primary failure of thyroid gland, secondary to a deficiency of TRH, TSH, or both, not enough iodine, cretinism, congenital, Hashimoto
Myxedema (in hypothyroid state)
thickening, non-pitting edematous changes in the soft tissues. coma is rare and life-threatening condition occurring in progression of Hypothyroidism. Treatment is thyroid hormone replacement
hypothyroid disorder, caused by untreated congenital thyroid hormone deficiency. Causes stunted growth mentally and physically, abnormal bone development myxedema- might have goiter
thyroid nodules for excess hormone secretion called hot nodules. It feels hot and might lose weight even though they are eating more. Solution is surgery removal, iodine ( radioactive) to shrink thyroid.
hyperthyroidism disorder, enlarged thyroid ( goiter) producing too much thyroid hormone, women are likely to get disease, runs in the family, only a small amount produces too much as most doesn't produce enough.
life threatening thyrotoxicosis, when excessive amounts of thyroid hormone is released. It triggers radioactive iodine therapy, emotional stress, uncontrolled diabetes. It increases heart rate, arrhythmia, CHF, temperature, extreme restless, agitation.
Treatment includes cooling with ice packs. BUT don't induce shivering
increase in calcitonin, bone deformity and fractures, Calcium stones in urinary tract.
Causes kidney stones, osteoporosis, dehydration, high serum calcium levels, decrease neuromuscular excitability
severe muscle tetany due to low calcium levels, too much claw like hands, numbness, cramps, spasms, seizures
causes anorexia, weight loss, salt wasting, diminished vascular tone, reduced cardiac output and low bp. Treatment is intravenous glucocorticoids and volume replacements
hypersecretion of corticosteroids, changes in carbs and protein metabolism, results in puffy moon shaped face
Adrenal medulla disorder, a tumor resulting in too much production of catecholamines.
causes hypertension, headache, tachycardia, tremor, nervousness