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560B Biochem of Nutr Additional Info > Pathways > Flashcards

Flashcards in Pathways Deck (29)
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1

In Glycogensis, glycogen is created from alpha-d-glucose.

True/False

True

2

Glycogensis occurs in the Mitochondria.

True/False

False...it occurs in the CYTOSOL

3

Glycogen is created to store glucose in a rapidly mobilizable form.

True/False

True

4

Most cells perform glycogenesis, but glycogen is mainly stored in:

1) Heart cells
2) Liver cells
3) Skeletal muscle cells
4) Kidney cells
5) All of the above
6) 2 and 3
7) 2 and 4

6) 2 and 3 ... liver and skeletal muscles

5

Liver stores of glycogen DECREASE in a well-fed state.

True of False

FALSE, they increase

6

Muscle glycogen is affected by short periods of fasting.

True/False

FALSE, it remains stable

7

Muscle glycogen is depleted after strenuous excercise.

True/False

True

8

The alpha(1->4) glycosidic linkages are made by which enzyme:

1) glycogen phosphorylase
2) glycogen synthase
3) glucose phosphorylase
4) glucose (1->4) sythase

2) glycogen synthase

9

Which pathway degrades glycogen?

1) glycolysis
2) glycogenolysis
3) glucoeneogenesis

2) glycogenolysis

10

Glycogenolysis occurs in the cytosol.
True/False

True

11

The same enzymes are used for glycogenesis and glycogenolysis.

True/False

FALSE

12

Glycogenolysis.
What is the primary product of breaking the alpha(1->4) bonds?

1) free glucose
2) glucose-1-phosphate
3) glucose-6-phosphate

2) glucose 1-phosphate

13

Glycogenolysis
What is the primary product of breaking the alpha(1->6) bonds?

1) free glucose
2) glucose-1-phosphate
3) glucose-6-phosphate

1) free glucose

14

Glycogenolysis.
Glycogen phosphorylase cleaves the alpha(1->4) bonds at the non-reducing end of the chain and requires which coenzyme?

1) B6
2) NADH
3) NADPH

1)B6

15

Glycogenolysis.
Phosphoglucomutase converts glucose 1-phosphate into glucose 6-phosphate in the cytosol.

True/False

True

16

Glycogenolysis.
In the LIVER, G6P is converted in the ER of the cell into glucose by which enzyme prior to release into the blood?

1) Glycogen phosphorylase
2) glycogen phosphatase
3) glucose-1-phosphatase
4) glucose-6-phosphatase

4) glucose -6-phosphatase

17

Glycogenolysis.
Glucose-6-phosphate in the muscle cell is dephosphorylated into glucose, just like in the liver.

True/False

FALSE. No G6-phosphatase in the muscle cell. the G6p goes right into glycolysis

18

Glycogenolysis.
Muscle cell glucose-6-phosphate enters into glycolysis to produce energy.

True/False

True

19

Glycogen synthase and glycogen phosphorylase are hormonally regulated to respond to the energy needs of the cell, so glycogenesis/glycogenolysis remain in a constant cycle.

True/False

TRUE

20

Glycolysis occurs in the mitochondria.

True/False

FALSE, in the cytosol

21

Glycolysis.
The end product of aerobic glycolysis is LACTATE.

True/False

FALSE...it's pyruvate

22

Glycolysis.
Lactate is the end product of.....

1) Anaerobic glycolysis
2) Aerobic glycolysis

1) anaerobic

23

In aerobic glycolysis, _________ is formed and later converted to ________ for entry into the TCA cycle.

1) lactate, pyruvate
2) pyruvate, lactate
3) lactate, Acetyl CoA
4) pyruvate, acetyl CoA

4) pyruvate, acetyl CoA

24

Hexosmonophosphate Shunt (HMP)/Pentose Phosphate Pathway (PPP) occur in the CYTOSOL.

True.False

TRUE

25

PPP creates 2 _______ for every glucose-6-p that enters in the oxidative phase,

1) NADH
2) NAD+
3) NADPH
4) NADP+

3) NADPH

26

The non-oxidative PPP phase creates ribose-5-phosphate for nucleotide synthesis.

True False

TRUE

27

Gluconeogenesis precursors:

1) Lactate
2) Pyruvate
3) glycerol
4) all of the above

4) all of the above

28

Gluconeogensis requires both cytosolic and mitochondrial enzymes.

True False

True

29

90% of gluconeogenesis occurse in the____, while 10$ occurs in the ______.

1) Heart, liver
2) Liver, kidney
3) kidney, liver
4) liver, brain

2) liver, kidney