Pediatrics Flashcards
(108 cards)
Sick neonate evaluation
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Congenital heart dis, what are the indications for intubation?
Profound dyspnea<br></br>Lethargy<br></br>Safety in transport<br></br>Anticipated apnea with prostaglandin infusion<br></br>
<p>What are three ductal-dependent cyanotic congenital heart lesions?</p>
<ol> <li>Tetralogy of Fallot,</li> <li>Tricuspid atresia,</li> <li>Pulmonic atresia or stenosis</li> </ol>
<ul> <li>Name three metabolic complications that patients are at risk for following drowning and/or accidental hypothermia:</li> </ul>
<ul> <li>Rhabdomyolysis,</li> <li>hyperkalemia,</li> <li>hypokalemia,</li> <li>hypoglycaemia,</li> <li>acidosis,</li> <li>DIC</li> </ul>
<ul> <li>Name three indications for ECMO in a patient with accidental hypothermia:</li> </ul>
<ol> <li>Prehospital cardiac instability (arrest),</li> <li>systolic BP <90mmHg,</li> <li>ventricular arrhythmias,</li> <li>core temperature < 28 degrees</li> </ol>
ED preparation for imminent labor:
<ul> <li>Move patient to resuscitation room,</li> <li>get ED delivery bundle (towels, kelly clamps, scissors, ring forceps, umbilical cord clamp, etc),</li> <li>prepare infant warmer,</li> <li>call for help</li> </ul>
Important questions to ask in NRP
Term or not<br></br>How many babies<br></br>Any complication during pregnancy<br></br>No of previous pregnancies<br></br>PMH
<ul> <li>You successfully deliver the baby after reducing a tight nuchal cord. Babe does not make any spontaneous cries and in fact seems a bit blue. What are the first 4 actions you would take in management?</li> </ul>
<ul> <li>Dry, stimulate, clear and position the airway, place in the warmer</li> </ul>
<ul> <li>Baby’s HR is 90bpm: what 3 interventions would you perform next?</li> </ul>
<ul> <li>PPV with BVM at 30-60 breaths/min,</li> <li>apply O2 sat probe,</li> <li>apply ECG monitors for accurate HR monitoring</li> </ul>
<ul> <li>At what point would chest compressions be started and at what rate?</li> </ul>
<ul> <li>HR < 60bpm, 3:1 with respirations;</li> <li>advanced airway strongly recommended</li> </ul>
NRP
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<ul> <li>What is the compression rate in children?</li> </ul>
<ul> <li>100-120/minute (same as adults)</li> </ul>
What is the recommended depth for compressions?
1/3 AP chest diameter (4cm infants, 5cm children)
What is the compression:ventilation ratio if no advanced airway is in place?
30:2 single rescuer, 15:2 two rescuer<br></br>If advanced airway: one breath every 2-3 seconds with continuous compressions <br></br>(NEW in 2020)
Peds assessment
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Name three features of the paediatric airway that differ from the adult <br></br>airway
smaller diameter, <br></br>smaller mandible, <br></br>large occiput, <br></br>large tongue, <br></br>anterior larynx, <br></br>long epiglottis, <br></br>angular vocal cords, <br></br>highly compliant trachea, <br></br>short trachea
What is the formula for estimating ET tube size?
<i>age/4+4 (uncuffed traditionally)</i><br></br>• AAP/PALS now recommends cuffed ET tubes to decrease the need <br></br>for tube changes
Name five non-infectious causes of stridor:
anaphylaxis, <br></br>foreign body, <br></br>subglottic hemangioma, <br></br>laryngomalacia, <br></br>tracheomalacia, <br></br>tumor
Croup, indicationd for admission
Ongoing increased WOB, <br></br>respiratory distress, or stridor 4hrs after steroid administration or repeated doses of <br></br>epinephrine
Epiglotis enlargement, name 2 non-infectious causes:
Steam inhalation<br></br>Caustic ingestion
Epiglotitis, common bacteria?
Strep pneumoniae<br></br>Strep pyogenes<br></br>Staph aureus<br></br>(Used to be H.influenzae type B)
What are indications on history of potentially severe <br></br>asthma exacerbation? Name five:
<p>Previous life threatening exacerbations, <br></br>previous ICU admission, <br></br>previous intubation, <br></br>deterioration while on steroids, <br></br>use of 2 or more salbutamol canisters in a month, <br></br>cardiopulmonary or psychiatric comorbidities</p>
What are the components of the PRAM score?
suprasternal indrawing, <br></br>scalene retractions, <br></br>wheeze, <br></br>air entry, <br></br>oxygen saturation
What medications are evidence based treatment for <br></br>severe asthma exacerbations? Name 3:
continuous nebulized salbutamol, three doses <br></br>nebulized atrovent, <br></br>IV steroids (methylprednisolone 1mg/kg or hydrocortisone 8mg/kg), <br></br>(IV fluid bolus), <br></br>IV MgSO4 (40-50mg/kg over 20min, beware BP)
helping?
IV salbutamol,
subdissociative dose ketamine,
heliox
exacerbation?
• persistently increased WOB
• beta agonist needed more frequently than q4h after 4-8hrs of treatment
• deterioration on systemic steroids
exacerbation?
• minimal or no respiratory distress
• improved air entry
• beta agonist use > q4h after 4-8 hours of treatment
hospitalizations? Vaccination status? History of recent fever?
Feeding? Making urine?
focal lung findings,
response to treatment is not as expected,
‘toxic’ appearance,
severe respiratory distress
ipratropium bromide (atrovent),
inhaled corticosteroids,
systemic corticosteroids,
antibiotics
history of prematurity,
underlying cardio-respiratory disease or immunodeficiency
need for supplemental O2 to maintain sats >90%,
cyanosis or history of apnea,
dehydration/poor fluid intake,
infant at high risk for severe disease,
family unable to cope
highly suggestive of true seizure activity? Name 3:
flickering eyelids,
dilated pupils,
blank stare,
lip smacking,
increased HR and BP during event,
post-ictal phase
associated with elevated temperature greater than 38,
single seizure in 24hrs,
generalized, lasts <15 min,
post-ictal with return to baseline (usually within 1 hour), and normal neurological exam
seizure lasting greater than 15 minutes, multiple seizures in 24 hours
ED) OR 2 or more consecutive seizures without a return to baseline in between
• What are your first steps in management? Name 5
airway assessment,
IV access,
cardiac monitors,
administration of benzodiazepines,
check the glucose and treat hypoglycemia
three different routes of administration you could use:
• intranasal midazolam 0.2mg/kg (max 5mg/nare)
• rectal diazepam 0.5mg/kg (max 20mg)
and IV midazolam. Name two medications other than
benzodiazepines you could administer next:
levetiracetam 60mg/kg/dose (1st);
phenytoin 20mg/kg (2nd);
phenobarbital 20mg/kg IV (2nd)
BRUE,
hyponatremia,
sepsis,
meningitis,
hypoglycaemia,
metabolic disorders,
trauma (accidental or non accidental),
bleeding disorder,
mass lesion
imaging? Name 3:
• Focal neurologic deficit
• VP shunt
• Neurocutaneous disorder
• Signs of elevated ICP
• History of trauma
• Immunocompromise
• Hypercoagulable state or bleeding disorder
• Malrotation, NEC, Hirschsprung
• Infant and toddler (1mo - 2yrs):
• Pyloric Stenosis, Intussusception
• Young child - older (2 yrs and up):
• Appendicitis, Obstruction
AOM,
pharyngitis,
DKA,
HSP,
testicular torsion
meningitis,
strep throat,
pneumonia,
myocarditis,
DKA
abnormal skin turgor, and
tachypnea
“some” dehydration
• Give single dose zofran and start rehydration after 15min
limp and his skin is pale with mottled extremities.
Name five non-infectious causes of this presentation:
heart disease,
hypovolemia,
endocrine emergency,
electrolyte abnormality,
inborn error of metabolism,
seizure,
toxin
(or IO), supplemental O2, check a sugar, get ECG
children?
D10W (5-10mL/kg in infants)
• Follow bolus with an infusion of D10W at maintenance
hepatomegaly,
poor feeding,
irritability,
hypoglycaemia,
respiratory distress,
vomiting
sepsis?
E.coli,
Listeria
low birth weight,
maternal GBS positive,
prolonged ruptured membranes
• IV gentamicin
• +/- IV cefotaxime (if suspected meningitis)
• Consider IV acyclovir
urine culture (catheter or clean catch sample)
blood cultures
CBC
CRP
procalcitonin
• No prior hospitalization
• No prolonged newborn nursery care
• WBC 5-15x109/L
• Bands less than 1.5x109/L
• Urine WBC < 5/HPF
• Urine negative for nitrites or leukocyte esterase
• CRP <20mg/L (if available)
• Procalcitonin < 0.5mcg/L (if available)
• No chronic illness
• No prior antibiotics
• No unexplained jaundice
• What 3 actions would you take if Noah met ALL low risk
criteria and you planned outpatient management?
treatment, and when to return
• Arrange followup within 24 hours
• Follow up all relevant culture results
uncomplicated pharyngitis,
URTI
thyrotoxicosis,
toxin ingestion,
intracranial hemorrhage,
neuroleptic malignant syndrome
WBC 15 or greater
tachycardia,
prolonged capillary refill,
cold extremities,
decreased urine output,
SpO2 < 94%,
mottled skin,
mental status changes (lethargy, confusion, inconsolability)
approx 60mL/kg total in first hour (*if PICU level care is available)
with suspected sepsis?
• IV Vancomycin if suspected meningitis 15mg/kg/dose
• Temperature 40 degrees or more
• Fever > 24 hours
• Suprapubic tenderness
• Jaundice
• Uncircumcised male
• Febrile, 2-24 months: Suggest use of UTI Calc to assist in determining risk of UTI and likelihood of UTI based on UA findings
• Febrile, >24 months: presence of urinary symptoms can be used as a criterion to determine need for UA and Cx
• In kids <2months: catheter or clean catch specimen
• In kids >2months: bag ok for screen, catheter or clean catch specimen for culture if leuk est or nitrite +, or leuks/bacteria on microscopic analysis
• Cough >10 days
• Persistently high temperature (>40) with no other explanation
• WBC 20 or greater
• Or if respiratory symptoms …
TB,
Tularemia,
Toxoplasmosis,
Cat Scratch Disease
lymphoma,
Kawasaki disease,
juvenile idiopathic arthritis,
drug fever,
diabetes insipidus,
inflammatory bowel disease,
periodic fever disorders
• What epidemiological factors would you consider on history? Name 3:
Travel history,
Geographic location,
Exposures (insects, plants, animals, sick contacts),
Medications,
Immunization status,
Immunologic status
• Distribution and progression of rash
• Timing of rash onset in relationship to fever
• Changes in morphology (ie papules to vesicles)
• Symptoms associated with the rash (pruritus, pain)
• Fever for 5 days plus four of:
• Bilateral conjunctivitis
• Oral mucous membrane changes
• Peripheral extremity changes (erythema, edema, or desquamation)
• Polymorphous rash
• Cervical adenopathy
• Treatment: IVIG, ASA
• Complications: coronary artery aneurysm, heart failure, MI, arrythmias
• What are risk factors for development of severe hyperbilirubinemia? Name five:
jaundice in first 24 hours,
ABO incompatibility,
hemolytic disease,
Prematurity
previous sibling received phototherapy,
cephalohematoma or significant bruising,
exclusive breastfeeding,
East Asian race
hepatitis,
biliary cholestasis,
alpha-1-antitrypsin deficiency
ABO incompatibility,
hereditary spherocytosis,
Gilbert’s syndrome,
G6P deficiency,
breastfeeding
• Child: young age, behavioural problems, chronic illness, disability, non-biologic, premature, low birth weight
• Family/environment: High unemployment, IPV, poverty, social isolation, lack of support
• Breaks: any fracture in a non-ambulatory child, femur fracture in an infant, humerus fracture in an infant, multiple fractures, healing fractures, skull fractures, metaphysical fractures (bucket handle), posterior rib fractures
• Bonks: head trauma - especially if skull fractures that are depressed, bilateral, complex, or open
• Burns : immersion scald, contact burns, patterns
• Bites: stereotypical pattern to human bites
ectopic pregnancy,
vasovagal,
seizure,
hypoglycemia,
anemia,
hypokalemia,
orthostatic,
substance use
family history of sudden cardiac death, chest pain/dyspnea,
no prodrome,
history of structural cardiac disease,
abnormal cardiovascular exam,
focal neurologic signs,
fever
your differential diagnosis:
• What ECG findings would you look for? Name 4:
• Long PR: AV conduction block
• Narrow, deep QRS: HCM
• Wide QRS and epsilon waves: arrhythmogenic RV hypertrophy
• Wide QRS: Vtach, WPW
• QT interval: long or short
• Also look for Brugada, ACS, myocarditis
1. TWI in R precordial leads
2. Epsilon waves (low amplitude notches after QRS and before T waves) in R precordial leads
What other historical factors are of specific value in this case? (5 marks)
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-Antecedent events such as seizure activity, feeding, recent URTI
-Duration of episode
-Resuscitative efforts provided by the parents (eg. mouth to mouth, stimulation)
-Any previous similar episodes?
-Pregnancy history (incl. maternal substance abuse)
-Gestational age at birth / prematurity
-Family history of SIDS
-Multiple bruises in various stages of healing
-Concerning bruise location (away from bony prominences)
-Patterned bruising
-Ligature marks
-Bites with an intercanine diameter >3cm (adult bite)
-Lacerations of frenulum / oral mucosa
-Burn patterns suggestive of immersion
-Cigarette burns
-Contact or caustic burns
-Congenital airway anomalies
-Seizures
-CNS lesions
-Hypoglycaemia
-Inborn errors of metabolism
-Congenital heart disease
-Dysrhythmias
-GERD
-Sepsis
-Meningoencephalitis
-Pneumonia
-UTI
-RSV/ Croup/ Pertussis
-Infantile botulism
-Accidental poisoning/ drug ingestion
-or Midazolam 0.2-0.5 mg/kg intranasal
-or midazolam 0.05-0.2 mg/kg IM
-or Diazepam 0.2-0.5 mg/kg IV/PR
Dilantin 20mg/kg IV (rate 1mg/kg per minute)
-or fosphenytoin 20 mg/kg IV (rate 1-3mg/kg per minute)
If refractory:
-Secure the airway
-Phenobarbital 20 mg/kg IV
-Anaphylaxis
-Angioedema
-Foreign body (airway or esophagus)
-Retropharyngeal abscess
-Bacterial tracheitis
-Epiglottitis
-Peritonsillar abscess
Features of impending respiratory failure:
-Tachycardia
-Tachypnea
-Hypoxia
-Significant distress or agitation
-Stridor at rest
-Marked retractions or intercostal/subcostal indrawing
-Tracheal tugging
-Decreased breath sounds
-Cyanosis or pallor
-Lethargy
-Tripoding/ sniffing position
-Drooling
-High fever
-Dysphagia
-Dysphonia
-Sore throat
-Observation in ER for improvement
-Parental education with discharge
-History of previous severe croup
-Known structural airway anomaly
-Significant degree of respiratory distress
-Poor response to initial therapy
-Inadequate fluid intake/ clinical dehydration
-Parental anxiety
-Living far from the hospital/ difficult access to return to hospital
-Uncertain diagnosis
-Repeat steroid dose (dexamethasone 0.6mg/kg PO or budesonide 2mg neb)
-Intubation
-Admission to hospital
-Pediatric consultation
-Focal neurologic deficits
-Seizures
-Sacral radiculopathy (includes urinary retention, constipation, paresthesia, and motor weakness)
-Acyclovir 10mg/kg IV q8hr
-Rifampin 600mg PO BID x2 days
-Ciprofloxacin 500mg PO x1 dose
-Ceftriaxone 250mg IM x1 dose
-Antibiotics: beta-lactams, sulfonamides, and nitrofurantoin
-Anticholinergic drugs/ antihistamines:
-Malignancy: leukemia, lymphoma
-Kawasaki's disease (½ mark for ‘vasculitis’)
-Systemic lupus erythematosus (SLE) (½ mark for ‘vasculitis’)
-Polyarteritis nodosa (½ mark for ‘vasculitis’)
-Juvenile idiopathic arthritis
-Inflammatory bowel disease: Crohn’s or Ulcerative Colitis
-Diabetes insipidus
-Familial Mediterranean fever
-Immunoglobulin deficiency (congenital or acquired)
-Non-accidental conditions/ Munchausens by proxy/ Factitious fever"
-Brucellosis
-Bartonellosis
-Leptospirosis
-Salmonellosis
-Toxoplasmosis
-Tularemia
-Tuberculosis/Mycobacterium
(no marks for conditions with localized pain, resp or urinary symptoms, etc)"
Gastroenteritis/ Hepatitis
Encephalitis/ deafness
Myocarditis/ pericarditis
Keratitis/ corneal ulceration
Encephalitis/Reye’s syndrome
Pneumonia/Pharyngitis/Otitis media
Gastroenteritis/ Hepatitis
Septicemia/disseminated VZV
Myocarditis
Glomerulonephritis
Thrombocytopenia/ Purpura
Estimation of Wt, HR, BP, RR (in Peds)
WEIGHT
- (Age x2) + 10
- < 1 yr: (Age (mo)/2) + 4
BLOOD PRESSURE
- Normal= (Age x2) + 90
- Lowest tolerable (i.e. decrease BP)= (Age x2) + 70
Elevated conjugated bilirubin
Rapidly rising TSB
TSB approaching exchange level
TSB not responding to phototherapy
Rising TSB > 3 wks
Sick-appearing neonate
- mnemonic Warm C‐R‐E‐A‐M
- Warm ‐ Fever >39°C for 5 days, PLUS 4 of the 5 following signs (or less in ‘atypical’ form of the disease):
- C ‐ Conjunctivitis, bilateral non‐exudative
- R ‐ Rash, polymorphic (e.g. urticarial, maculopapular) and on the body (not vesicular nor bullous)
- E – Edema or erythema of the hands, eventually leading to desquamation
- A ‐ Adenopathy with at least one anterior cervical lymph node >1.5cm (not generalized over the whole body)
- M – Mucosal involvement: fissured red lips, strawberry tongue
hepatomegaly,
poor feeding,
irritability,
hypoglycaemia,
respiratory distress,
vomiting