Peer-Teaching Flashcards

(61 cards)

1
Q
75yr old male
Sudden onset weakness in left arm, slurred speech and L sided facial droop
Resolved in 15 minutes
Smokes 10/day for 30 years
Most likely diagnosis
A

Transient Ischaemic Attack

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2
Q

Define Transient Ischaemic Attack

A

focal, sudden onset, neurological deficit lasting <24hrs, with complete clinical recovery

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3
Q

Causes of TIA

A

Thromboembolism from carotids
Cardioembolism
Hyperviscosity e.g. polycythaemia

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4
Q

What is amaurosis fugax

A

Emboli passes into retinal artery

A curtain descending over my field of vision’

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5
Q

Investigations of TIA

A

ABCD2- Risk score of a stroke
Carotid Doppler- stenosis
CT angiography- stenosis

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6
Q

Treatment of TIA

A
Modifiable Risk Factors- stop smoking/alcohol, exercise, diet
Aspirin immediately
Clopidogrel
Statin- simvastatin 
Treat BP- Beta Blocker or ARB
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7
Q
80yr old female
Sudden onset R arm weakness, sensory loss in R arm, difficulty speaking and swallowing
Present for >5hrs with no improvement
PMH: AF, Hypertension, Diabetes
Diagnosis?
A

Stroke

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8
Q

Define stroke

A

Rapid onset of neurological deficit caused by focal, cerebral, spinal or retinal INFARCTION

Rapidly developing signs of focal or global disturbance of cerebral functions, lasting for more than 24HRS or leading to death

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9
Q

Signs and symptoms of MCA stroke

A

Motor Weakness, Hemiplegia
Sensory disturbances
Receptive and Affective Aphasia

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10
Q

Signs and symptoms of ACA stroke

A

Frontal Lobe
Drowsiness
Logical thinking
Personality

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11
Q

Signs and symptoms of PCA stroke

A

Contralateral Hemianopia

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12
Q

Initial investigation of stroke

A

CT scan

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13
Q

Medical Treatment of ischaemic stroke

A

Throbolysis- IV Altepase

Aspirin for 2 wks then clopidogerol

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14
Q

Medical treatment of haemorrhagic stroke

A

Control BP- Beta Blocker/ ARB
Beriplex if warfarin related
Surgery- Clot evation

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15
Q

Conservative treatment of stroke

A

Rehabilitation- Physio, OT

Modifiable Risk Factors- Stop smoking/alcohol, exercise

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16
Q
50 Year old male
Local shopping
Sudden sharp pain- ‘Feels like he has been kicked in the back of the head’
Neck stiffness
Feels systemically fine
Diagnosis
A

Subarachnoid Haemorrhage

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17
Q

Give example of BV in extradural layer

A

Middle Meningeal Artery

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18
Q

Give example of BV in subdural layer

A

Bridging veins

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19
Q

Give example if BVs in subarachnoid layer

A

Circle of Willis

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20
Q

Main cause of subarachnoid haemorrhage

A

Berry aneurysm

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21
Q

What is a subarachnoid haemorrhage

A

Spontaneous bleed in subarachnoid space

Rupture of artery so raised ICP

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22
Q

What is result of raised ICP

A

Lower consciousness

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23
Q

Signs of subarachnoid haemorrhage

A

Kernigs and Bradzini sign

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24
Q

Ix of SAH

A

CT scan

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25
Tx of SAH
Neurosurgeon
26
Causes of subdural haemorrhage
RTA | Metastasis cause rupture
27
Pathophysiology of subdural haemorrhage
Rupture of bridging veins Few weeks/months later Haematoma formation -> Hyperosmotic so draws water from the brain Raised ICP and midline shift
28
Clinical presentation of SDH
Fluctuating consciousness | Headache
29
Ix of SDH
CT scan - Sickle shaped, crescent shaped collection of blood
30
Tx of SDH
Neurosurgeon - Irrigation | IV Mannitol
31
True or False: | Extradural haemorrhage is a medical emergency
True
32
Cause and pathology of extra dural haemorrhage
Head injury -> Fracture in temporal/parietal bone -> Rupture of the middle meningeal artery Rapid collection of blood in extradural space
33
Signs of extradural haemorrhage
Decrease consciousness, Signs of raised ICP
34
Complication of EDH
Tentornial herniation - death of respiratory arrest
35
Ix of EDH
CT scan- biconvex hypodense haematoma
36
Tx of EDH
Neurosurgery- irrigation, IV Mannitol
37
Clinical diagnosis of epilepsy
2 or more unprovoked seizures with >24hrs apart
38
Define seizure
The recurrent tendency to spontaneous, intermittent, abnormal electrical activity in part of the brain due caused by excessive, hypersynchronous neuronal discharges
39
Type of epilepsy seizures
Generalised | Partial/focal
40
What is Generalised seizure
Affects whole cortex with no localising features to one hemisphere
41
What is partial seizure
Focal onset with features referred to a lobe
42
Types of generalised seizures
``` Tonic-clonic Absence seizure Myoclonic Tonic Atonic ```
43
Describe generalised tonic-clonic seizure
No prodrome or aura. Tonic Phase- Rigidity -> Clonic Phase- Rhythmic muscle jerking (seconds to minutes). Post-ictal- Drowsiness, confusion and coma
44
Describe generalised absence seizure
Typically childhood, stops talking mid-sentence- carry on where left off
45
Describe generalised myoclonic seizure
Sudden isolated jerk of limb, face or trunk. May be thrown to the ground
46
Describe generalised tonic seizure
Sudden sustained stiffening of the body. | Not followed by jerking
47
Describe generalised atonic seizure
Sudden loss of muscle tone and cessation. Fall
48
Types of partial seizures
Depends on lobe affected
49
Purpose of temporal lobe
Memory, Emotion and Receptive speech
50
Describe partial seizure of temporal lobe
Aura- Deja-vu, auditory hallucinations, funny smells | Out of body experience, automatisms e.g. lip smacking, chewing, fiddling
51
Purpose of frontal lobe
Motor and Thought Processing
52
Describe partial seizure of frontal lobe
Jacksonian march - seizure “marches” up or down the motor homunculus starting in face or thumb Post-ictal Todd’s palsy - paralysis of limbs involved in seizure for several hour
53
Purpose of parietal lobe
Sensory disturbances
54
Describe partial seizure of parietal lobe
Tingling/numbness
55
What is Todd's palsy
Paralysis of limbs involved in seizure for several hour | Due to focal seizure of temporal lobe
56
Investigations of Epilepsy
EEG (electroencephalogram)
57
Tx of epilepsy: Emergency Generalised Partial
Emergency (Status Epilepticus)- IV Lorazepam Generalised- Sodium Valporate, Lamotrigine Partial/Focal- Carbamezapine
58
List the differences between dementia or delirium
``` Dementia: Onset - Insidious (months to years) Course - Progressive Duration - months to years Consciousness - Normal unless severe Causes - Disorder ``` ``` Delirium: Onset - Acute (hours to days) Course - Fluctuating Duration - hours to weeks Consciousness - Altered Causes - Stroke, Metabolic, Infective etc ```
59
What is dementia
A syndrome that causes memory loss, difficulties with thinking, problem-solving, language and ADL’s
60
Diagnosis of dementia
Clinical diagnosis | MMSE- <17/30 serious cognitive impairment
61
Treatment of dementia
Healthier Lifestyle Social Support Acetylcholinesterase Inhibitor (e.g Rivastigmine) Control CV Risk Factors