Pelvis and perineum Flashcards

1
Q

How is the pelvic cavity defined?

A

Coloured red. Abdominal and pelvic cavity is divided by the pelvic inlet. Note that its axis (red dotted line) is angled about 45 degrees, contrary to the axis of the abdominal cavity.

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2
Q

What does the pelvic girdle describe?

A

Concerns the bones of the pelvis and sacrum.

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3
Q

What are the two main functions of the pelvic girdle?

A

Hold the bodies weight and join to the lower limbs.

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4
Q

Label the parts of the pelvic girdle

A

1: Ala of sacrum
2: Iliac Crest
3: Iliac Fossa
4: Pelvic inlet
5: Sacrum
6: Ischial spine
7: Acetabulum
8: Pubic tubercle
9: Inferior pubic ramus
10: Pubic Arch
11: Pubic Synthesis
12: -
13: -
14: Obturator Foramen
15: Coccyx
16: Anterior Inferior Ililac Spine
17: Anterior sacral foramina
18: Anterior superior iliac spine
19: Sacro iliac joint
20: Base of sacrum

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5
Q

What are the two joints of the pelvic girdle?

A

Sacroiliac and pubic symphysis.

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6
Q

What is the true and false pelvis

A

The false pelvis contains the absominal cavity.

False is called the greater pelvis; true is the lesser pelvis and is the most important part of the pelvis.

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7
Q

Where are the superior and inferior pubic ligments situated?

A

Above and below the pubic synthesis respectively

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8
Q

What is the pelvic inlet and outlet?

A

Pelvic inlet is the superior aperture of the pelvis; pelvic outlet is a diamond shaped area – its boundaries are the pubic symphysis, right and left rami of the pubic arch, the sacrotuberous ligaments and tip of the coccyx.

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9
Q

What is the pubic angle? Alternative name? Differences between males and females?

A

AKA the subpubic angle, formed by the convergence of the inferior rami of the ischium and pubis on either side.
FEMALES: wide (usually larger than 90 degrees); MALES: narrower (usually smaller than 90 degrees).

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10
Q

What type of joint is the sacro-iliac joint?

A

Synovial.

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11
Q

What is the pubic symphysis made from? What is it specifically?

A

Cartilage – it is a secondary cartilaginous joint.

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12
Q

What are the three major bony regions of the hip bone?

A

ILIUM is the uppermost and largest part of the hip bone; ischium in blue; pubis in pink. These are THREE SEPARATE FUSED bones.

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13
Q

Where do the ilium, ischium and pubis fuse in the pelvis?

A

In the acetabular fossa.

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14
Q

What is the anatomy of the pelvic-femoral joint?

A

Acetabulum is the ‘socket’. The articular surface is a surface that makes normal direct contact with another skeletal structure as part of a synovial joint.

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15
Q

Where is the obturatur membrane

A

Thin fibrous sheet which almost completely closes the obturator foramen.

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16
Q

What does the sacro spinous ligment connect

A

Attatches ischium of pelvis to coccyx.

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17
Q

What is the pubic arch and sub pubic angle

A
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18
Q

What is the ischio-pubic ramus

A
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19
Q

What is the anterior longitudinal ligament ligaments

A
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20
Q

What is the greater sciatic notch/foramen

A
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21
Q

Lesser sciatic notch/foramen

A

D is the lesser sciatic notch/foramen. Formed by the sacrotuberous and sacrospinous ligament (add photo).

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22
Q

What are the differences between male and female pelvises? (x6)

A

[Note about photo – X = difference between symphysis pubis and anterior margin of acetabulum; Y = diameter of the acetabulum.]

Differences are based around the fact that female pelvises are designed for childbirth.

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23
Q

What does the lumbosacral ligament connect?

A

The lumbar and sacrum

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24
Q

Surface markings of the Kidney

A
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25
Q

What does the iliolumbar ligament connect

A

The iliac crest and lumbar 1

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26
Q

What does the anterior and posterior sacroiliac ligament connect

A

Sacrum and iliac crest

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27
Q

What does the sacrotuberous ligament connect

A

The sacrotuberous ligament is attached by its broad base to the posterior superior iliac spine, the posterior sacroiliac ligaments (with which it is partly blended), to the lower transverse sacral tubercles and the lateral margins of the lower sacrum and upper coccyx.

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28
Q

Where is the location of the transpyloric plane

A

Midway down the midclavicular line between clavicle and AIIS

or

Midway between pubic symphesis and sternal angle

runs at L1 level. T12 is halfway between scapula and highest point of iliac crest, then L1 is one vertebrae lower

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29
Q

How is palpation of Kidneys carried out?

A

“The subject should lie flat on a couch with knees and hips semi flexed, if necessary, to relax the abdominal wall muscles. The entire abdomen should be exposed. Only the lower poles of the kidneys can be palpated through the anterior abdominal wall just below the costal margins.

Bimanual palpation, using both hands, keep left hand under patients flank palm up-facing. Use right hand to palpate kidney anteriorally, and use index and third finger to ballott the kidney.

Shouldnt be able to feel in a healthy patient

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30
Q

Label the parts of the pelvic girdle

A

1: Ala of sacrum
2: Iliac Crest
3: Iliac Fossa
4: Pelvic inlet
5: Sacrum
6: Ischial spine
7: Acetabulum
8: Pubic tubercle
9: Inferior pubic ramus
10: Pubic Arch
11: Pubic Synthesis
12: -
13: -
14: Obturator Foramen
15: Coccyx
16: Anterior Inferior Ililac Spine
17: Anterior sacral foramina
18: Anterior superior iliac spine
19: Sacro iliac joint
20: Base of sacrum

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31
Q

What is the true and false pelvis

A

The false pelvis contains the absominal cavity

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32
Q

Where are the superior and inferior pubic ligments situated?

A

Above and below the pubic synthesis respectively

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33
Q

What is the pelvic inlet and what are its borders?

A
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34
Q

Where is the obturatur membrane

A
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35
Q

What does the sacro spinous ligment connect

A

Attatches ischium of pelvis to coccyx

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36
Q

What is the pubic arch and sub pubic angle

A
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37
Q

What is the ischio-pubic ramus

A
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38
Q

What is the anterior longitudinal ligament ligaments

A
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39
Q

What is the greater sciatic notch/foramen

A
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40
Q

Lesser sciatic notch/foramen

A

D is the lesser sciatic notch/foramen

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41
Q

What separates the greater and lesser sciatic notch/foramen?

A

Sacrospinous ligament.

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42
Q

What is the difference between male and female pelvis

A
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43
Q

What does the lumbosacral ligament connect?

A

The lumbar and sacrum

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44
Q

What does the iliolumbar ligament connect

A

The iliac crest and lumbar 1

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45
Q

What are the superior and inferior pubic ligaments?

A

.

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46
Q

What does the anterior and posterior sacroiliac ligament connect

A

Sacrum and iliac crest

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47
Q

What does the sacrotuberous ligament connect

A

The sacrotuberous ligament is attached by its broad base to the posterior superior iliac spine, the posterior sacroiliac ligaments (with which it is partly blended), to the lower transverse sacral tubercles and the lateral margins of the lower sacrum and upper coccyx.

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48
Q

What is the obturator internus muscle?

A

Most of the pelvic bone facing the pelvic cavity is covered by the obturator internus muscle and its fascia. Found at the anterior (internal) region of the lesser pelvis and arises from the obturator membrane, and the medial surface of the greater trochanter of femur. LINES THE PELVIC WALL.

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49
Q

What are the nerves associated with the pelvic wall?

A

Lumbar sacral plexus (seen in image) are the nerves that supply the lower limb, perineum and buttocks.

50
Q

What is the Piriformis muscle and its attachments?

A

Attached to the anterior part of the sacrum and across the superior sciatic foramen where it attaches to the medial surface of the greater trochanter of femur.

51
Q

What are the components of the pelvic diaphragm and purpose?

A

They form the floor of the pelvic cavity, support pelvic viscera, and elevate the anus.

Iliococcygeus, pubococcygeus and puborectalis collectively form the Levator ani muscle (they are three divisions of the same muscle). Coccygeus muscle is located posterior to this muscle. There’s also the obturator internus.

52
Q

What are the attachments of the coccygeus muscle?

A

Attached to sacrospinous ligament and ischial spine.

53
Q

What are the attachments of the Levator ani muscle?

A

Tendinous arch (of obturator internus fascia – an area of thickened arch) and interdigitate medially and form the anococcygeal ligament from both Levator ani muscles (from each side).

54
Q

Where is the location of the transpyloric plane

A

Midway down the midclavicular line between clavicle and AIIS

or

Midway between pubic symphesis and sternal angle

runs at L1 level. T12 is halfway between scapula and highest point of iliac crest, then L1 is one vertebrae lower

55
Q

Surface markings of the Kidney

A
56
Q

How is palpation of Kidneys carried out?

A

“The subject should lie flat on a couch with knees and hips semi flexed, if necessary, to relax the abdominal wall muscles. The entire abdomen should be exposed. Only the lower poles of the kidneys can be palpated through the anterior abdominal wall just below the costal margins.

Bimanual palpation, using both hands, keep left hand under patients flank palm up-facing. Use right hand to palpate kidney anteriorally, and use index and third finger to ballott the kidney.

Shouldnt be able to feel in a healthy patient

57
Q

How is the pelvic diaphragm – the Levator ani muscle innervated? Origin?

A

The pair of Levator ani muscles are skeletal, so are under voluntary control! They are supplied by a somatic nerve – the pubendal nerve (from S2, S3 and directly from S4 (derived from same place as the PNS S2,3,4 nerves, but are separate!)).

58
Q

How is the pelvis innervated autonomically?

A

Superior and inferior hypogastric plexuses.

59
Q

What is the perineum?

A

Defined as the surface between the pubic symphysis and coccyx (or area between the legs between the anus and scrotum/vagina.

60
Q

How is inflammation of a kidney felt? Palpation?

A

Inflammation of a kidney is most commonly felt as backache. Palpation of the appropriate parts of the posterior abdominal wall will reveal tenderness of the affected kidney.

61
Q

What is the cause of pain in the ureters commonly?

A

Pain from the ureters is most often caused by a kidney stone (renal calculus) entering the ureter. The efforts of the ureter to expel this through one of the three narrow points on the ureter (origin from renal pelvis, pelvic brim and entry into bladder) result in very severe pain called renal colic.

62
Q

What is the blood supply of the viscera of the pelvic cavity?

A

Internal iliac artery (a branch of the common iliac artery).

63
Q

How does the pelvic diaphragm look inferiorly? Two divisions of the pelvic diaphragm in inferior view?

A

Anterior half of the pelvic diaphragm is covered in perineal membrane (from which the genitals are also attached).

Anterior region is called the UROGENITAL TRIANGLE.
Posterior half has no perineal membrane. Posterior region is called the ANAL TRIANGLE.

64
Q

What are the divisions of the common iliac artery?

A

External and internal iliac arteries.

65
Q

What are the divisions of the internal iliac artery? (x2) And what does each division supply?

A

Posterior and anterior divisions.
ANTERIOR: visceral structures of the pelvic region e.g. bladder, uterus, genitalia, EXCEPT the ovaries.
POSTERIOR: muscles of the buttocks (gluteal muscles).

66
Q

How is the pelvic girdle orientated – landmarks that we should be familiar with?

A
  1. In the anatomical position, ASIS and pubic tubercles are in the SAME PLANE.
  2. Greater and lesser pelvises are continuous.
  3. Axis of the pelvic cavity is approximately 45 degrees.
67
Q

What are the anatomical relations of the anal and urogenital triangles to the pelvic girdle?

A

Photo.

68
Q

What is fascia?

A

A sheet or band of connective tissue that attaches and separates muscles and other internal organs.

69
Q

What does parietal mean?

A

Associated with a body wall or a body cavity.

70
Q

What happens to the peritoneum in the pelvic cavity?

A
  • Parietal peritoneum continues into the pelvic cavity but does not reach the pelvic floor.
  • Pelvic viscera are therefore only PARTIALLY covered by peritoneum (except the uterine tubes which are completely covered).
  • Several folds and pouches are formed.

[NOTE that peritoneum in the photo is indicated in blue].

71
Q

Where is pelvic fascia found?

A

Pelvic fascia is found in the spaces between the peritoneum and the pelvic wall not occupied by viscera. Pelvic fascia is indicated by yellow in the photo and has parietal (green line) and visceral (orange line) components.

72
Q

What are pelvic fascia ‘condensations’?

A

Fascia of the muscles forming the pelvic floor may be thickened to form ‘ligaments’ which support viscera.

73
Q

What are the two make-ups of ligaments in the pelvic region?

A

Ligaments can be thickening of the peritoneum, or condensation of the pelvic fascia.

74
Q

What are the contents of the male pelvic cavity?

A
  • Ureter, bladder, urethra;
  • prostate, ductus deferens, seminal vesicles, bulbourethral glands;
  • rectum;
  • some of the abdominal GI tract spills into the greater pelvis (caecum, appendix, parts of the sigmoid colon and ileum);
  • vessels, nerves and lymphatics.

NOTE the two bends of the urethra (1 and 2) in the photo – only number 2 can be straightened.

75
Q

What is the ductus deferens?

A

AKA the vas deferens: Small muscular tube in the male reproductive system that carries sperm from the epididymis (emerging tube of the testicle) to the ejaculatory duct (created when the seminal vesicle’s duct merges with the ductus deferens).

76
Q

What are seminal vesicles?

A

AKA vesicular glands: a pair of simple tubular glands posteroinferior to the urinary bladder that secrete fluid that partly composes the semen.

77
Q

What are bulbourethral glands?

A

Located beneath the prostate that add fluids to semen during ejaculation.

78
Q

What structures in the male pelvis can be felt by a digital rectal examination (DRE) of a healthy man?

A

Feel enlarged rectum, diagnosis of appendicitis, you can also feel the bladder.

79
Q

What is the anatomical position of the prostate gland?

A

Surrounds the 1st (prostatic) part of the urethra.

80
Q

What is the anatomical position of the ductus deferens?

A

From the testes, passes through the inguinal canal, then over and behind the URETER to enter the URETHRA through the prostate.

81
Q

What is the anatomical position of the seminal vesicles?

A

Posteroinferior to the bladder and opens into the ductus deferens between the AMPULLA of VAS DEFERENS and EJACUALTORY DUCT.

82
Q

What is the precaution that must be considered when inserting a urinary catheter?

A

The 90 degrees bend of the urethra as it passes from the perineum to the pelvis.

83
Q

What are the corpus cavernosa?

A

Sponge-like regions of erectile tissue which contain most of the blood in the penis during an erection.

84
Q

What proportion of the semen is secreted from: the seminal vesicles and the prostate?

A

60% from seminal vesicles, 40% from prostate.

85
Q

What is the anatomy of the prostate urethra?

A

Where urinary and reproductive tracts meet.

INTERNAL URETHRAL SPHINCTER: smooth muscle well organised.

EXTERNAL URETHRAL SPHINCTER: skeletal muscle.

PROSTATIC UTRICLE: small indentation that is the homologue (shared ancestry between a pair of structures) of the uterus and controls opening of the ejaculatory ducts.

86
Q

How is the internal urethral sphincter controlled?

A

Closed during ejaculation by SYMPATHETIC stimulus. Parasympathetic stimulation relaxes the sphincter.

87
Q

What is the structure of the male urethra?

A

Preprostatic part, prostatic, membranous and spongy part of the urethra.

88
Q

What are the three areas of narrowing/obstruction that you should be concerned about in the navigation of a catheter?

A
  1. Tip of the urethral catheter can become lodged in the prostatic utricle.
  2. The external urethral orifice.
  3. 90 degrees bend at the perineal membrane.
89
Q

What is the blood supply of the prostate?

A

Prostatic branch of the inferior vesical artery, which is a branch of the internal iliac artery.

90
Q

What is the blood supply of the bladder and ductus deferens?

A

Superior and inferior vesical artery, which is a branch of the internal iliac artery.

91
Q

What is the blood supply of the testes?

A

Testicular artery arising from the abdominal aorta, not from the internal iliac artery.

92
Q

What are the bony landmarks of the perineum? Shape?

A

Diamond-shaped area between pubic symphysis, ischial tuberosities and coccyx.

93
Q

What is the living anatomy of the perineum?

A

Diamond-shaped area between the thighs when the person lies on the back with thighs flexed and abducted.

94
Q

What are the two triangles of the perineum?

A

Already mentioned – anterior, urogenital triangle and posterior, anal triangle.

95
Q

What is the ischio-anal fossa? Function?

A

Ischio-anal fossae = fat-filled spaces separating anal canal and levator ani from the pelvic walls, found in the anal triangle of the PERINEUM. They allow recto-anal and vaginal expansion.

96
Q

What is found in the lateral wall of the ischio-anal fossae?

A

In their lateral wall is the pudendal neuro-vascular bundle supplying the perineum including the lower rectum.

97
Q

What is the vasculature that crosses the ischio-anal fossae? Clinical implication in females during childbirth?

A

Inferior rectal vessels and nerves cross the fossa. They may be cut if an episiotomy (surgical cut made at the opening of the vagina during childbirth) is carelessly placed. These vessels and nerves arise from the pudendal canal, a fibrous sheath on the lateral wall of the fossa within which the pudendal nerve and the internal pudendal vessels run forward from the posterior pelvis to the anterior perineum.

98
Q

What is the two parts of the anterior compartment of the perineum?

A

Divided into superficial and deep parts (or pouches) by the perineal membrane.

  • PERINEAL MEMBRANE: thick triangular fascial structure attached to the pubic arch. Posteriorly has a free margin, and anteriorly there is a small gap (where the urethra is?).
  • DEEP PERINEAL SPACE/POUCH: above the perineal membrane and below the fascia of the pelvic diaphragm.
  • SUPERFICIAL PERINEAL SPACE/POUCH: is between the perineal membrane and perineal fascia, and the subcutaneous fat of the skin.
99
Q

What is the nature of the superficial and deep perineal spaces?

A

They are POTENTIAL SPACES, and only become REAL spaces when for example, fluid leaks into them. Remember, these spaces are only found in the anterior perineal triangle, where there is a perineal membrane.

100
Q

What are the structures of the superficial perineum in males?

A
  • CRUS OF PENIS: the first 1/4th portion of the corpora cavernosa, where the sponge-like structures diverge.
  • PERINEAL BODY: is the central tendon which forms the junction between the two perineal triangles – found between the bulb of the penis and the anus.
  • PERINEAL MEMBRANE: erectile tissues and associated skeletal muscle are associated with the perineal membrane.
  • CORPUS SPONGIOSUM: median erectile tissue mass – bulb of penis.
  • CORPORA CAVERNOSA: lateral erectile tissue masses attached to ischiopubic rami.
  • BOTH: the median and lateral erectile tissues meet to form the shaft and head (GLANS OF PENIS) of the penis (or clitoris in females).
  • The erectile tissue within perineum is surrounded by SKELETAL MUSCLE.
101
Q

What are the SKELETAL muscles associated with the superficial perineal structures in men? (x3)

A

Remember, these are all SUPERFICIAL muscles of the perineum. They are skeletal, and contract during ejaculation.

  • ISCHIOCAVERNOSUS MUSCLE: stabilisation of the erect penis – associated with the proximal part of the corpus cavernosum. It COVERS the corpora cavernosa crura (legs).
  • BULBOSPONGIOUSUS MUSCLE: covers the bulb of the penis (bulb of the corpus spongiosum).
  • SUPERFICIAL TRANSVERSE PERINEAL MUSCLE: includes the muscle under the perineal membrane, and all converge onto the perineal body – the central perineal tendon.
102
Q

What are the structures of the deep perineum in males?

A

Photo.

103
Q

Difference in structures in the anal triangle between males and females?

A

THEY ARE THE SAME.

104
Q

What are the structures and anatomy of the anal triangle of the perineum?

A

Photo.

105
Q

What is the blood supply of the rectum?

A

Receives one pair of arteries from the INFERIOR MESENTERIC ARTERY (superior rectal artery) and two pairs from the INTERNAL ILIAC ARTERY (middle and inferior rectal artery).

106
Q

What is the venous drainage of the rectum?

A

Venous drainage is similar to arterial supply; thus, there is an important portal-systemic venous anastomoses around the lower rectum and anal canal – because one goes to the portal, and one goes to the systemic circulation.

107
Q

What is the anatomy of the spermatic cord?

A

OUTSIDE –> INSIDE: external spermatic fascia, cremasteric fascia, internal spermatic fascia (from the external oblique, internal oblique and transversalis fascia of the anterior abdominal wall respectively).

From the deep inguinal ring of the inguinal canal.

108
Q

What is the anatomy of the testis?

A

Spermatozoa are produced in the seminiferous tubules and migrate to the rete testis and efferent ductules. Then, they emerge at the head, body and tail of epididymis and travel inferiorly into the vas deferens.

109
Q

Where does the testicular artery originate?

A

Below the renal artery, from the abdominal aorta.

110
Q

What is the nature of venous drainage for the gonads? (x2)

A

RIGHT SIDE: directly into IVC.
LEFT SIDE: left renal vein.

111
Q

What is the structure of the penis – excluding vasculature?

A
  • Corpus cavernosum are paired, and corpus spongiosum are the spongy structures of the penis shaft.
  • The corpus spongiosum contains the urethra and split into bulb, root, body and glans. NB: glans is part of the corpus spongiosum.
  • The frenulum of prepuce is the posterior fold of tissue that attaches skin to the head of the penis.
  • Penis has a deep and superficial fascia.
  • The crura (crus/legs) of the corpora cavernosa attach to the ischiopubic ramus – the crura are roots, and the area where the two crus join is called the body.
  • Navicular fossa is an area where catheters can get caught.
112
Q

What is the blood supply of the penis? (x4 + x1)

A
  • MAIN SUPPLY: INTERNAL PUDENDAL ARTERY from the internal iliac.
  • DEEP ARTERY supplies the corpora cavernosa.
  • DORSAL ARTERY supplies the skin and connective tissue.
  • ARTERY OF THE BULB supplies the bulb, corpus spongiosum, glans and urethra.
  • Branches of the cavernous spaces are usually called helicine arteries.
113
Q

How is the pelvis and perineum innervated? (x2 and x1)

A

Pelvic contents supplied by autonomic nerves only.

  • Sympathetic from lower thoracic and upper lumbar (T10 – L2) segments via hypogastric plexuses.
  • Parasympathetic from S2-S4 outflow = joins the inferior hypogastric plexus.

Perineum is supplied by the pudendal nerve which is SOMATIC by comparison, and originates from S2-S4.

114
Q

What is the sensory and motor function of the pudendal nerve? Trigger of motor function?

A

SENSORY: dorsal nerve of penis which is sensory to penile skin and glans. Also sensory to the anal canal and lower rectum.

MOTOR: contraction of perineal skeletal (voluntary) muscles (bulbospongiosus, ischiocavernous muscles and external urethral sphincter contraction) – causing ejaculation. SOMATIC REFLEX of contraction is triggered by entry of semen into urethra.

115
Q

What is the role of parasympathetic stimulation of penis? (x2)

A

(1) Causes helicine arteries to relax, allowing blood flow and erection – occurs when central PNS pathway is activated by psychic stimulation (occurs in males and females); (2) secretion in prostate and bulbourethral glands – from stimulation of parasympathetic ganglia.

116
Q

What is the purpose of sympathetic stimulation of penis? (x4)

A

(1) Contraction of smooth muscles of epididymis, vas deferens, seminal vesicles and prostate causing emission (discharge of contents of semen); (2) contraction of internal urethral sphincter in males to prevent reflux of semen; (3) bladder muscle contraction is prevented by sympathetic inhibitory action; (4) selected symapthetic nerves supplying pudendal arterioles are activated causing arteriolar constriction to restrict blood supply to cavernous spaces and limiting erection – detumescence.

117
Q

What are the stages of erection and ejaculation? And associated nervous stimulation?

A
  1. Erection – PNS.
  2. Secretion – PNS.
  3. Emission – SNS.
  4. Ejaculation – somatic.
  5. Detumescence – SNS (somatic).
118
Q

How is pain sensitised in the pelvic region?

A

Pelvic sensation is visceral and poorly localised – pain is referred to suprapubic region and perineum.

119
Q

What is the plexus associated with pudendal nerve S2-S4?

A

Lumbosacral plexus.

120
Q

What is the anatomical route of the pudendal nerve?

A

Passes briefly from pelvis to buttock, thus passing behind the fibrous posterior edge of Levator ani (the sacrospinous ligament). It passes forward below the Levator ani, first in the lateral wall of the ischioanal fossa (posterior perineum) then branching to anterior perineum, penis/clitoris and scrotum/vulva.

121
Q

What happens in dilation of the rectal veins?

A

Piles. Swellings containing enlarged blood vessels (haemorrhoids) found inside or around the bottom.

122
Q

What are the tissues surrounding the kidneys?

A

Surrounded by psoas major, quadratum lumborum and erector spinae muscles posteriorly (posterior abdominal walls). Anteriorly, there is the peritoneum and the renal fascia.

Surrounded entirely by pararenal fat.