Pharmacology Class Tuqa > Pen > Flashcards

Pen Flashcards

(71 cards)

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1
Q

Penicillin اي عالم اكتشفه

وعلى اي بكتريا

A

Alksander Fleming,staphylococcus

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2
Q

Penicillin can’t cross BBB

A

In normal condition but in meningitis can cross

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3
Q

Penicillin ionized or nonionized

A

Pencilin nonionzide outside the body

When enter the body become ionized

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4
Q

Which defrent betwen normal artery and cerebral artery

A

Normal artery contained poors can cross the fluid

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5
Q

Why Penicillin can cross the placenta but not teratogenic ¿

A

Because the fetal tissue absent transpeptidase enzyme pBP

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6
Q

Can retentions penicillin long time and not excretion

A

By giving probenecid inhibit excretion

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7
Q

Type of penicillin

A

1-benzylpeniciline (penicillinG)and related drug
2-antistaph penicillin
3-Extended spectrum penicillin
4-antipseudomonal penicillin

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8
Q

Which advantage and disadvantage of benzilypeniciline

A 
Advance 
1-streptococcus 
Stapheloccocase
Pneumonia 
ذولي تلاثتهم يكونونgram positive 
Sephalus 
Genase 
ذولي gram negative 
 هذا ينقاس بوحده الكونت لان يكون طبيعي

Disaadvantage
اول شي مينأخذoral لان يتأثر بلphمالت المعده
Intramuscular by 3-10time day
Spectrum of it narrowed

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9
Q

Procaine

A

Local ansethesia when driving to penicillin 24hour

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10
Q

Penzethine penciline

A

ننطق بلعضله كل ٣اسابيع حتى ميجيهم recurrent tonsillitis

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11
Q

Amoxicillin with clavulanic acid

A

=Co amoxiclave produce broaded spectrum

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12
Q

Amoxicillin concentration in

A

Bile effect liver disease and tophy

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13
Q

Ambicilin more active

A

Inshigula and influenza

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14
Q

Proimpiciline pivimpeicilin and talaimpicilin

A

More absorbed in blood and has no effect in the bectria flora

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15
Q

Which better absorbed impicilin or amoxicillin

A

Amoxicillin is better absorption and penetration than ampicillin

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16
Q

Aminoglycoside

A

Don’t cross BBB but can cross placenta

لهذا احنه مننطي للمرأه الحامل

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17
Q

Neomycin

A

Surgical in intestine oral high does ينطي لجراح علمود يعقم الامعاء

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18
Q

Benzyle penicillin

A

Treatment gram positive cocci streptococcus,staphylococcus,pnuemcocci,gram negative cocci gonococci ,meningococcus ,urinary tract infections

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19
Q

Vancomycin treatment +؛-bectria

A

Gram positive

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20
Q

Vancomycin

A

Don’t get orally

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21
Q

Red man syndrome

A

Caused by vancomycin because release histamine which cause rash skin

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22
Q

High dose of vancomycin can cause

A

Deafnease because injury in8nerve ,nephrotoxity,thrombonephlitic

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23
Q

Bactriacin

A

Inhibit building peptidoglycan block the active against positive bacteria

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24
Q

Bactricine in skin infection

A

Neomycins And polymixine

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25
Macrolide
Erythromycin,clerthromycin,azithromycin,roxithromycin
26
Macrolid
Act on 50s protein synthesis in small dose bactriostatic,in high dose bactriocidal
27
Erythromycin
Absorption effected by food and Hcl
28
Macrolid
Macrolid can penetrate organ tissue and placenta and small amounts penetrate csf
29
Arethromycin andazithromycin
Macrophages and nuatrophil and lung tissue
30
Macrolid execurtion and concentration
In liver bile
31
Clindomycine
Treatment of acne ,can penetrate bone and joint
32
Aminoglycoside
30s protein synthesis irreversible bond | better given as single large dose
33
Aminoglycoside
Gram negative aurobic
34
Aminoglycoside
Narrow spectrum
35
Aminoglycoside +penicillin
Synergism because penicillin facilated Aminoglycoside to enter
36
Aminoglycoside absorption
Not absorbed orally
37
Chloramphenicol
Gray baby syndrome
38
Function of GH
1-increase protein synthesis 2-increase free fatty acid in blood 3-decrease utilizing of glucose increase conservation of carbohydrates
39
Panhypopitutarsim
Decrease level all hormon of pituitary ,don’t developed sexual
40
Dwarfism
Def. In GH
41
Gintisim
Executive of GH
42
Deference between duration ,t1/2
T1/2 الزمن الي يبقى بي الدوا بالبلازما | Duration الزمن الي يبقى بي الدم بالانسجة
43
Floroqunalin
كلهم يعالجون uti ماعدا Moxifloxacin
44
Toboisonorize enzyme
HelpDNAto relax
45
Floroqunoline
Bacteria cidal
46
Fluroqunolin uses
``` 1-uti 2-RTI 3-osteomilites 4-meningitis 5-atypical صحصح التهاب السحايا راح نعالجه بصوره اساسيه عن طريق بينسلين بس المرضى الي عدهم حساسيه منه ومن كيفلوسبورين راح نجي ونستخدمه فلوروكينولون Atypical نسخدم بصوره اساسيه Macrolid بس المريض الي عنده حساسية منه نسخدمله ```
47
Cause of repture tendon Achilles
I ceprofloxoci
48
Floroqunolin,Macrolid
⬆️QT interval
49
Hypothyroidism,maxidema
T3;T4 decrease TSH ⬆️ | Cold ,fatigue ,depression
50
T4,T3
T4 7day | T3 1day
51
Sulfoamide
كلهم نفس الشي ماعدا انو اكو اختلاف بلفارماكاينتك
52
Kerniktrase
Sulfonamide | In the baby below 2year blirubine pass bbb
53
Sulfonamid
Teratogenic
54
Any drug inhibit folic acid
Megaloplastic anemia,neural tube effect
55
Metronidazole don’t use to treatment uti بلرغم | انو ٦٠٪؜من عنده ينزل بدون تغير
Because this drug specialised anaerobic Bactria and UTI erobic Bactria
56
Short acting penicillin
Benzyle penicillin
57
Methicillin, cloxacillin, dicloxacillin, flucloxacillin, and nafcillin]
They are effective against p-lactamase producingStaphylococci.
58
Penicillin high dose
Neurotoxicity,seizure,renal failure
59
Naficilin
Neutropenia, thrombocytopenia,
60
Methecilin
Interstitial nephritis,
61
Coamxicalve,
Cholistatic jaundice
62
Some organ receive single supply of ANS
Suprarenal gland ,blood supply,sweat gland
63
Systole ,dystole
S CO | Dystole pr
64
Personal متنرفز والعصبي
نعطي الفا 2
65
Beta1
Found in kidney and hearts
66
B3
Adybocyt
67
Beta2
الطيبه مالها اثار جانبيه 🤍📝
68
Penzodiyzabine
اي شخص تسمم بدوا cns stimulation
69
Migraine
صداع نصفي
70
Corenary artery
The only artery filled in dystole
71
Superior mesntric ,splanchnic
Portal veins

Pharmacology Class Tuqa (3 decks)

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