Perfusion Flashcards

1
Q

perfusion

A

the process of nutrient delivery of arterial blood to a capillary bed
(supplying an organ or tissue with oxygen and nutrients)

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2
Q

noninvasive assessment of perfusion

A

LOC
skin
urine output
color, BP, HR
capillary refill time

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3
Q

perfusion scanning methods

A

CT perfusion
MRI perfusion
nuclear medicine perfusion

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4
Q

cardiac output

A

the amount of volume/blood ejected/pumped from the heart in one minute
CO=HR*SV

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5
Q

normal CO

A

4-8L/min

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6
Q

normal cardiac index

A

2.4-4 L/min

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7
Q

stroke volume

A

volume of blood pumped with each heartbeat

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8
Q

normal SV

A

60-70mL with each ventricular contraction

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9
Q

impact of HR on CO

A

severe increase in HR decreases SV due to decreased filling time, and therefore decreased CO

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10
Q

four determinants of CO

A

heart rate
contractility
preload
afterload

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11
Q

preload

A

amount of blood in ventricle at end of diastole
the degree of stretch in myocardial fibers at the end of diastole
the end diastolic ventricular volume
a function of volume and ventricular compliance

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12
Q

factors affecting preload

A

volume: venous return, total blood volume, atrial kick
compliance: stiffness and thickness of ventricular wall

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13
Q

manifestations of decreased preload

A

tachycardia
decreased urine output
increased specific gravity
dry mucous membranes
tented skin
sunken eyes
orthostatic hypotension

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14
Q

increased preload

A

JVD
pedal edema
S3, S4
crackles
dyspnea
pink frothy sputum
ascities, hepatic engorgement

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15
Q

medications affecting preload

A

fluids
diuretics
venodilators: nitrates, morphine, ACE inhibitors

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16
Q

frank starling law of heart

A

increasing venous return, increases filling pressure of the ventricle will lead to increased force of contraction and stroke volume

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17
Q

afterload

A

ventricular pressure at the end of systole, the resistance against which the heart pumps blood

18
Q

factors affecting afterload

A

aortic impedance
blood viscosity
blood volume
vascular tone

19
Q

systemic vascular resistance

A

resistance to ejection from left side of heart
normal 800-1200

20
Q

pulmonary vascular resistance

A

resistance to ejection from right side of heart
normal 50-250

21
Q

increased afterload

A

pale, cool, clammy skin
HTN
non-healing wounds
thick, brittle nails
slow cap refill
decreased urine output

22
Q

decreased afterload

A

warm, flushed skin
increased CO
decreased BP

23
Q

contractility

A

the ability of a muscle to shorten when stimulated
the force of myocardial contraction
independent of preload & afterload
SNS and PNS innervation
measured as EF

24
Q

decreased contracility

A

hypotension
fatigue
SOB
dizziness
low urine output

25
increased contractility
increased blood pressure
26
indications for hemodynamic monitoring
alterations in cardiac output alterations in fluid volume alterations in tissue perfusion
27
central venous pressure
volume/pressure on the right side of the heart reflects filling pressures in the right ventricle guides overall fluid balance
28
noninvasive hemodynamic technologies
impedance cardiography doppler ultrasound
29
minimally hemodynamic technologies
CVP arterial access line MAP
30
arterial line indications
monitoring blood pressure frequent ABGs
31
pulmonary artery catheter advantages
real-time data measure a variety of hemodynamic parameters able to rapidly assess pts response to interventions
32
PA catheters disadvantages
infection insertion complications air emboli, exsanguination balloon rupture pulmonary artery rupture
33
pulmonary artery wedge pressure
4-12mmHg reflects left side preload
34
pulmonary artery pressure
20-30/10s mmHg blood pressure
35
central venous pressure
2-6mmHg reflects right sided preload
36
pulmonary vascular resistance
50-250 dynes/sec/cm-5 reflects right sided afterload
37
systemic vascular resistance
800-1200 dynes/sec/cm-5
38
pulmonic valve stenosis/calcification
insidious process that happens over time increased afterload on right ventricle
39
pulmonary hypertension
increased afterload on right ventricle, which impacts right ventricular emptying
40
interventions for elevated PA pressures
find cause/root of problem reduction in preload (circulating volume) decrease venous return to the right side increase/improve contractility meds: vasodilators, diuretics, Na and fluid restriction, valve replacement/repair