Peripartum/Pregnancy Flashcards

1
Q

The 2 objectives of Healthy People 2020 for pregnant women include: 1) Reduce pre-term births and low birth weight and 2)

A

Abstinence from tobacco/drugs/alcohol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Teratogen risk is highest in weeks __ to __ of pregnancy

A

3-8 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

____ psychotropic meds cross the placenta and are excreted in breast milk

A

ALL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

**The foundation of decision making process for use of meds during pregnancy is:

A

weighing the risk of untreated mental illness vs. risk of medication effects on baby

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

**What does the latest research recommend in regard to med dosages vs. adjunct meds during pregnancy?

A

Maximize dosage of drugs BEFORE adding adjunct med

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dose reductions in psychotropic meds due to concerns about harming baby can lead to:

A

subtherapeutic treatment in mom which increases risks for both mother and baby

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The introduction of this new system in 2015 requires all medications to include reproductive and lactation information in their package insert, including any effects a medication could have on males reproductive health.

A

Pregnancy and Lactation Labeling Rule (by FDA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

This depression screening tool is specific to pregnant women

A

Edinburgh Pregnancy Depression Scale (EPDS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

This is the 1st-line treatment for perinatal depression

A

SSRIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

These 4 SSRIs are considered to be the safest to use during pregnancy:

A

sertraline
fluoxetine
escitalopram
citalopram

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

This class of drugs have been associated with low birth weight, pre-term birth, postpartum hemorrhage and PERSISTENT PULMONARY HYPERTENSION (PPH) in the newborn

A

SSRIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

This antidepressant is associated with congenital heart defects in the newborn (VSD, ASD)

A

paroxetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

This antidepressant may be helpful for both depression and HYPEREMESIS GRAVIDARUM (severe N/V associated with pregnancy)

A

mirtazapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

For rapid symptom relief (suicidality), psychotic agitation, minimal response to meds, this may be indicated according to APA and ACOG

A

ECT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

This treatment for perinatal depression increases risk for pre-term labor, placental abruption (placenta separating from uterus), and SPONTANEOUS ABORTION

A

ECT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Non-pharm TXs such as CBT, IPT and ___ ___ ____ may be effective for perinatal depression

A

Bright Light Therapy (BLT)

17
Q

Fetal risks for this psychiatric disorder include pre-term birth, low birth weight, PLACENTA PREVIA (placenta partially or completely covers mother’s cervix), PRE-ECLAMPSIA (severe HTN leading to potential organ damage)

A

Perinatal Bipolar Disorder

18
Q

This rare congenital heart defect is associated with perinatal use of lithium

A

Ebstein’s anomaly

19
Q

When using atypical antipsychotics during pregnancy, should stick to:

A

Older, more widely-researched agents

20
Q

The most serious risk associated with bipolar disorder for mothers during pregnancy is:

A

suicide

21
Q

What are some administration and monitoring considerations for lithium in pregnant women? (2 answers)

A

BID instead of QD dosing

Monitor renal fx (creatinine)

22
Q

Some institutes recommend avoiding the use of this drug for any women of childbearing age unless they have had a tubal ligation or hysterectomy

A

Depakote

23
Q

The 1st-line tx of mild-moderate anxiety in pregnancy is

A

CBT

24
Q

The 2nd-line tx for anxiety disorders in pregnancy is:

A

CBT + SSRI

25
Q

What did a meta-analysis by NICE show in regard to risk of fetal malformations related to benzodiazepine use?

A

No increase in risk for fetal malformations.

26
Q

Benzo use during pregnancy can result in these 2 issues in the baby

A

Withdrawal syndrome

Floppy baby

27
Q

Perinatal _____ can increase risk for hyperemesis gravidarum (HG) and immunosuppression

A

Anxiety

28
Q

Taking an antihistamine on same day as a _____ can increase the risk of _____

A

benzo

increased risk of stillbirth

29
Q

There is very little research on this anxiolytic so it is best avoided during pregnancy

A

buspirone

30
Q

These 2 antidepressants and this 1 hypnotic are reasonably safe options to help with sleep issues during pregnancy

A

trazodone and mirtazapine

zolpidem (Ambien)

31
Q

Gestational diabetes, preeclampsia, placental abruption, preterm birth, small for gestational age (SGA), LGA (especially with ATYPICALS), cardiac abnormalities (RISPERIDONE), and neglect are all risks for women with this condition

A

Perinatal Schizophrenia

32
Q

Both FGA and atypicals may increase risk for this complication in the newborn

A

over-sedation (sometimes requiring mechanical ventilation)

33
Q

This ADHD med is associated with cardiac malformations when taken during the first trimester of pregnancy

A

methylphenidate

34
Q

This is the preferred stimulant to use during breastfeeding due to lower levels of transmission in breast milk

A

methylphenidate (as compared to amphetamine)

35
Q

What is the research on safety in regard to the use of guanfacine, clonidine and atomoxetine during pregnancy?

A

Limited data (should be avoided)

36
Q

This drug is considered relatively safe during pregnancy and can be used off-label for ADHD

A

bupropion

37
Q

These 2 antipsychotics have lower transmission in breast milk:

A

olanzapine

quetiapine

38
Q

This benzo has a short half life and low transmission through breast milk

A

lorazepam

39
Q

This antipsychotic can DECREASE prolactin levels and so can decrease breast milk production. Also, this other class of drugs can decrease milk production

A

aripiprazole

anticholinergics/antihistamines