Peripheral Nerves and ANS Flashcards

(48 cards)

1
Q

from skin, muscle, and joints

A

somatic afferents

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2
Q

from organs; can travel through the spinal cords or vagus from medulla

A

visceral afferents

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3
Q

Types of afferent receptors (3)

A
  1. ) nociceptors
  2. ) mechanoreceptors
  3. ) proprioceptors
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4
Q

detect pressure or stretch

A

mechanoreceptors

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5
Q

respond to chemicals

A

nociceptors

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6
Q

detect changes in muscle or tendon length/tension ; help to sense positioning

A

proprioreceptors

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7
Q

motor neuron and all the skeletal muscle fibers it innervates

A

motor unit

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8
Q

antagonist/block neuronal Na+ channels

A

tetrodotoxin

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9
Q

antagonist/blocks Ca2+ channel

A

Conotoxin

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10
Q

antagonist for ACH release

A

botulinum toxin

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11
Q

antagonist for acetylcholinesterase

A

physostigmine

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12
Q

agonist for AChR channel (2)

A

1.) Ach 2.) nicotine

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13
Q

antagonist for AChR channel

A

tubocurarine, curare

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14
Q

Three things that occur during inspiration

A
  1. ) HR increases
  2. ) Decrease in parasympathetic output from ANS
  3. ) Increases in cardiac pacemaker
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15
Q

3 things during expiration

A
  1. ) HR decreases
  2. ) increase in parasympathetic output from ANS
  3. ) slows cardiac pacemaker
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16
Q

True/False: alpha 1 adrenergic receptors has more affinity to NE

A

TRUE

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17
Q

True/False: Alpha 2 has more affinity for epi

A

TRUE

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18
Q

Beta 1 has more affinity for ___.

A

Epi

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19
Q

increases heart rate and cardiac contractility

A

beta 1

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20
Q

which receptor has a much greater response to epi?

21
Q

Bronchodilation, some vasodilation from this receptor

22
Q

All preganglionic neurons release which NT

23
Q

postganglionic sympathetic neurons release

24
Q

Overactivation of muscarinic receptors (mnemonic)

A

DUMBELSS (more parasympathetic activation)

Diarrhea, urination, miosis (pupil constriction), bradycardia, emesis, lacrimation, salivation, sweating

25
more sympathetic tone/ innervation
blood vessels
26
more parasympathetic tone/innervation
gut
27
sympathetic innervation
sweat glands
28
hexamethonium blocks N2 receptors what does this do to blood pressure?
drops blood pressure; vessels are under sympathetic innervation
29
Examples of autonomic reflex in gut
vago vagal reflex in response to gastric distension
30
Describe how baroreceptor reflex works
1. ) when bp is high, reflex reduces HR and BP | 2. ) when bp is low, reflex raises HR and BP
31
parasympathetic reflex of the ANS to lower heart rate during heart damage
coronary chemoreflex
32
stimulation of cardiac vagal afferents by inflammatory substances lead to ____
stimulation of AP's and drop in HR and drop in BP
33
What are some way to therapeutically manipulate the ANS?
1. ) receptor agonists/antagonists 2. ) block of breakdown of NT 3. ) packaging of NT
34
agonists for Epi/NE system receptors
1. ) epinephrine 2. ) norepinephrine 3. ) phenylephrine 4. ) albuterol
35
beta 2 receptor agonist
albuterol
36
alpha 1 receptor agonist
phenylephrine
37
antagonist of beta receptor
propranolol
38
agonist of Ach receptor system
pilocarpine
39
Ach muscarinic receptor agonist
pilocarpine
40
antagonist of Ach muscarinic
atropine and glycopyrrolate
41
What breaks down dopamine and NE in the nerve terminal?
monoamine oxidase | catecholomethyl transferase
42
What would treatment with reserpine do to BP ?
lowers BP
43
part of brain involved in memory
hippocampus
44
part of brain involved in emotion or fear response
amygdala
45
sweat glands innervated by
cholinergic postganglionic sympathetic
46
adrenal medulla receives synaptic input from ___
preganglionic sympathetic
47
which receptor is found between synapses between preganglionic and postganglionic neurons of the sympathetic system?
nicotinic
48
nasal, lacrimal, and salivary glands are stimulated by what?
Ach