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Flashcards in Pestana Organ Transplantation Deck (10)
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1

absolute contraindication to organ donation

HIV+ status

2

3 ways transplant rejection can happen

hyperacute
acute
chronic

3

When does hyperacute rejection occur?

within MINUTES of reestablishing blood supply to the transplanted organ - caused by preformed antibodies

4

How do you prevent hyperacute rejection?

ABO matching and lymphocytotoxic cross-matching

5

When does acute rejection occur?

>5 DAYS but within the first 3 MONTHS

6

What should you do if LFTs begin to rise in a patient with transplanted liver?

R/O biliary obstruction by US and vascular thrombosis with Doppler

7

Management of a patient with transplanted heart?

routine ventricular biopsies since signs of functional deterioration usually occur too late to allow effective therapy

8

Treatment of acute rejection?

Steroid boluses (1st line)
Lympocyte agents (OKT3)
Antithymocyte serum

9

When does chronic rejection occur?

YEARS, with insidious loss of organ function

10

Treatment of chronic rejection?

no treatment