PF- NEWBORN SCREENING Flashcards
(64 cards)
What is the RA for newborn screening
r.a 9288
RA 9288 is also known as
known as Newborn Screening Act of 2004
what is newborn screening
Process of collecting a few drops of blood from the newborn onto an appropriate collection
card and performing biochemical testing to determine of the newborn has a heritable
condition
promulgating a comprehensive policy and a national system for ensuring Newborn Screening, known as Newborn Screening Act of 2004
R.A 9288
when is newborn screening performed
after 24hrs of life not later than 3 days from complete delivery of the newborn
what are the six disorders newborn screening is used to detect
- Congenital Hypothyroidism
- Congenital Adrenal Hyperplasia (CAH)
- Phenylketonuria
- Glucose-6-Phosphate Dehydrogenase Deficiency
(G6PD) - Galactosemia (GAL)
- Maple Syrup Urine Disease (MSUD)
previously known deficiency of
thyroid hormone in newborns.
Congenital hypothyroidism,
It causes impaired neurological function, stunted growth, and physical deformities.
congenital hypothyroidism
what are the two main possible causes of congenital hypothyroidism
- problem with the baby’s thyroid gland
- lack of iodine in the mother’s body during pregnancy
specific causes for congenital hypothyroidism
-missing, poor form, abnormally small thyroid gland
-genetic defect affecting the production of thyroid hormone production
- little iodine in mother’s diet during pregnancy
-radioactive/antithyroid treatment for thyroid cancer during pregnancy
- medicine that disrupt thyroid hormone production- antithyroid, sulfonamides, lithium
a pregnant mother is diagnosed with thyroid cancer and is prescribed antithyroid treatment, what possible condition can the newborn experience?
a. congenital adrenal hyperplasia
b. congenital hypothyroidism
c. phenylketonuria
b. congenital hypothyroidism
a child with congenital hypothyroidism can experience mental retardation if not treated, how many IQ points do they decrease and for how long
A child’s IQ can drop several points 1 every
few months that treatment is delayed.
what are the complications that come with congenital hypothyroidism?
-abnormal walk
- muscle spasticity
- inability to speak
- autistic behavior
- vision and hearing problems
-problem with memory and attention
in a specific developing country, pregnant women have been seen to be commonly deficient in iodine. What can this be an indication for the newborn?
congenital hypothyroidism
who recommends the RDA
INSTITUTE OF MEDICINE
WHAT DOES RDA STAND FOR
RECOMMENDED DIETARY ALLOWANCE,
According to the institute of medicine, what is the RDA for iodine?
150 micrograms per day-
1 tsp of salt= 400 mcg
what are the signs and symptoms of congenital hypothyroidism
- lack of weight gain
- stunted growth
- abnormal bone growth
- thickened facial features
- hoarse voice
- floppy, low muscle tone
- jaundice, excessive sleep, poor feeding, very little crying
this is described as walnut-sized organ above the kidney
adrenal glands
refers to a group of genetic disorders that affect the adrenal glands, a pair of walnut-sized organs above the kidneys.
congenital adrenal hyperplasia (CAH)
what are the three important hormones the adrenal gland produces?
cortisol
mineralocorticoids
androgens
this hormone g: Regulating your body’s stress response. Helping control your body’s use of fats, proteins and carbohydrates, or your metabolism
cortisol
these are a class of steroid hormones that regulate salt and water balances.
Mineralocorticoids
these are crucial for male sexual and reproductive function. They are also responsible for the development of secondary sexual characteristics in men, including facial and body hair growth and voice change. Androgens also affect bone and muscle development and metabolism.
androgen
