Pharm

Question 1

HER2/neu+ breast cancer

Answer 1

Trastuzumab

Question 2

Buerger disease (vasculitis)

Answer 2

Smoking cessation

Question 3

Ia antiarrhythmic

Answer 3

quinidine, procainamide, disopyramide

Question 4

Tourette

Answer 4

Antipsychotics, tetrabenazine

Question 5

Ribavirin MOA

Answer 5

inhibit duplication of viral genetic material

Question 6

Breast cancer in postmenopausal women

Answer 6

Anastrozole

Question 7

PDA

Answer 7

Close with indomethacin. Keep open with PGE

Question 8

Treatment for Torsades

Answer 8

Magnesium sulfate

Question 9

Chlamydia

Answer 9

Doxy+ceftriaxone

Erythromycin eye drops

Question 10

Schizophrenia

Answer 10

Atypical antipsych for pos and neg sym. Typical just for pos

Question 11

Erectile dysfunc

Answer 11

Sildenafil, tadalafil, vardenafil

Question 12

Clostridium botulinum and tetani

Answer 12

Antitoxin

Question 13

SIADH

Answer 13

Fluid restriction, IV hypertonic saline, conivaptan/tolvaptan, demeclocycline

Question 14

Osteoporosis

Answer 14

Calcium, vit D as prophylaxis

Bisphosphonates, PTH analogs, SERMs, calcitonin, deosumab

Question 15

Meds that incr risk for osteoporosis

Answer 15

antiepileptics, aromatase inhibs, GnRH agonists, PPIs, glucocorticoids

Question 16

Ulcerative colitis

Answer 16

5-ASA preps like mesalamine, 6-mercaptopurine, infliximab, colectomy

Question 17

Prolactinoma

Answer 17

Cabergoline/bromocriptine (dopamine agonists)

Question 18

Pheochromocytoma

Answer 18

Alpha-antags like phenoxybenzamine

Question 19

Temporal arteritis

Answer 19

High dose steroids

Question 20

Pulm arterial hypertension

Answer 20

Sildenafil, bosentan, epoprostenol

Question 21

Cyclophosphamide-induced hem cystitis

Answer 21

Mesna

Question 22

Crohn

Answer 22

Corticosteroids, infliximab, azathriprine

Question 23

PTSD

Answer 23

SSRI, venlafaxine

Question 24

Acute gout

Answer 24

NSAIDs, colchicine, glucocorticoids

Question 25

GAD

Answer 25

SSRI, SNRI | Buspirone is second line

Question 26

Drugs for chemo-induced nausea

Answer 26

Dopamine and serotonin recep antags ie prochlorperazine, metoclopramide, ondansetron

Question 27

Sickle cell

Answer 27

Hydroxyurea (incr HbS)

Question 28

Candida

Answer 28

topical azoles, nystatin, fluconazole, caspofungin, amph B

Question 29

Tonic-clonic seizures

Answer 29

Levetiracetam, phenytoin, valproate, carbamazepine

Question 30

K+ sparing diuretics

Answer 30

Spironolactone, amiloride, triamterene

Question 31

Warfarin reversal

Answer 31

Fresh frozen plasma (acute), vit k (non-acute)

Question 32

Drugs for motion sickness

Answer 32

M1 and H1 antags

Question 33

Neural tube defect prevention

Answer 33

Prenatal folic acid

Question 34

Prostate adenocarcinoma/uterine fibroids

Answer 34

Leuprolide, continuous GnRH | Flutamide just for prostate

Question 35

Social anxiety disorder

Answer 35

SSRI, velafaxine | Performance only: propanolol, benzo

Question 36

Bipolar

Answer 36

Lithium, valproic acid, carbamazepine, lamotrigine, atypical antipsychotics

Question 37

Anorexia

Answer 37

Nutrition, psychotherapy, mirtazapine

Question 38

Acute promyelocytic leukemia

Answer 38

All-trans retinoic acid

Question 39

Migraine

Answer 39

Abortive: triptans, NSAID Prophylaxis: propanolol, topiramate, CCBs, amitriptyline

Question 40

Medical abortion

Answer 40

Mifepristone

Question 41

Schizophrenia

Answer 41

Atypical antipsychotics

Question 42

Osteomalacia/rickets

Answer 42

Vit D

Question 43

Streptococcus bovis

Answer 43

Penicillin; Eval for colon cancer

Question 44

Hyperaldosteronism

Answer 44

Spironolactone

Question 45

Toxo gondii

Answer 45

Sulfadiazine and pyrimethamine

Question 46

--cept

Answer 46

receptor molecule

Question 47

Chronic gout

Answer 47

Allopurinol, febuxostat (XO inhibs), pegloticase, probenecid

Question 48

Hypertriglyceridemia

Answer 48

Fibrate

Question 49

BPH

Answer 49

alpha-1-antags (zosin), 5alpha reductase inhibs, PDE-5 inhibs

Question 50

Pseudomonas

Answer 50

Antipseud penicillins, aminoglycosides, carbapenems

Question 51

Ic antiarrhythmics

Answer 51

propafenone, flecainide

Question 52

C diff

Answer 52

Metronidazole or oral vanc

Question 53

Amantadine MOA

Answer 53

Impair uncoating of influenza A when it's endocytosed

Question 54

Panic disorder

Answer 54

SSRI, venlafaxine, benzo

Question 55

CMV

Answer 55

Ganciclovir, foscarnet, cidofovir

Question 56

Anticoag during pregnancy

Answer 56

Heparin

Question 57

Malaria

Answer 57

chloroquine, mefloquine, atovaquone/proguanil (blood schizont), primaquine (liver hypnozoite)

Question 58

Drug-induced long QT

Answer 58

antiArrhythmics (Ia, III), antiBiotics (macrolide), antiCychotics (haloperidol), antiDepressants (TCAs), antiEmetics (ondansetron)

Question 59

Cryptococcus neoformans

Answer 59

Fluconazole

Question 60

MS

Answer 60

Disease modifying: beta-interferon, natalizumab | IV steroids for acute flares

Question 61

Drugs that improve long term survival in HF

Answer 61

beta blockers, ACE-Is, ARBs, aldosterone antags

Question 62

heparin reversal

Answer 62

Protamine sulfate

Question 63

Triptan MOA

Answer 63

Serotonin receptor agonist

Question 64

Infertility

Answer 64

Leuprolide, GnRH, clomiphene

Question 65

CML

Answer 65

imatinib

Question 66

class III antiarrhythmics

Answer 66

amiodarone, ibutilide, dofetilide, sotalol

Question 67

ethylene glycol/methanol intox

Answer 67

Fomepizole (alc dehydrogenase inhib)

Question 68

DKA

Answer 68

Fluids, insulin, K+

Question 69

ER+ breast cancer

Answer 69

tamoxifen

Question 70

Myasthenia gravis

Answer 70

Acetylcholinesterase inhib (pyridostigmine, physiostigmine etc) & selective muscarinic antagonist (glycopyrrolate, hyoycyamine, propantheline) to reduce SEs

Question 71

H pylori infection

Answer 71

PPI, antibiotic (tetracycline, metronidazole), bismuth subsalicylate

Question 72

OCD

Answer 72

SSRI, venlafaxine, clomipramine

Question 73

Alcohol withdrawal

Answer 73

Long-acting benzos (chlordiazepoxide, lorazepam, diaxepam)

Question 74

Granulomatosis with polyangitis (Wegener)

Answer 74

Cyclophosphamide, corticosteroids

Question 75

--nib

Answer 75

kinase inhibitor

Question 76

UTI prophylaxis

Answer 76

TMP-SMX

Question 77

Ib antiarrhythmics

Answer 77

lidocaine, mexilientine, (phenytoin)

Question 78

Kawasaki

Answer 78

IVIG, high dose aspirin

Question 79

Trigeminal neuralgia

Answer 79

Carbamazepine

Question 80

Malignant hyperthermia

Answer 80

Dantrolene

Question 81

Chronic hep B or C

Answer 81

IFN-gamma | Ribavirin, semiprevir, sofosbuvir (for C)

Question 82

Bulimia

Answer 82

SSRI

Question 83

Arrhythmia in damaged cardiac tissue

Answer 83

IB antiarrhythmics: lidocaine, mexiletine

Question 84

Diabetes insipidus

Answer 84

Desmopressin, hydrochlorithiazide, indomethacin, amiloride