Pharm EENT FC (PN) Flashcards
(14 cards)
This antihistamine may cause tardive dyskinesia with long term use and should not be combined with antidepressant medications.
Hydroxyzine
his medication is contraindicated in closed-angle glaucoma because it dilates the eyes- as part of its anti-cholinergic side effects. It is also contraindicated in BPH and with MAOIs.
Diphenhydramine
A first generation H1-receptor antagonist used for motion sickness, insomnia, and seasonal allergies (not Meclizine)
Diphenhydramine
Indications of Hydroxyzine
Allergic Rhinitis & Allergic Skin Disorders
Motion sickness
Mild Anxiety
MOA of Hydroxyzine
H1 receptor antagonist
Anti-serotonergic
SE of Hydroxyzine
Sedation
Dizziness & Hypotension
Tardive Dyskinesia with long-term use
CI of Hydroxyzine
Pregnancy
In combination with depressant drugs
Indications of Pseudoephedrine/Oxymetazoline
Nasal congestion & Asthma
Weight loss (off-label)
Urinary Incontinence
MOA of Pseudoephedrine/Oxymetazoline
Alpha adrenergic agonist (sympathomimetic) that is weaker than ephedrine
SE of Pseudoephedrine/Oxymetazoline
HTN, tachycardia
CNS overstimulation (insomnia, tremors)
Rebound rhinorrhea
CI of Pseudoephedrine/Oxymetazoline
HTN Hyperthyroidism Diabetes Urinary Retention Insomnia Glaucoma
Interactions of Pseudoephedrine/Oxymetazoline
Other sympathomimetics = MAOIs, caffeine
May increase the toxicity of theophylline
This medication may cause drowsiness, it may shorten a menstrual cycle, and cause anti-cholinergic effects: dry eyes, dry mouth, constipation, blurry vision, mydriasis
Diphenhydramine
Alpha-agonistic nonprescription nasal decongestant that may cause hypertension and tachycardia. It may also cause urinary retention
Pseudoephedrine
