Pharm EENT FC (PN) Flashcards
This antihistamine may cause tardive dyskinesia with long term use and should not be combined with antidepressant medications.
Hydroxyzine
his medication is contraindicated in closed-angle glaucoma because it dilates the eyes- as part of its anti-cholinergic side effects. It is also contraindicated in BPH and with MAOIs.
Diphenhydramine
A first generation H1-receptor antagonist used for motion sickness, insomnia, and seasonal allergies (not Meclizine)
Diphenhydramine
Indications of Hydroxyzine
Allergic Rhinitis & Allergic Skin Disorders
Motion sickness
Mild Anxiety
MOA of Hydroxyzine
H1 receptor antagonist
Anti-serotonergic
SE of Hydroxyzine
Sedation
Dizziness & Hypotension
Tardive Dyskinesia with long-term use
CI of Hydroxyzine
Pregnancy
In combination with depressant drugs
Indications of Pseudoephedrine/Oxymetazoline
Nasal congestion & Asthma
Weight loss (off-label)
Urinary Incontinence
MOA of Pseudoephedrine/Oxymetazoline
Alpha adrenergic agonist (sympathomimetic) that is weaker than ephedrine
SE of Pseudoephedrine/Oxymetazoline
HTN, tachycardia
CNS overstimulation (insomnia, tremors)
Rebound rhinorrhea
CI of Pseudoephedrine/Oxymetazoline
HTN Hyperthyroidism Diabetes Urinary Retention Insomnia Glaucoma
Interactions of Pseudoephedrine/Oxymetazoline
Other sympathomimetics = MAOIs, caffeine
May increase the toxicity of theophylline
This medication may cause drowsiness, it may shorten a menstrual cycle, and cause anti-cholinergic effects: dry eyes, dry mouth, constipation, blurry vision, mydriasis
Diphenhydramine
Alpha-agonistic nonprescription nasal decongestant that may cause hypertension and tachycardia. It may also cause urinary retention
Pseudoephedrine
