Pharm: HTN, CAD

Question 1

3 main SE of ACEi

Answer 1

hyperK, dry cough, angioedema

Question 2

avoid what abx for pt on ACE/ARB

Answer 2

bactrim

Question 3

pt on ACEi still doesn’t have control of BP. increase dose or add another med?

Answer 3

add another class of HTN med

Question 4

ACEi monitoring

Answer 4

BMP

Question 5

only ARB to not cause hyperuricemia

Answer 5

losartan

Question 6

preferred diuretic for HTN pts w/o complications

Answer 6

chlorthalidone

Question 7

pt who is allergic to sulfa cannot take which 2 classes of HTN meds

Answer 7

thiazides, loops

Question 8

thiazides, loops can increase blood levels of — (2)

Answer 8

uric acid, glucose

Question 9

thiazides, loops – do they cause hyperK or hypoK?

Answer 9

hypo

Question 10

when does hypoK develop from loops/thiazides?

Answer 10

w/in first 2 wks, then stabilises

Question 11

should CCBs be used in HF?

Answer 11

no

Question 12

which CCBs are cardio selective

Answer 12

Non-dihyrophyridines aka Cardioselective CCBs (diltiazem, verapamil)

Question 13

3 main SEs of CCBs

Answer 13

HA, LE edema, constipation

Question 14

CI to rx BB + what type of CCB

Answer 14

Non-dihyrophyridines aka Cardioselective CCBs (diltiazem, verapamil)

Question 15

when is it NOT ok to give BB in HF?

Answer 15

NYHA class 4 (HF symptoms at rest) or acute decompensated HF

Question 16

labetalol class

Answer 16

mixed beta / alpha 1 antagonists

Question 17

class: Isosorbide dinitrate/hydralazine (BiDil®)
Hydralazine (Apresoline®)

Answer 17

direct vasodilators

Question 18

most effective class at deccreasing LDLs

Answer 18

statins

Question 19

most effective class at increasing HDLs

Answer 19

nicotinic acid

Question 20

most effective class at deccreasing trigs

Answer 20

Fibric Acid Derivatives / Fibrates

Question 21

high intensity statins (2) and doses (4)

Answer 21

Atorvastatin (Lipitor) (40, 80mg = high intensity)
Rosuvastatin (Crestor) ( 20-40mg = high intensity)

Question 22

main statin SE and the biggest culprit med

Answer 22

Myopathy (most common; simvastatin main culprit; hypothyroidism predisposes

Question 23

class: “Colestipol (Colestid®)
Colesevelam (WelChol®)
Cholestyramine (Questran®)”

Answer 23

bile acid sequestrants

Question 24

bile acid sequestrants can increase ____ levels

Answer 24

trigs

Question 25

pt education for new colestid rx and pt is already taking statin

Answer 25

take 1 hr before or 2 hr after statin

Question 26

CI: gemfibrozil + ______

Answer 26

statins

Question 27

which med decreases dietary absoprtion of cholesterol

Answer 27

Ezetimibe (Zetia)

Question 28

pt ed for omega 3 pills

Answer 28

take w/ food

Question 29

samter’s triad of people who may have increased risk of severe salicylate sensitivity

Answer 29

nasal polyps, chronic rhinitis, asthma

Question 30

is plavix indicated for arterial or venous thromboembolism?

Answer 30

arterial. NOT venous

Question 31

besides STEMI at a non PCI facility and ischemic stroke, when is TPa indicated?

Answer 31

large PE or DVT

Question 32

preferred anticoagulant in pregnancy

Answer 32

LMWH

Question 33

heparin reversal agent

Answer 33

protamine

Question 34

which anticoag can be used in pts w/ mechanical heart valve?

Answer 34

warfarin

Question 35

must bridge warfarin w/ lovenox for first ____ days

Answer 35

5

Question 36

reversal agent for eliquis and xarelto

Answer 36

Andexxa

Question 37

Pt ed for xarelto

Answer 37

must take w/ food and at same time every day

Question 38

when starting HF pt on BB, warn them ____

Answer 38

sx might get worse at the beginning

Question 39

stop BB in very sick pts w/ acute decompensated HF X 4wks and use these.

Answer 39

“Beta agonists: Dobutamine
Dopamine”