Pharm Quiz 2 - instructor review Flashcards Preview

Adv Patho & Pharm 2018 > Pharm Quiz 2 - instructor review > Flashcards

Flashcards in Pharm Quiz 2 - instructor review Deck (22):
1

alpha 2 agonist - used to treat

HTN (clonidine) (alpha 2 causes some vasodilation)
PTSD

2

parkinson's cause and treatment

loss of dopamine-producing neurons in brain causing unopposed ACh activity

treat with anticholinergic med and dopa supplementation

3

ALZ treatment

AChEI to increase ACh activity, which enhances memory

4

treatment for spastic bladder

anticholinergic
alpha 1 agonist - relaxes smooth muscle and constricts sphincter

5

anticonvulsants work by

slowing Na+ movement through channels

6

serotonin syndrome s/s

HTN, hyperreflexia, tremor, tachycardia -->> seizures, hyperpyrexia

7

SSRI withdrawal

flu-like symptoms

8

common AEs antidepressants

weight gain, loss of libido

9

with a first gen antipsychotic watch for (4)

1. Movement issues: akathesia, tardive dyskinesia, NMS
2. Cardiac: prolonged QT,
3. Liver function
4. Metabolic syndrome

10

possible AEs of stimulants for ADHD

anorexia --> weight loss, change in sleep pattern, EKG changes/arrhythmias

11

if you get a high TSH in a screen

confirm with free T4-should be low, this will confirm hypothyroidism

12

advantages of metformin for DMII starting treatment

cheap, low risk of HoGly, lowers lipids, weight neutral

13

when would you choose an SU for DMII?

renal disease-can't use metformin or DPP4
poor control with metformin alone
cheap
lean, new Dx who make insulin

14

stop these DMII meds if creatinine hits 1.5

metformin
DPP4

15

SGLT2 DMII treatment-action and AE

causes kidney to dump glucose into urine
good for weight loss, lowest mortality esp cardiac
AE: UTI

16

when picking oral hypoglycemic, consider (3)

renal function
cost
patient willingness, adherence

17

pt with anxiety and insomnia, use

a sedating SSRI (paxil, prozac)

18

2nd gen antipsychotic benefit

treats negative symptoms as well as positive

19

muscarinic antagonists may offer same benefit as

beta 2 agonists

20

norepinephrine causes release of

renin

21

anticoagulants in pregnancy

heparin- yes
warfarin - no

22

off switch of coagulation cascade

antithrombin III-protease that inhibits thrombin