pharma of diuretics Flashcards

1
Q

Acetazolamide is a …. diuretic?

a. loop
b. thiazide
c. osmotic
d. CA inhibitor
e. k sparring

A

CA inhib

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2
Q

Which works on PCT? 2

a. Thiazide
b. Loop
c. Osmotic
d. K-Sparing
e. CA inhib

A

CA inhib and Osmotic

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3
Q
Which work on PCT? 2
Acetazolamide
Furosemide
Chlorthalidone
Mannitol
Amiloride
Triamterene
A

acetazolamide and mannitol

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4
Q
Which inhibits carbonic anhydrase? 
Furosemide
Chlorthalidone
Mannitol
Acetazolamide
Amiloride
Triamterene
A

acetazolamide

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5
Q
Treatment of Glaucoma? 2
Mannitol
Furosemide
Chlorthalidone
Amiloride
Acetazolamide
Triamterene
A

acetazolamide and mannitol

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6
Q
Which drugs cause hypokalemia? 5
Acetazolamide
Hydrochlorothiazide
Furosemide
Ethacrynic Acid
Chlorthalidone
Mannitol
Spironolactone
Amiloride
Eplerenone
Triamterene
A
Hydrochlorothiazide
Chlorthalidone
Furosemide
Ethacrynic Acid
Acetazolamide
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7
Q
Which drugs cause hyperkalemia? 4
Eplerenone
Acetazolamide
Hydrochlorothiazide
Furosemide
Amiloride
Ethacrynic Acid
Mannitol
Spironolactone
Triamterene
Chlorthalidone
A

Eplerenone
Amiloride
Spironolactone
Triamterene

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8
Q
Which work on Loop of Henle? 2
Mannitol
Furosemide
Amiloride
Triamterene
Ethacrynic Acid
Chlorthalidone
Spironolactone
A

Ethacrynic Acid

Furosemide

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9
Q
Inhibit NKCC? 2
Acetazolamide
Furosemide
Chlorthalidone
Ethacrynic Acid
Amiloride
Triamterene
A

Ethacrynic Acid

Furosemide

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10
Q
May precipitate gout? 4
Chlorthalidone
Furosemide
Spironolactone
Eplerenone
Hydrochlorothiazide
Ethacrynic Acid
Triamterene
Mannitol
A

Ethacrynic Acid
Furosemide
Chlorthalidone
Hydrochlorothiazide

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11
Q

May precipitate gout? 2

a. Thiazide
b. Loop
c. Osmotic
d. K-Sparing
e. CA inhib

A

a. Thiazide

b. Loop

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12
Q

Drugs of choice for reducing acute pulmonary edema and peripheral edema caused by heart failure or renal impairment?

a. Thiazide
b. Loop
c. Osmotic
d. K-Sparing
e. CA inhib

A

loop

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13
Q

Drugs of choice for reducing acute pulmonary edema and peripheral edema caused by heart failure or renal impairment?

a. Hydrochlorothiazide
b. Furosemide
c. Mannitol
d. Amiloride
e. Eplerenone

A

Furosemide (Ethacrynic Acid too)

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14
Q
SE: ototoxicity?
Acetazolamide
Ethacrynic Acid
Chlorthalidone
Mannitol
Amiloride
Triamterene
A

Ethacrynic Acid (Furosemide too)

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15
Q

Have the greatest efficacy?

a. Thiazide
b. Loop
c. Osmotic
d. K-Sparing
e. CA inhib

A

loop

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16
Q
Have the greatest efficacy?
Acetazolamide
Spironolactone
Ethacrynic Acid
Hydrochlorothiazide
A

Ethacrynic Acid (Furosemide too)

17
Q
Which work on early DCT?
Acetazolamide
Hydrochlorothiazide
Furosemide
Ethacrynic Acid
Chlorthalidone
Mannitol
Spironolactone
Amiloride
Eplerenone
Triamterene
A

Hydrochlorothiazide

Chlorthalidone

18
Q
Inhibit NCC?
Mannitol
Furosemide
Amiloride
Ethacrynic Acid
Chlorthalidone
Spironolactone
A

Chlorthalidone (Hydrochlorothiazide too)

19
Q

For: HTN, diabetes insipidus, and calcium ox stones?

a. Thiazide
b. Loop
c. Osmotic
d. K-Sparing
e. CA inhib

A

Thiazide

20
Q

Most commonly used?

a. Thiazide
b. Loop
c. Osmotic
d. K-Sparing
e. CA inhib

A

Thiazide

21
Q
Most commonly used?
Acetazolamide
Spironolactone
Ethacrynic Acid
Hydrochlorothiazide
A

Hydrochlorothiazide (Chlorthalidone too)

22
Q
Which work on both late DT and CD? 2
Spironolactone
Furosemide
Eplerenone
Triamterene
Mannitol
Amiloride
A

Spironolactone

Eplerenone

23
Q
Which work only on CD? 2
Spironolactone
Furosemide
Eplerenone
Triamterene
Mannitol
Amiloride
A

Triamterene

Amiloride

24
Q
Inhibit ENaC? 2
Spironolactone
Furosemide
Eplerenone
Triamterene
Mannitol
Amiloride
A

Triamterene

Amiloride

25
Q
Reduce Na/H exchange? 2
Spironolactone
Furosemide
Eplerenone
Triamterene
Mannitol
Amiloride
A

Triamterene

Amiloride

26
Q
Non-selective aldosterone receptor antagonist?
Spironolactone
Furosemide
Eplerenone
Triamterene
Mannitol
Amiloride
A

Spironolactone

27
Q
Selective mineralocorticoid receptor antagonist?
Spironolactone
Furosemide
Eplerenone
Triamterene
Mannitol
Amiloride
A

Eplerenone

28
Q
First-line treatment of HTN secondary to MI?
Spironolactone
Furosemide
Eplerenone
Triamterene
Mannitol
Amiloride
A

Eplerenone