Pharmacodynamics

Question 1

pharmacodynamics means

Answer 1

the drugs power or force

Question 2

what does dose response relationship mean

Answer 2

relationship between the SIZE of an administered dose and the INTENSITY of the response produced

Question 3

dose response relationship determines

relative potency

maximum efficacy

Answer 3

relative potency
- minimum amount of drug needed to elicit a response

maximum efficacy
- maximum response a drug can elicit

Question 4

Drug - Drug interactions 3 possible outcomes

potentiate

inhibit

new response

Answer 4

potentiate
- intensifies the effects

inhibit
- reduce the effects

new response
- effect not seen with single drug alone

Question 5

drug food interactions

drug vs food:

Answer 5

absorption
drug metabolism
drug toxicity
drug action
timing

Question 6

Therapeutic Index

TI = LD50/ ED50

Answer 6

TI = therapeutic index
LD = lethal dose
ED = therapeutic dose