Pharmacodynamics

Question 1

Selectivity

Answer 1

Ability of a drug to specifically target certain biological pathways or receptors without affecting others.

Question 2

Affinity

Answer 2

Probability of a drug occupying a receptor. Can be impacted by both external and intracellular factors. Aging, genetics, and mutations can all impact affinity.

Question 3

Intrinsic efficacy

Answer 3

Extent to which a drug can activate a receptor and produce a maximal biological response.

Question 4

Residence time

Answer 4

Measure of how long the drug interacts with the body’s systems, which can influence its therapeutic effects and potential side effects

Question 5

Agonist

Answer 5

Bind to receptors and activate them to stimulate a desired cellular response.

Question 6

Antagonist

Answer 6

Binds to a receptor but does not activate it. Instead, it blocks the receptor, preventing other substances (like agonists) from binding and triggering a response.

Question 7

Pharmacokinetics

Answer 7

Study of how drugs are absorbed, distributed, metabolized, and excreted.