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Pharmacology Flashcards

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0
Q

Venous drainage for SUBLINGUAL ROUTE?

A

Lingual Vein -> Internal Jugular Vein -> Brachiocephalic (Innominate) Vein -> Superior Vena Cava -> Right Atrium
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

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1
Q

Drugs that induce AGRANULOCYTOSIS?

A 
Clozapine
Cotrimoxazole
Colchicine
Aminopyrine
Phenylbutazone
PTU
Tocaimide
Indomethacin
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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2
Q

Drugs with NARROW therapeutic index?

A 
MNEMONICS:
WALA na Cyang PaPa! VasTeD na! 
----------------
Warfarin
Aminoglycoside
Lithium
Amphotericin B 
Carbamazepine
Phenobarbital
Phenytoin
Vancomycin
Theophylline
Digoxin
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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3
Q

Drugs that cause CUTANEOUS FLUSHING?

A 
MNEMONICS:
VANC
----------------
Vancomycin
Adenosine
Niacin
Calcium Channel Blockers
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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4
Q

Drugs that induce LUPUS?

A 
MNEMONICS:
HIPPP
----------------
Hydralazine
Isoniazid
Procainamide
Penicillamine
PTU
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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5
Q

Drugs causing GINGIVAL HYPERPLASIA?

A 
MNEMONICS:
NapaCa Pangit ng GingiVa mo!
----------------
Nifedipine
Cyclosporine
Phenytoin
Verapamil
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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6
Q

Drugs that cause ERECTILE DYSFUNCTION?

A 
MNEMONICS:
SORE PEniS can't Fuck Hard!
----------------
SSRI's
Optiates
Risperidone
Ethanol
Propanolol
Estrogen
Spironolactone
Finasteride
HCTZ
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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7
Q

Drugs that have ZERO ORDER KINETICS?

A 
MNEMONICS:
WHAT PET
----------------
Warfarin
Heparin
Aspirin
Tolbutamide
Phenytoin
Ethanol
Theophylline
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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8
Q

Drugs that cause DISULFIRAM REACTION?

A 
Chlorpropamide
Cefoperazone
Cefotetan
Cefomandole
Procarbazine
Metronidazole
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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9
Q

Drugs that are CP450 INDUCERS?

A 
MNEMONICS:
Ethel Booba take Phen-Phen and Refuses Greasy Carb ShakeS.
----------------
Ethanol
Barbiturates
Phenytoin
Phenobarbital
Rifampicin
Griseofulvin
Carbamazepine
St. John Wort
Smoke
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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10
Q

Drugs that are CP450 INHIBITORS?

A 
MNEMONICS:
Queen V's SICK RAGE
---------------- 
Quinidine
Valproic Acid
Sulfonamides
Isoniazid
Cimetidine
Ketoconazole
Ritonavir
Amiodarone
Grapefruit Juice
Erythromycin
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
Erythromycin
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11
Q

It is a sudden decrease in the response to a drug after its administration?

A

Tachyphylaxis
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

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12
Q

Drugs causing TACHYPHYLAXIS?

A 
Metoclopramide
Ephedrine
Dobutamine
Desmopressin
LSD
Calcitonin
Nitroglycerine
Nicotine
Hydralazine
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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13
Q

Treatment for ALCOHOLISM?

A 
Disulfiram
Acamprosate
Naltrexone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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14
Q

Drugs causing GYNECOMASTIA?

A 
MNEMONICS:
Some Drugs Create Awesome Knockers!
----------------
Spironolactone
Digoxin
Cimetidine
Alcohol
Ketoconazole
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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15
Q

Drugs that cause PRIAPISM?

A 
MNEMONICS:
Tigas PeniS Co, AyaW Bumaba!
----------------
Trazodone
Papaverine
Sildenafil
Quetiapine
Alprostadil
Warfarin
Bupropion
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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16
Q

Drugs that induce HYPERTHYROIDISM?

A 
Clofibrate
Amiodarone
Methadone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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17
Q

Drugs that induce PARKINSONISM?

A 
Reserpine
Typical Antipsychotics
Methylphenyltetrahydropyridine
                 (MTPT)
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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18
Q

Triad for BRONZE DIABETES (Hemochromatosis)?

A 
Diabetes Mellitus
Cirrhosis
Skin Pigmentation
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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19
Q

Treatment for HEMOCHROMATOSIS?

A 
Phlebotomy
Deferoxamine
Deferasirox
Deferiprone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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21
Q

Signs and symptoms for ORGANOPHOSPHATE POISONING?

A 
MNEMONICS:
DUMBBELSS
----------------
Diarrhea
Urination
Myosis
Bronchospasms
Bradycardia
Excitation
Lacrimation
Sweating
Salivation
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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22
Q

Toxic effects of AMIODARONE?

A 
Pulmonary Fibrosis
Paresthesia
Tremors
Thyroid Dysfunction
Corneal Deposits
Skin Deposits
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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23
Q

Andrenergic receptors and functions?

A 
Alpha 1 - vasoconstriction
Beta 1 - increase heart rate and    
              contractility
Beta 2 - vasodilation and 
              bronchodilation
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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24
Q

Serotonin Syndrome?

A 
MNEMONICS: 
FD CHAT
----------------
Fever
Diaphoresis
Clonus
Hyperreflexia
Agitation
Tremor
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
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25
Treatment for SEROTONIN SYNDROME?
Cyproheptadine __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
26
Antidote for ORGANOPHOSPHATE POISONING?
``` Pralidoxime - if within 6 hrs Atropine __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
27
It is an acute episode of DELIRIUM that is usually 48-72 hrs after withdrawal from ALCOHOL?
Delirium Tremens __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
28
Signs and symptoms of DELIRIUM TREMENS?
``` Hallucinations Autonomics Hyperactivity Delirium __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
29
Drug of choice for DELIRIUM TREMENS?
Benzodiazepines __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
30
Vitamin deficiency for Wernicke Korsakoff Syndrome?
Thiamine (Vit. B1) Deficiency __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
31
Wernicke Korsakoff Syndrome?
``` Ataxia Confusion Opthalmoplegia __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
32
It is a common skin finding consisting of a mottled reticulated vascular pattern that appears like a lace-like purplish discoloration of the skin?
Livedo Reticularis __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
33
Drugs causing LIVEDO RETICULARIS?
``` Amantadine Hydroxyurea Minocycline Gemcitabine Quinidine __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
34
Drugs effective at DECREASING TRIGLYCERIDES and VLDL and INCREASING HDL?
``` Niacin Fibrates __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
35
Drugs most effective at DECREASING LDL and CHOLESTEROL?
``` MNEMONICS: NERS ---------------- Niacin Ezetimibe Resins Statins __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
36
Potassium Sparing Diuretics?
``` MNEMONICS: K STAEs ---------------- Spironolactone Triamterene Amiloride Eplerenone __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
37
Side effects of THIAZIDE DIURETICS?
``` MNEMONICS: hyper GLUC ---------------- hyperGlycemia hyperLipidemia hyperUricemia hyperCalcemia __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
38
Side effects of LOOP DIURETICS?
``` MNEMONCS: OH DANG! --------------- Ototoxicity Hypokalemia Dehydration Allergy to sulfa drugs Nephritis Gout __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
39
Antibiotics that are BACTERIOSTATIC?
``` MNEMONIC: ECSTaTiC -------------- Erythromycin Clindamycin Sulfamethazole Trimetoprim Tetracycline Chloramphenicol __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
40
Extended Spectrum PENICILLINS coverage?
``` MNEMONICS: Penicillins HELPS kill Enterococci ---------------- H. influenzae E. coli L. monocytogenes P. mirabilis Salmonella Enterococci __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
41
Antibiotics that are BACTERICIDAL?
``` MNEMONICS: VAMPFire ---------------- Vancomycin Aminoglycosides Metronidazole Penicillins Flouroquinolones __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
42
Antibiotics that are PROTEIN SYNTHESIS INHIBITORS?
``` MNEMONICS: buy AT 30s, CELLS at 50s ---------------- 30s Aminoglycosides Tetracyclines 50s Chloramphenicol Erythromycin Lincosamides Linezolid Streptogramins __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
43
FUNGICIDAL Antifungals?
``` Amphotericin Nystatin Terbinafine __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
44
Antibiotics of LAST RESORT?
``` MNEMONICS: I AM your Last Shot at Victory ---------------- Imepenem Amikacin Meropenem Linezolid Streptogramins Vancomycin __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
45
Cephalosporins with ANTIPSEUDOMONAL ACTIVITY?
``` 3rd Ceftazidime Cefoperazone 4th Cefepime __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
46
Phase 1 Reactions?
``` MNEMONICS: a HORDe of reactions. ---------------- Hydrolysis Oxidation Reduction Deamination __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
47
Drug induced PULMONARY FIBROSIS?
``` Bleomycin Busulfan Bromocriptine Amiodarone Nitrofurantoin Methotrexate __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
48
Antidote for METHOTREXATE?
Leucoverin __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
49
Antidote for CYCLOPHOSPHAMIDE?
Mesna __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
50
Antidote for DOXORUBICIN?
Dexrazoxane __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
51
Antidote for CISPLATIN?
Amifostine __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
52
Cancer chemotherapy drugs acting on M PHASE?
``` Vinblastine Vincristine Paclitaxel __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
53
Cancer chemotherapy drugs acting on G2 PHASE?
Bleomycin __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
54
Chemotherapy regimen for HODGKIN'S LYMPHOMA?
``` MNEMONICS: MOPP(original) ABVD(current) ---------------- Mustargen Oncovin (Vincristine) Procarbazine Prednisone ``` ``` Adriamycin Bleomycin Vinblastine Dacarbazibe __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
55
Chemotherapy regimen for NON-HODGKINS LYMPHOMA?
``` MNEMONICS: CHOP ---------------- Cyclophosphaminde Hydroxydaunorubicin Oncovin (Vincristine) Prednisone __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
56
Drug induced PULMONARY FIBROSIS?
``` Bleomycin Busulfan Bromocriptine Amiodarone Nitrofurantoin Methotrexate __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
57
Antidote for METHOTREXATE?
Leucoverin __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
58
Antidote for CYCLOPHOSPHAMIDE?
Mesna __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
59
Antidote for DOXORUBICIN?
Dexrazoxane __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
60
Antidote for CISPLATIN?
Amifostine __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
61
Cancer chemotherapy drugs acting on M PHASE?
``` Vinblastine Vincristine Paclitaxel __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
62
Cancer chemotherapy drugs acting on G2 PHASE?
Bleomycin __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
63
Chemotherapy regimen for HODGKIN'S LYMPHOMA?
``` MNEMONICS: MOPP(original) ABVD(current) ---------------- Mustargen Oncovin (Vincristine) Procarbazine Prednisone ``` ``` Adriamycin Bleomycin Vinblastine Dacarbazibe __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
64
Chemotherapy regimen for NON-HODGKINS LYMPHOMA?
``` MNEMONICS: CHOP ---------------- Cyclophosphaminde Hydroxydaunorubicin Oncovin (Vincristine) Prednisone __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
65
Drug induced PULMONARY FIBROSIS?
``` Bleomycin Busulfan Bromocriptine Amiodarone Nitrofurantoin Methotrexate __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
66
Antidote for METHOTREXATE?
Leucoverin __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
67
Antidote for CYCLOPHOSPHAMIDE?
Mesna __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
68
Antidote for DOXORUBICIN?
Dexrazoxane __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
69
Antidote for CISPLATIN?
Amifostine __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
70
Cancer chemotherapy drugs acting on M PHASE?
``` Vinblastine Vincristine Paclitaxel __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
71
Cancer chemotherapy drugs acting on G2 PHASE?
Bleomycin __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D.
72
Chemotherapy regimen for HODGKIN'S LYMPHOMA?
``` MNEMONICS: MOPP(original) ABVD(current) ---------------- Mustargen Oncovin (Vincristine) Procarbazine Prednisone ``` ``` Adriamycin Bleomycin Vinblastine Dacarbazibe __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```
73
Chemotherapy regimen for NON-HODGKINS LYMPHOMA?
``` MNEMONICS: CHOP ---------------- Cyclophosphaminde Hydroxydaunorubicin Oncovin (Vincristine) Prednisone __________________ Jan Patrick Ng, M.D. Darleen Sy, M.D. ```

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