Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

AMK > Pharmacology > Flashcards

Pharmacology Flashcards

(83 cards)

Start Studying
1
Q

Sx paracetamol overdose

A

N+V, jaundice, RUQ pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Tx paracetamol overdose

A

Activated charcoal if within 1hr and then acetylcysteine if longer or if indicated by plasma paracetamol levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Opioid antidote

A

naloxone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Methanol antidote

A

Ethanol or fomepizole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Benzo antidote

A

Flumenazil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

TCA overdose antidote

A

Bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Aspirin overdose antidote

A

Bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

B Blockers antidote

A

Atropine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Ethylene glycol antidote

A

Fomepizole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Organophosphate antidote

A

Atropine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Reversing heparin

A

Protamine sulphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Reversing dabigatran

A

Idarucizumb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Reversing rivaroxaban

A

Andexanet alfa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Reversing apixaban

A

Andexanet alfa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ACEi MOA

A

Stops angiotensin conversion from 1-2 by inhibiting ACE enzyme
Angiotensin 2 is a vasoconstrictor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

S/e ACEi

A

Cough, hyperkalaemia, angioedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

B-blockers MOA

A

Antagonise B receptors = reduced BP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

C/I B blockers

A

Asthmatics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Side effects B blockers

A

Erectile dysfunction, psoriasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

CCB e.g.

A

Amlodipine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

CCB MOA

A

Calcium needed in cells for contraction - blocking this dilates arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

S/E CCB

A

Flushing, headache, ankle swelling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Furosemide s/e

A

Hypokalaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Spironolactone MOA

A

Aldosterone antagonist - increased sodium and water excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Spironolactone s/e
Hyperkalaemia and gynaecomastia
26
Antidepressant causing long QT
citalopram
27
Side effect of carbimazole
agranulocytosis
28
How does agranulocytosis present
Suppression of immune system - sore throat
29
What is carbimazole used for?
Grave's
30
quinolones and long QT
quinolones (anti-malarial) cause long QT which puts you at risk for ventricular fibrillation
31
cause of clubbing
inflammatory conditions like crohns
32
adverse effect of gentamicin
ototoxicity
33
B-lactam e.g.s
carbanepems, cephalosporins, penicillins
34
penicillin AMK relevance
anaphylactic allergy, Steven-johnson
35
cephalosporin e.g.
cefotaxime - GI upset
36
carbapenams e.g.
meropenam - GI upset
37
aminoglycosides MOA
30s ribosome - e.g. gentamicin
38
macrolides MOA
50s ribosome - clarithromycin and erythromycin
39
adverse effect macrolides
long QT -> torsades du pointes + hepatitis
40
tetracycline adverse effect
e.g. doxycycline - not under 12 because stains teeth
41
adverse effect chloramphenicol
don't give to pregnant women - grey-baby syndrome
42
glycopeptides e.g.
vancomycin - oto/renal toxicity
43
quinolone MOA and adverse effects
ciprofloxacin decrease seizure threshold, tendonitis, long QT
44
achilles tendonitis is caused by which antibiotic
ciprofloxacin
45
metronidazole adverse effect
metallic taste vomiting if taken with alcohol
46
colistin adverse effect
myasthenia graves
47
ethambutol side effect
optic neuritis
48
isoniazid side effect
peripheral neuropathy
49
pyroniazid side effect
gout
50
electrolyte imbalance SSRIs
low sodium
51
SSRI for paeds
fluoxetine
52
how long before SSRIs work
2 weeks
53
TCA overdose treatment
bicarbonate
53
TCA overdose treatment
bicarbonate
54
mirtazapine side effects
helps pt sleep and put on weight
55
typical antipsychotics side effects
hyperprolactinaemia
56
which atypical antipsychotic doesn't cause prolactinaemia
aripiprazole
57
EPSEs
pseudoparkinsonism, acute dystonia (grimacing, eye movements, laryngeal spasms), tardive dyskinesia (protrusion of tongue), akathisia (restlessness)
58
antiemetics for metabolic disturbance/chemo
metoclopramide haloperidol
59
when don't you give metoclopramide?
with cyclising to pt with parkinsons bowel obstruction
60
antiemetic for gastric stasis
metoclopramide domperidone
61
MOA metoclopramide and domperidone
D2 antagonist
62
antiemetic for raised ICP
cyclizine dexamethasone (mets)
63
antiemetic for movement-related sickness
cyclizine (anti-histamine)
64
antiemetics for oral irritation
treat reflux first, then cyclizine
65
broad spectrum antiemetic
levomepromazine
66
fear/anxiety induced nausea treatment
lorazepam
67
antiemetic for bowel obstruction
loperamide
68
antiemetic for post-surgery
ondansetron
69
biguianides e.g. and side effect
metformin, weight loss, lactic acidosis and not for eGFR <30
70
thiazolidinediones e.g. and side effect
pioglitazone, don't cause hypos but do cause weight gain, don't prescribe if in heart/liver failure
71
sulfonylureas e.g. and side effect
gliclazide causes hypoglycaemia and weight gain don't prescribe with BB, high BMI or cardio problems
72
GLP-1RA e.g. and side effect
dulaglutide no hypos and weight loss, but causes Pancreatitis
73
injection only diabetes medication
dulaglutide
74
DPP-4i e.g. and side effect
sitagliptin GI upset and pancreatitis
75
SGLT2i e.g. and side effect
dapagliflozin weight loss, decreases BP
76
which diabetes drugs cause pancreatitis
DPP-4i and GLP-1RA
77
loop diuretic e.g. and side effect
furosemide decreased sodium, potassium, calcium and magnesium postural hypotension and tinnitus
78
thiazide diuretics e.g. and side effect
bendrofluorothiazide decreases sodium and potassium postural hypotension
79
CI thiazide diuretic
gout - high urate
80
K+ sparing diuretics e.g. and side effect
spironolactone increases k+, gynaecomastia
81
CI K+ sparing diuretic
Addison's disease
82
blood results Addison's
high potassium , low sodium

AMK (33 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions