Pharmacology Flashcards Preview

Peds Boards Take 2 > Pharmacology > Flashcards

Flashcards in Pharmacology Deck (26):
1

What drugs have increased elimination when taking St John's Wort?

OPCs, Iron, Digoxin, Anticoagulants, Antiretrovirals

2

Advice to a patient taking both OCPs and St John's Wort

Use back up contraception

3

Contraindications to echinacea

patients on immunosuppressive drugs

4

Drugs that can interact with Ginseng

Anticoagulants, antiplatelet meds, steroids, hypoglycemics, diuretics

5

Contraindications to using valerian root

use of alcohol or other sedating drugs

6

Isotretinoin should be taken with....

fatty foods - because it is lipophilic

7

Griseofulvin should be taken with...

fatty foods - because it is lipophilic

8

Tetracycline and doxycycline should not be taken with...

dairy products

9

Cipro should not be taken with

dairy products

10

Drug interaction for cephalosporins

decreases bioavailability of calcium, magnesium, iron, or aluminum supplements

11

Drug interaction for fluoroquinolones

decreases bioavailability of calcium, magnesium, iron, or aluminum supplements

12

Drug interaction for erythromycin

reduces metabolism for (and increases levels of) theophylline, codeine, beta blockers, antidepressants, steroids, warfarin, and metronidazole.

13

Drug interaction for Cipro

reduces metabolism for (and increases levels of) theophylline, codeine, beta blockers, antidepressants, steroids, warfarin, and metronidazole.

14

Drug interaction for cimetidine

reduces metabolism for (and increases levels of) theophylline, codeine, beta blockers, antidepressants, steroids, warfarin, and metronidazole.

15

Drug interaction for omeprazole

reduces metabolism for (and increases levels of) theophylline, codeine, beta blockers, antidepressants, steroids, warfarin, and metronidazole.

16

Name four meds that induce hepatic enzymes and thereby decrease levels of other meds

Rifampin
Phenobarbital
Carbamazepine
Phenytoin

17

How many half lives does it take to achieve a steady state?

4-5

18

In a patient on digoxin, which meds should they avoid to prevent elevated levels?

Quinidine
Amiodarone

19

Drug reaction to Cefaclor

Serum Sickness: fever, swollen lymph nodes, joint pain, rash

20

If a child had a previous skin reaction to penicillin, what are the odds of a similar reaction to a cephalosporin?

Less than 10%

21

Side effects of beta blockers

Sexual dysfunction
Sleep disturbance
Bronchospasm (worse asthma)
Bradycardia/heart block

22

Mechanism of action for acetazolamide

Causes proximal tubule to decrease reuptake of bicarbonate

23

Dose related side effects of furosemide

ototoxicity
renal toxicity

24

What ions are "wasted" by furosemide?

Potassium and Hydrogen

25

Which ions are primarily lost with hydrochlorothiazide?

Sodium and chloride

26

What happens to sodium and potassium with spironolactone?

Sodium is excreted and potassium is spared