Pharmacology Flashcards

(49 cards)

1
Q

Bleomycin SE

A

Pulmonary fibrosis

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2
Q

Cyclophosphamide SE

A

Hemorrhagic cystitis

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3
Q

Isoniazid SE

A

Vit B6 deficiency, lupus-like syndrome, liver toxicity

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4
Q

Cyclosporine SE

A

Renal toxicity

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5
Q

ACE inhibitors SE

A

Cough; angioedema

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6
Q

Demeclocycline SE

A

Diabetes Insipidus

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7
Q

Sulfa drugs SE

A

Allergies, kernicterus in neonates

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8
Q

Halothane SE

A

Liver necrosis

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9
Q

Local anesthetic SE

A

Seizures

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10
Q

Phenytoin SE

A

Teratogen, folate deficiency, hirsutism

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11
Q

Vincristine SE

A

Peripheral neuropathy

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12
Q

Amiodarone SE

A

Thyroid dysfunction, pulmonary toxicity

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13
Q

Valproic acid SE

A

NTD in offspring

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14
Q

Thioridazine SE

A

Retinal deposits, cardiac toxicity

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15
Q

Vancomycin SE

A

Red man’s syndrome

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16
Q

Clofibrate SE

A

Increased GI neoplasms

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17
Q

Tetracyclines SE

A

Photosensitivity, teeth staining in children

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18
Q

Quinolones SE

A

Teratogens (cartilage damage)

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19
Q

Quinidine (Class 1A antiarrhythmic) SE

A

Cinchonism (HA, tinnitus, vertigo), thrombocytopenia, QT prolongation

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20
Q

Morphine SE

A

Sphincter of Oddi spasm

21
Q

Clindamycin SE

A

Pseudomembranous colitis

22
Q

Chloramphenicol SE

A

Aplastic anemia, gray-baby syndrome ( in premature infants b/c they lack liver UDP-glucuronyl transferase)

23
Q

Doxorubicin SE

A

Cardiomyopathy

24
Q

Busulfan SE

A

Pulmonary fibrosis

25
MOA inhibitors
Tyramine HTN crisis after eating cheeses or wine
26
Hydralazine SE
Lupus-like syndrome
27
Procainamide SE
Lupus-like syndrome
28
Minoxidil SE
Hirsutism
29
Chlorpropamide SE
SIADH
30
Oxytocin SE
SIADH
31
Opiates SE
SIADH
32
Didanosine SE
Pancreatitis, peripheral neuropathy
33
Halogen anesthesia SE
Malignant hyperthermia
34
Succinylcholine SE
Malignant hyperthermia
35
Zidovudine SE
Bone marrow suppression
36
Digitalis SE
GI disorders, vision changes, arrhythmias
37
SSRI SE
Anxiety, agitation, insomnia, sexual dysfunction
38
Warfarin SE
Necrosis, teratogen
39
Simvastatin SE
Liver and muscle toxicity
40
Ethambutol SE
Optic neuritis
41
Cisplatin SE
Nephrotoxicity
42
Methyldopa SE
Hemolytic anemia (Coombs test -positive)
43
Benzodiazepines antidote
Flumazenil
44
Beta blockers antidote
Glucagon
45
Cholinesterase inhibitors antidote
Atropine, pralidoxime
46
Copper or gold antidote
Penicillamine
47
Lead antidote
EDTA or succimer in children
48
Methanol or ethylene glycol antidote
Fomepizole or ethanol
49
Muscarinic blockers antidote
Physostigmine