Pharmacology Flashcards

1
Q

What is the formula for volume of distribution?

A
Vd = Q / C
Q = dose or load
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2
Q

What is the formula for clearance?

A

CL = UV / P

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3
Q

What is the pharmacokinetic equilibrium equation?

A

Ke = Vd / CL

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4
Q

What is the formula for half-life?

A

t1/2 = 0.7*Vd / CL

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5
Q

What is the formula for maintenance dose?

A
MD = C*CL*t / F
F = bioavailability
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6
Q

What is the equation for loading dose?

A

LD = C*Vd / F

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7
Q

Which class of diuretics causes nephrolithiasis?

A

Loop diuretics

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8
Q

Which diuretic alters sex hormone regulation?

A

spironolactone

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9
Q

Which drug inhibits carbonic anhydrase?

A

acetazolamide

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10
Q

Which drug acts as an osmotic diuretic?

A

mannitol

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11
Q

What are the ACE inhibitors?

A

lisinopril, enalapril, captopril, ramopril

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12
Q

What are the ARBs?

A

losartan, valsartan, candesartan, irbesartan

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13
Q

What are the loop diuretics?

A

furosemide, torsemide, bumetanide, ethacrynic acid

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14
Q

What are the thiazides?

A

HCTZ, chlorthalidone, metolazone

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15
Q

What are the aldosterone antagonists?

A

spironolactone, eplerenone

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