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Flashcards in Pharmacology Deck (15):
1

Signs of Digitalis Toxicity


N/V, drowsiness, SVT, AV block, sinus bradycardia

2


What increased digoxin toxicity?


Hypokalemia, hypocalcemia, renal disease, hypoxia

3


What do ACE inhibitors do to hemodynamics?


Reduce afterload and attenuate neurohormonal effects of heart failure. Do not use in HCOM or Aortic stenosis

4


Advair


Fluticasone/Salmetarol - dose 100/50, 250/50, 500/50

 

5


Flovent


fluticasone Diskus: 50mcg, 100mcg, 250mcg

HFA: 44, 110, 220mcg

6


Omalizumab


Selective anti-immunoglobulin E therapy - humanised monoclonal antibody against IGe. Subq injection every 2-4 weeks. Indicated for pts>12 with steroid dependent asthma and allergies confirmed by skin testing.

7

Dose of zantac IV for peds

 

0.1mg/kg/d IV

8

What effects does methotrexate have when taken in pregnancy?

When taken between weeks 6-9 causes increased risk of craniosynotosis, craniofacial abnormalities, limb defects

9

What can use of ACE inhibitors during pregnancy cause?

 

renal dysgenesis, oligohydramnios, skull ossification defects

10

What does use of phenytoin during 1st trimester cause?

 

10% risk of fetal hydantoin syndrome - growth deficiency, devo delay, craniofacial abnormalities, hypoplastic phalanges/nails, also can have vitamin K deficiency

11

What effects do retinoic acid cause in utero?

 

Similar to DiGeorge syndrome

12

What effect does tetracycline have in utero?

 

increased risk of spina bifida and craniofacial defects

13

What effects does warfarin have in utero?

 

nasal hypoplasia and stipple epiphyses

14

What effects can Mercury have on the fetus?

 

cerebral atrophy, seizures, and devo delay

15