Signs of Digitalis Toxicity
N/V, drowsiness, SVT, AV block, sinus bradycardia
What increased digoxin toxicity?
Hypokalemia, hypocalcemia, renal disease, hypoxia
What do ACE inhibitors do to hemodynamics?
Reduce afterload and attenuate neurohormonal effects of heart failure. Do not use in HCOM or Aortic stenosis
Fluticasone/Salmetarol - dose 100/50, 250/50, 500/50
fluticasone Diskus: 50mcg, 100mcg, 250mcg
HFA: 44, 110, 220mcg
Selective anti-immunoglobulin E therapy - humanised monoclonal antibody against IGe. Subq injection every 2-4 weeks. Indicated for pts>12 with steroid dependent asthma and allergies confirmed by skin testing.
Dose of zantac IV for peds
What effects does methotrexate have when taken in pregnancy?
When taken between weeks 6-9 causes increased risk of craniosynotosis, craniofacial abnormalities, limb defects
What can use of ACE inhibitors during pregnancy cause?
renal dysgenesis, oligohydramnios, skull ossification defects
What does use of phenytoin during 1st trimester cause?
10% risk of fetal hydantoin syndrome - growth deficiency, devo delay, craniofacial abnormalities, hypoplastic phalanges/nails, also can have vitamin K deficiency
What effects do retinoic acid cause in utero?
Similar to DiGeorge syndrome
What effect does tetracycline have in utero?
increased risk of spina bifida and craniofacial defects
What effects does warfarin have in utero?
nasal hypoplasia and stipple epiphyses
What effects can Mercury have on the fetus?
cerebral atrophy, seizures, and devo delay