pharmacology for copd

Question 1

a. Antibiotic therapy increases cure rate and decreases clinical failure rate for?

Answer 1

COPD

Question 2

b._______ corticosteroid therapy improves dyspnea and reduces clinical failure rate FOR COPD

Answer 2

Systemic

Question 3

c. _____oxygen reduces mortality when compared to high flow oxygen FOR COPD

Answer 3

Titrated

Question 4

d. ______ training improves dyspnea and quality of life for copd

Answer 4

Resistance

Question 5

e. Early ______ initiated during hospitalization improves dyspnea

Answer 5

pulmonary rehabilitation

Question 6

a. 5-7 day course of antibiotics and systemic corticosterioids with titrating oxygen therapy to maintain saturations of ______ for adults with COPD exacerbation

Answer 6

88-92%

Question 7

1. Oxygen supplementation
2. Bronchodilators
3. Corticosteroids
4. Antibiotics
5. PRN ventilatory assistance with noninvasive ventilation OR intubated and ventilation

Answer 7

a. Treatment of acute COPD exacerbations should include

Question 8

1. Ensure adequate oxygenation and near normal pH, reverse airway obstruction, treat cause

Answer 8

goal for acute copd exacerbation

Question 9

what beta agonists are used for rapid brochodilation for copd?

Answer 9

albuterol by nebulizer

Question 10

what anticholinergics are given with to help treat copd?

Answer 10

ipratropium (a bronchodilator)

Question 11

What corticosteroids are used to reduce inflammation for copd?

Answer 11

prednisone PO

or

methylprednisolone IV

Question 12

when are antibiotics used for copd?

Answer 12

purulent sputum, chest x-ray abnormalities, positive cultures

Question 13

Eg. Trimethoprim/sulfamethoxazole, amoxicillin, doxycycline, azithromycin

Answer 13

antibiotics that can be used for copd

Question 14

prevent exacerbations and improve lung function

Answer 14

goal for treatment of stable copd

Question 15

1. Smoking cessation
2. Drug therapy
3. Oxygen therapy
4. Enhancement of nutrition
5. Pulmonary rehab

Answer 15

treatment for stable copd

Question 16

1. Beta -agonists and anticholinergics = inhaled bronchodilators
2. Inhaled corticosteroid to reduce airway inflammation
3. Theophylline (not often used anymore) – decreases smooth muscle spasm
4. Phosphodiesterase-4 inhibitor – fewer side effects than theophylline = has anti-inflammatory and mild bronchodilating properties
5. Macrolide antibiotic (azithromycin)

Answer 16

medications for stable copd

Question 17

1. Beta-agonists (eg. Albuterol by nebulizer) – rapid bronchodilation
2. Anticholinergics (eg. Ipratropium) – to be given concurrently with or alternating with beta-agonists by nebulizer or inhaler, also a bronchodilator
3. Corticosteroids (eg. Prednisone po OR methylprednisolone IV)
4. Antibiotics if have purulent sputum, chest x-ray abnormalities, positive cultures

Answer 17

medications for acute copd exacerbation