Pharmacology - general Flashcards

(428 cards)

1
Q

List adrenergic receptors

A

λ1, λ2, β1, β2, β3

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2
Q

λ1 receptors functions

A

–> in skin, sphincter of GI, kidneys, brain
–> contraction of smooth m of blood vessel
–> anorexia
–> mydriasis
–> + inotropic effect

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3
Q

λ2 receptors functions

A

–> in CNS, vascular smooth m.
–> inhibit release of noradrenaline
–> platelet aggregation
–> reduce salivation

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4
Q

β1 receptors functions

A

–> increase cardiac output
–> + chronotropic effect
–> + inotropic effect
–> renin release
–> lipolysis in adipose tissue

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5
Q

β2 receptors functions

A

–> resp, uterine, GI smooth m. relaxation
–> Increase blood flow in target organs
–> increase aqueous humor secretion
–> glycogenolysis and gluconeogenesis in liver

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6
Q

β3 receptors functions

A

–> gall bladder, urinary, fat
–> lipolysis in adipose tissue
–> thermogenesis in skeletal m.

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7
Q

Ephedrine

A

–> Sympathomimetic, non-catecholamine
–> hypertension
–> mydriasis
–> vasoconstriction (kidneys, mesenteric, skin)
–> For urinary incontinence
–> Decongestant

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8
Q

Amphetamine

A

–> Sympathomimetic, non-catecholamine
–> release noradrenaline

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9
Q

Phenylephrine

A

–> Sympathomimetic, non-catecholamine
–> peripheral vasoconstriction
–> Decongestant

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10
Q

Metoxamin
Metaramiol

A

–> Sympathomimetic, non-catecholamine
–> peripheral vasoconstriction

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11
Q

Ergometrine

A

–> Non selective λ adrenergic blocking agent
–> decrease vasoconstriction
–> treat perivascular spasm
–> anti-hypertensive
–> use in visceral ischemia
–> relaxation of 3rd eyelid

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12
Q

Phenoxibenzamine

A

–> Non selective λ adrenergic blocking agent
–> decrease vasoconstriction
–> treat perivascular spasm
–> anti-hypertensive
–> use in visceral ischemia
–> relaxation of 3rd eyelid

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13
Q

Dibenamine

A

–> Non selective λ adrenergic blocking agent
–> decrease vasoconstriction
–> treat perivascular spasm
–> anti-hypertensive
–> use in visceral ischemia
–> relaxation of 3rd eyelid

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14
Q

Phentolamine

A

–> Non selective λ adrenergic blocking agent
–> decrease vasoconstriction
–> treat perivascular spasm
–> anti-hypertensive
–> use in visceral ischemia
–> relaxation of 3rd eyelid

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15
Q

Talazoline

A

–> Non selective λ adrenergic blocking agent
–> decrease vasoconstriction
–> treat perivascular spasm
–> anti-hypertensive
–> use in visceral ischemia
–> relaxation of 3rd eyelid
–> Analeptic

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16
Q

Piperaxane

A

–> Non selective λ adrenergic blocking agent
–> decrease vasoconstriction
–> treat perivascular spasm
–> anti-hypertensive
–> use in visceral ischemia
–> relaxation of 3rd eyelid

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17
Q

Phenothiazine

A

–> Non selective λ adrenergic blocking agent
–> decrease vasoconstriction
–> treat perivascular spasm
–> anti-hypertensive
–> use in visceral ischemia
–> relaxation of 3rd eyelid

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18
Q

Chlorpromazine

A

–> Non selective λ adrenergic blocking agent
–> decrease vasoconstriction
–> treat perivascular spasm
–> anti-hypertensive
–> use in visceral ischemia
–> relaxation of 3rd eyelid
–> Tranquilizers, phenothiazine derivates
–> block dopamine effects
–> Antipsychotics
–> Serotonin antagonist
–> Anti-emetic

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19
Q

Prazosine

A

–> Selective λ1 adrenergic blocking agent
–> anti-hypertensive
–> Peripheral vasodilator
–> use to reduce effect of heart failure

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20
Q

Trimazosine

A

–> Selective λ1 adrenergic blocking agent
–> Anti-hypertensive

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21
Q

Atipamezole

A

–> Selective λ2 adrenergic blocking agent
–> Tranquilizers

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22
Q

Yohimbine

A

–> Selective λ2 adrenergic blocking agent
–> Tranquilizers, sedation, analgesia

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23
Q

Propanolol

A

–> Non selective β adrenergic blocking agent
–> anti-arrythmic
–> anti-hypertensive
–> obstructive heart disease
–> use in myocardial infarct risk

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24
Q

Pronethalol

A

–> Non selective β adrenergic blocking agent
–> anti-arrythmic
–> anti-hypertensive
–> obstructive heart disease
–> use in myocardial infarct risk

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25
Sotalol
--> Non selective β adrenergic blocking agent --> anti-arrythmic --> anti-hypertensive --> obstructive heart disease --> use in myocardial infarct risk
26
Atenolol
--> Selective β1 adrenergic blocking agent --> use in hypertension, arrhythmia
27
Metoprolol
--> Selective β1 adrenergic blocking agent --> use in hypertension, arrhythmia
28
Butoxamine
--> Selective β2 adrenergic blocking agent --> use in hypertension, arrhythmia
29
Esters of choline
--> parasympathomimetic direct acting agent
30
Acetylcholine
--> parasympathomimetic direct acting agent
31
Metacoline
--> parasympathomimetic direct acting agent
32
Carbachol
--> parasympathomimetic direct acting agent --> Purgative (irritant)
33
Betanecol
--> parasympathomimetic direct acting agent
34
Pilocarpine
--> parasympathomimetic natural alkaloid cholinomimetic --> Emetic
35
Muscarine
--> parasympathomimetic natural alkaloid cholinomimetic
36
Physostigmine
--> parasympathomimetic indirect acting agent, cholinesterase inhibitors --> antidote : atropine --> Purgative (irritant)
37
Neostigmine
--> parasympathomimetic indirect acting agent, cholinesterase inhibitors --> antidote : atropine --> Purgative (irritant)
38
Atropine
--> parasympatholytic --> serotonin antagonist --> Anti-diarrheal
39
Scopolamine
--> parasympatholytic --> Anti-emetic (not in cat)
40
Glycopyrrolate
--> parasympatholytic --> Anti-emetic --> Anti-ulcer --> Anti-diarrheal --> Bronchodilators
41
Homatropine
--> parasympatholytic
42
Propantheline
--> parasympatholytic --> Anti-diarrheal
43
Methylatropine
--> parasympatholytic
44
Isoflurane
--> Inhaled anesthetics
45
Sevoflurane
--> Inhaled anesthetics
46
Halothane
--> Inhaled anesthetics
47
Propofol
--> Injectable anesthetics --> induction --> short acting
48
Etomidate
--> Injectable anesthetics --> hypnotic, very short action
49
Metomidate
--> Injectable anesthetics --> sedative, hypnotic
50
Chloral-hydrate
--> Injectable anesthetics --> Euthanizing agents
51
Magnesium sulphate
--> Injectable anesthetics --> Anti-arrhythmia --> use for ventricular tachycardia --> Anti-ulcer --> Purgative
52
Guaifenesin
--> Injectable anesthetics
53
Altesin (alfaxalone, alfadolone)
--> Injectable anesthetics --> rapid action
54
Phencyclidine
--> Injectable anesthetics
55
Ketamine
--> Injectable anesthetics --> max 30min --> analgesic --> don't use with head injury and glaucoma
56
Tiletamine
--> Injectable anesthetics
57
Chloralose
--> Injectable anesthetics
58
Phenobarbital
--> Injectable anesthetics, barbiturate --> anticonvulsant --> Euthanizing agents
59
Pentobarbital
--> Injectable anesthetics, barbiturate --> Anticonvulsant, control severe seizures --> Euthanizing agents
60
Thiopental
--> Injectable anesthetics, barbiturate --> for induction or short action --> Euthanizing agents
61
Morphine
--> Opioid --> emesis
62
Codeine phosphate
--> Opioid --> constipation
63
Hydromorphone
--> Opioid
64
Oxymorphone
--> Opioid
65
Meperidine
--> Opioid
66
Fentanyl
--> Opioid
67
Naloxone
--> Opioid antagonist
68
Naltrexone
--> Opioid antagonist
69
Nalbuphrine
--> Opioid antagonist
70
Diprenorphine
--> Opioid antagonist
71
Promazine
--> Tranquilizers, phenothiazine derivates --> block dopamine effects --> Antipsychotics
72
Acepromazine
--> Tranquilizers, phenothiazine derivates --> block dopamine effects --> Antipsychotics
73
Prochlorperazine
--> Tranquilizers, phenothiazine derivates --> block dopamine effects --> Antipsychotics --> Anti-emetic
74
Trimeprazine
--> Tranquilizers, phenothiazine derivates --> block dopamine effects --> Antipsychotics --> Anti H1
75
Diazepam
--> Tranquilizers, benzodiazepine derivates --> Anticonvulsant --> Anxiolytics --> Appetite stimulant (cat)
76
Midazolam
--> Tranquilizers, benzodiazepine derivates
77
Clordiazepoxid
--> Tranquilizers, benzodiazepine derivates
78
Flumazenil
--> benzodiazepine competitive ANTAGONIST
79
Droperidol
--> Tranquilizers, butyrophenone derivates --> first choice in emergency traumatic shock --> Anti-emetic
80
Haloperidol
--> Tranquilizers, butyrophenone derivates --> Antipsychotics --> Anti-emetic
81
Azaperona
--> Tranquilizers, butyrophenone derivates
82
Xylazine
--> Tranquilizers, λ2 adrenergic agonist --> Emetic
83
Detomidin
--> Tranquilizers, λ2 adrenergic agonist
84
Medetomidine
--> Tranquilizers, λ2 adrenergic agonist
85
Romifidin
--> Tranquilizers, λ2 adrenergic agonist --> in horse
86
Tolazoline
--> Tranquilizers, λ2 adrenergic agonist
87
Procaine
--> Local anesthetics
88
Chlorprocaine
--> Local anesthetics
89
Tetracaine
--> Local anesthetics
90
Bupivacaine
--> Local anesthetics
91
Etidocaine
--> Local anesthetics
92
Lidocaine
--> Local anesthetics --> Anti-arrythmic --> ventricular anti-arrhythmic
93
Ropivacaine
--> Local anesthetics
94
Mepivacaine
--> Local anesthetics
95
Imepitoin
--> Anticonvulsant --> in dogs
96
Potassium bromide
--> Anticonvulsant
97
Primidone
--> Anticonvulsant
98
Phenytoin
--> Anticonvulsant --> Anti-arrythmic --> use for ventricular arrhythmia
99
What's an analeptic
CNS stimulant
100
Doxapram
--> Analeptic (resp stimulant)
101
Methylxanthine derivates (caffeine, theophylline, theobromine)
--> Analeptic
102
Lorazepam
--> Anxiolytic
103
Oxazepam
--> Anxiolytic --> Appetite stimulant (cat)f
104
Imipramine
--> Antidepressant
105
Clomipramine
--> Antidepressant
106
Doxepine
--> Antidepressant
107
Selegiline
--> Antidepressant --> Hyperadrenocorticism
108
Fluoxetine
--> Antidepressant
109
Citaloprame
--> Antidepressant
110
Venlafaxine
--> Antidepressant
111
Mirtazapine
--> Antidepressant --> Appetite stimulant
112
Ethanole
--> Euthanizing agents
113
T61
--> Euthanizing agents
114
What's an autacoid ?
Substance produced by an organism that has a local action on cells or tissues nearby
115
Histamine roles
--> GI : Stimulate HCl secretion --> Circulatory system : regulate microcirculation in response to tissue damage and inflammation
116
Histamine receptors roles
H1 : smooth m. contraction, pruritus, prostaglandin generation H2 : HCl secretion H3 : modulate histamine release H4 : on WBC
117
Diphenhydramine
--> Anti H1 --> Anti-emetic --> Decongestant
118
Pyrilamine
--> Anti H1
119
Tripelenamine
--> Anti H1
120
Clorpheniramine
--> Anti H1
121
Dimenhydrinate
--> Anti H1 --> Decongestant
122
Promethazine
--> Anti H1
123
Clemastine
--> Anti H1
124
Hydroxyzine
--> Anti H1 --> Decongestant
125
Astemizole
--> Anti H1
126
Terfenadine
--> Anti H1
127
Amitriptyline
--> Anti H1
128
Cimetidine
--> Anti H2 --> Anti-ulcer
129
Famotidine
--> Anti H2 --> Anti-ulcer
130
Ranitidine
--> Anti H2 --> Anti-ulcer
131
Nizatidine
--> Anti H2 --> Anti-ulcer
132
Serotonin roles
--> contraction of bv --> neurotransmitter --> sleep --> behavior --> Appetite stimulant --> thermoregulation
133
Metoclopramide
--> Anti-emetic --> Appetite stimulant --> Stimulator of gastric motility
134
Ondansetron
--> Anti-emetic
135
Ketanserin
--> treatment of wound, prevent keloid formation --> anti-serotonin
136
Angiotensin role
Increase BP
137
Saralsin
--> Anti-angiotensin
138
Captopril
--> Anti-angiotensin --> Vasodilatation (inhibitors of phosphodiesterase) --> + inotropic effect
139
Enalapril
--> Anti-angiotensin --> Vasodilatation (inhibitors of phosphodiesterase) --> + inotropic effect
140
Prostaglandin effects
--> Cardiovascular syst : smooth m. contraction --> Blood : clotting factors --> Renal syst : vasodilatation, increase excretion of Na, K, Cl, water
141
Cytokine : list and roles
TNF-λ : mediator of endotoxic shock Interleukin : mediate natural immune response and proliferation of Ab synthesis Interferons : affect viral DNA and RNA replication
142
Salicyclic acid
--> Analgesic --> Anti-inflammatory --> Antipyretic
143
Antipyretic def
Drug to prevent/reduce fever
144
Celecoxib
--> NSAID
145
Meloxicam
--> NSAID
146
Diclofenac
--> NSAID
147
Pyroxicam
--> NSAID --> Hormone antitumor therapy (only palliative)
148
Ibuprofen
--> NSAID
149
Naproxen
--> NSAID
150
Ketoprofen
--> NSAID
151
Phenylbutazone
--> NSAID --> Cats are sensitive
152
Carprofen
--> NSAID
153
Flunixin meglumin
--> NSAID
154
Mavacoxib Enflicoxib
--> NSAID --> for osteoarthritis
155
Metamizole
--> analgesic --> anti-pyretic
156
Bedinvetmab
--> analgesic --> for osteoarthritis
157
Digitoxine
--> Vasodilatation (natural) --> use for heart failure, arrhythmia
158
Gitaline
--> Vasodilatation (natural) --> use for heart failure, arrhythmia
159
Gitoxine
--> Vasodilatation (natural) --> use for heart failure, arrhythmia
160
Digoxine
--> Vasodilatation (natural) --> use for heart failure, arrhythmia
161
Amrinone
--> Vasodilatation (inhibitors of phosphodiesterase) --> + inotropic effect
162
Milrinone
--> Vasodilatation (inhibitors of phosphodiesterase) --> + inotropic effect
163
Imidarone
--> Vasodilatation (inhibitors of phosphodiesterase) --> + inotropic effect
164
Pimobendane
--> Vasodilatation (inhibitors of phosphodiesterase) --> + inotropic effect
165
Hydralazine
--> Vasodilatation (inhibitors of phosphodiesterase) --> + inotropic effect
166
Benazepril
--> Vasodilatation (inhibitors of phosphodiesterase) --> + inotropic effect
167
Amlopidine
--> Vasodilatation (inhibitors of phosphodiesterase) --> + inotropic effect
168
Ancillary therapy in heart failure
--> Oxygen demands --> Diuretics --> Morphine --> Aminophilline (bronchodilator)
169
Quinidine
--> Anti-arrythmic --> use for atrial fibrillation
170
Procainamide
--> Anti-arrythmic --> use for ventricular arrhythmia
171
Oxprenolol
--> Anti-arrythmic --> use for atrial fibrillation
172
Alprenolol
--> Anti-arrythmic --> use for atrial fibrillation
173
Labetalol
--> Anti-arrythmic --> use for atrial fibrillation
174
Bretylium
--> Anti-arrythmic --> use for ventricular arrhythmia
175
Amiodaron
--> Anti-arrythmic --> use for ventricular arrhythmia
176
Verapamil
--> Anti-arrythmic --> use for tachycardia and atrial fibrillation
177
Adenosine
--> Anti-arrythmic
178
When do you use Ringer's lactate solution ?
Mild acidosis (not in severe) Extracellular dehydration Hypovolemia peri-op Hemorrhagic chock
179
Ringer lactate contre-indication
Cardiac insufficiency Hypercalcemia Hyperkalemia Metabolic alkalosis Severe metabolic acidosis Hepatic insufficiency Hypernatremia
180
List of crystalloids substances
Ringer's solution Ringer's lactate solution Normal saline Dextrose
181
List of colloids substances
Whole blood Plasma Albumin Dextran 40 or 70 Hetastarch or pentastarch Oxypolygelatin
182
Phenylpropanolamine
--> For urinary incontinence
183
Estriol
--> For urinary incontinence
184
Propantheline
--> For urinary incontinence
185
Allopurinol
--> For renal lithiasis
186
Probenecid
--> For renal lithiasis
187
Penicillamine
--> For renal lithiasis
188
Potassium citrate
--> For renal lithiasis --> prevent calcium oxalate and uric urolithiasis
189
Methionine
--> For renal lithiasis --> prevent struvites --> Liver protectant (protect from toxin)
190
Mannitol
--> Diuretic --> Purgative
191
Furosemide
--> Diuretic
192
Acetazolamide
--> Diuretic
193
Dichlorphenamide
--> Diuretic
194
Methazolamide
--> Diuretic
195
Dorzolamide
--> Diuretic
196
Glycerin
--> Diuretic
197
Urea
--> Diuretic (osmotic)
198
Ethacrynic acid
--> Diuretic
199
Bumetanide
--> Diuretic
200
Torsemide
--> Diuretic
201
Chlorothiazide
--> Diuretic
202
Hydrochlorothiazide
--> Diuretic
203
Cyclothiazide
--> Diuretic
204
Methychlothiazide
--> Diuretic
205
Triamterene
--> Diuretic
206
Amiloride
--> Diuretic
207
Spironolactone
--> Diuretic
208
Canrenone
--> Diuretic
209
Conivaptan
--> Diuretic
210
Tolvaptan
--> Diuretic
211
Demeclocytine
--> Diuretic
212
Lithium
--> Diuretic
213
What do you give in case of acute hemorrhage ?
Whole blood Crystalloid solution : - 0.9% saline sol + 6-10% dextran 40 or 70 - dextran 70 - pentastarch - hetastarch
214
What do you do in case of chronic hemorrhage ?
- whole blood transfusion - blood products - adequate nutrition - iron therapy
215
What do you do in case of anemia in newborn piglet ?
i.m. on the 2nd or 3rd day of life --> iron dextran
216
What do you do in case of hemolytic anemia ?
- whole blood transfusion - crystalloid substances vitamins with antioxidant properties (A, E, C)
217
What do you do in case of hypoplastic anemia (immune-mediated) ?
- endocrinopathies (hypothyroidism, hyperestrogenism) - lithium carbonate : improve hematopoiesis
218
Thrombin
--> Local hemostatic
219
Fibrinogen
--> Local hemostatic
220
Fibrin
--> Local hemostatic
221
Absorbable gelatin sponge
--> Local hemostatic --> absorbed in 4-6 weeks
222
Cellulosic acid
--> Local hemostatic --> clot formation
223
Vitamin K
--> Systemic hemostatic
224
Desmopressin acetate
--> Systemic hemostatic
225
Protamine sulfate
--> Systemic hemostatic
226
Etamsylate
--> Systemic hemostatic
227
Tranexamic acid
--> Systemic hemostatic
228
Carbazochrome
--> Systemic hemostatic
229
Heparin
--> Anticoagulant
230
Dicumarol
--> Anticoagulant --> vit K antagonist
231
Warfarin sodium
--> Anticoagulant --> vit K antagonist
232
Phenprocoumon
--> Anticoagulant --> vit K antagonist
233
Aminocaproic acid
--> Anticoagulant --> fibrinolytic agent
234
Aprotinin
--> Anticoagulant --> fibrinolytic agent
235
Streptokinase
--> Anticoagulant --> fibrinolytic agent
236
Fibrinolysin
--> Anticoagulant --> fibrinolytic agent
237
Acetylsalicylic acid
--> Anticoagulant --> antiplatelet
238
Ticlopidine
--> Anticoagulant --> antiplatelet
239
Dipyridamole
--> Anticoagulant --> antiplatelet
240
Important blood groups in dogs Donors weight
At least 11 1.1, 1.2 and 7 are significant Donors : 20kg BW
241
Important blood groups in cats Donors weight
A (main), B, AB Donors : 4kg BW
242
Important blood groups in bovine
A, B, C
243
Important blood groups in horse
30 blood groups A, C, Q
244
List of blood substitutes
- free hemoglobin - fluorocarbon - oxyglobin
245
Drugs to induce ovarian activity in sow
PG600 : induce estrus FSHp and LHp
246
Drug to advance breeding season
Melatonin implant (ewe, goat, deer) (increase ovulation rate)
247
Drug to reduce interval between calving and estrus
Testosterone
248
Altrenogest
Control the estrus (synchronizing) (gilts, mare) (in food)
249
Progestins
Control the estrus (synchronizing) (heifers, cow, goat) (ear implant)
250
Melengestrol acetate
Control the estrus (synchronizing) (cow, sheep) (oral)
251
Intravaginal progesterone
Control the estrus (synchronizing)
252
CIDR (Controlled Internal Drug Release)
Control the estrus (synchronizing) (sheep, goat, cow)
253
PRID (Progesterone Releasing Intravaginal Device)
Control the estrus (synchronizing) (cow)
254
Gonadorelin
GnRH (Gonadotropin releasing hormone)
255
Fertilerin acetate
GnRH (Gonadotropin releasing hormone) Increase fertility
256
Burserelin
--> GnRH (Gonadotropin releasing hormone) --> Increase fertility --> Induction of ovarian activity in mare
257
HCG then PGF2
Treatment of follicular cyst
258
Treatment of luteum cyst
PGF2
259
Dinoprost
PGF2λ natural
260
Tromethamine
PGF2λ natural
261
Cloprostenol
PGF2λ analog
262
Alfaprostol
PGF2λ analog
263
Fenprostalene
PGF2λ analog
264
Drugs to induce parturition
- cow : PGF2λ, glucocorticoid, estradiol - mare : oxytocin, PGF2λ
265
Post-partum drugs
- oxytocin (for retained placenta) - estrogen (cow : prevent infection) - PGF2λ (for pyometra)
266
Drug to induce superovulation (cow, sow, sheep and goat)
- cow : FSH then PGF2λ - sow : PMSG after weaning - goat/sheep : PGF2λ then gonadotropin
267
Drug to induc lactation
Estradiol, progesterone, dexamethazone, reserpine
268
Tocolytic definition
Inhibit uterine activity
269
Clenbuterole
Tocolytic
270
Atosibane
Tocolytic
271
Drugs to stimulate the gonads in pets
GnRH
272
Drug to induce estrus in bitch
- diethylstilbestrol (then LH and FSH) - PSMG or HCG
273
Drug to induce ovulation in pets
hCG
274
Drug for abortion and evacuation of uterus in pets
PGF2λ
275
Antinidatory medication in pets
Estradiol
276
Mifepristone
Abortigen (pets)
277
Bromocriptine
--> Abortigen (pets) --> Pseudopregnancy (pets)
278
Cabergoline
--> Abortigen (pets) --> Pseudopregnancy (pets)
279
Megestrol acetate
--> Postponement of estrus (contraceptive) (pets) --> Prostatic hypertrophy (pets)
280
Chlormadinone acetate
Postponement of estrus (contraceptive) (pets)
281
Delmadinone
--> Postponement of estrus (contraceptive) (pets) --> Prostatic hypertrophy (pets)
282
Medroxyprogesterone
Postponement of estrus (contraceptive) (pets)
283
Proligestone
Postponement of estrus (contraceptive) (pets)
284
Mibolerone
Postponement of estrus (contraceptive) (pets)
285
Metergoline
Pseudopregnancy (pets)
286
Ergonovine
Uterine inertia (post-partum/abortion hemorrhage) (pets)
287
Drug for cryptorchidism
- HCG - surgery
288
Osateron
Prostatic hypertrophy (pets)
289
Nandrolone
Anabolic drug (for negative nitrogen balance) (pets)
290
Deslorelin
Induction of infertility in male (pets)
291
Goitrogenes
Antithyroid
292
Thionamides
Antithyroid
293
Hydrocortisone
Glucocorticoid
294
Cortisone
Glucocorticoid
295
Prednisone
--> Glucocorticoid --> Hormone antitumor therapy (only palliative)
296
Prednisolone
Glucocorticoid
297
Methylprednisolone
Glucocorticoid
298
Triamcinolone
Glucocorticoid
299
Isoflupredone
Glucocorticoid
300
Flumethazone
Glucocorticoid
301
Dexamethazone
Glucocorticoid
302
betamethazone
Glucocorticoid
303
Desoxycorticosteron acetate
Mineralocorticoid deficiency
304
Fludrocortizon acetate
Mineralocorticoid deficiency
305
Mitotane
--> Hyperadrenocorticism --> Hormone antitumor therapy (only palliative)
306
Trilostane
Hyperadrenocorticism
307
Ketaconazole
Hyperadrenocorticism
308
Treatment of ketosis in cattle
- Insulin - Dexamethasone or isoflupredone acetate - Potassium chloride
309
Sulfonylureas (tolbutamide, talzamide, chlorpropamide, acetohexamide, glimerpiride)
Hypoglycemic agent
310
Metformin
Hypoglycemic agent
311
Acarbose
Hypoglycemic agent
312
Thiazolidinediones
Hypoglycemic agent
313
Glucagon
Hyperglycemic agent
314
Somatostatin
Hyperglycemic agent
315
Diazoxide
- Hyperglycemic agent - for insulinoma
316
Hydrazine sulfate
--> Appetite stimulant
317
Cyproheptadine
--> Appetite stimulant --> Anti-emetic
318
Warm or saline water
--> Emetic
319
Warm sodium chloride
--> Emetic
320
Ipecac syrup
--> Emetic
321
Apomorphine
--> Emetic
322
Ropinirole
--> Emetic (dog)
323
Kaolin Pectin Bismuth salt
--> Anti-emetic (limited action) --> GI protectant/adsorbent
324
Domperidone
--> Anti-emetic --> Stimulator of gastric motility
325
Methscopolamine
--> Anti-emetic --> Anti-ulcer
326
Isopropamide
--> Anti-emetic --> Anti-ulcer
327
Cyclizine
--> Anti-emetic (anti histmainic)
328
Meclizine
--> Anti-emetic (anti histaminic
329
Dyciclomine
--> Anti-emetic (not in cat) --> Anti-diarrheal
330
Triflupromazine
--> Anti-emetic
331
Perphenazine
--> Anti-emetic
332
Meprazine
--> Anti-emetic
333
Trimethobenzamide
--> Anti-emetic
334
Dolasetron
--> Anti-emetic
335
Granisetron
--> Anti-emetic
336
Tropisetron
--> Anti-emetic
337
Maropitant
--> Anti-emetic
338
Aprepitant
--> Anti-emetic
339
Fosfaprepitant
--> Anti-emetic
340
Misoprostol
--> Anti-ulcer
341
Omeprazole
--> Anti-ulcer
342
Pantoprazole
--> Anti-ulcer
343
Lansoprazole
--> Anti-ulcer
344
Sodium bicarbonate
--> Anti-ulcer
345
Aluminium hydroxide
--> Anti-ulcer --> GI protectant/adsorbent
346
Calcium carbonate
--> Anti-ulcer --> GI protectant/adsorbent
347
Sucrose
--> Anti-ulcer
348
Sucralfate
--> Anti-ulcer
349
Bethanechol
--> Stimulator of gastric motility --> Purgative (irritant)
350
Cisapride
--> Stimulator of gastric motility
351
Hyoscine
--> Anti-diarrheal
352
Aminopentamide
--> Anti-diarrheal
353
Mepenzolate
--> Anti-diarrheal
354
Oxyphenonium
--> Anti-diarrheal
355
Benzetimide
--> Anti-diarrheal
356
Pipenozolat
--> Anti-diarrheal
357
Clidinium
--> Anti-diarrheal
358
Camylofine
--> Anti-diarrheal
359
Opium
--> Anti-diarrheal
360
Diphenoxylat
--> Anti-diarrheal
361
Loperamide
--> Anti-diarrheal
362
Drotaverine
--> Anti-diarrheal
363
Sulfasalazine
--> Anti-diarrheal (cats are sensitive)
364
Magnesium trisilicate
--> GI protectant/adsorbent
365
Aluminium trisilicate
--> GI protectant/adsorbent
366
Mineral oil
--> Laxative
367
Methylcellulose
--> Laxative
368
Carboxymethylcelullose
--> Laxative
369
Sorbitol
--> Purgative
370
Lactulose
--> Purgative
371
Sodium sulfate
--> Purgative
372
Sodium phosphate
--> Purgative
373
Vegetable oils
--> Purgative (irritant)
374
Phenolphtalein
--> Purgative (irritant) (only in primate and pigs)
375
Bisacodyl
--> Purgative (irritant)
376
Antraquinonele
--> Purgative (irritant)
377
Danthron
--> Purgative (irritant)
378
Enemas
--> Purgative (neuromuscular)
379
Pepsin
--> Promote digestive functions
380
HCl
--> Promote digestive functions
381
Dehydrocholic acid
--> Promote digestive functions (bile acids) --> Affect the liver : bile salts
382
Chenodiol
--> Promote digestive functions (bile acids)
383
Glycocholate
--> Affect the liver : bile salts
384
Taurocholate
--> Affect the liver : bile salts
385
Ursodeoxycholic acid
--> Affect the liver : bile salts
386
Choline
--> Liver protectant (for synthesis of phospholipids)
387
S-adenosyl-1-methionine
--> Liver protectant
388
Lecithin
--> Liver protectant
389
Treatment for acute pancreatitis ?
- Reduce pancreatic activity : atropine, anticholinergic - Anti-emetic : Maropitant, Ondansetron, Dolasetron - Analgesic : Mepredin, Butorphanol, Buprenorphine
390
Treatment for chronic pancreatitis ?
Pancrelipase : specific pancreatic enzyme
390
Metaproterenol
--> Bronchodilators
390
Indication for bronchodilators
Emphysema, bronchitis, asthma
391
Terbutaline
--> Bronchodilators
391
Albuterol
--> Bronchodilators
391
Theophylline
--> Bronchodilators (only oral admin)
391
Isoetharine
--> Bronchodilators
392
Aminophylline
--> Bronchodilators
393
Oxytriphylline
--> Bronchodilators
394
Cromogylate
--> Bronchodilators (asthma, allergic reaction (rhinitis, conjunctivitis))
395
Zafirlukast
--> Bronchodilators --> For asthma
396
Zileuton
--> Bronchodilators --> For asthma
397
Drug that you can use as antitussive
- narcotic : hydrocodone, codeine, noscapine - non-narcotic : dextromethorphan (for cats), butorphanol - mucokinetic : sodium bicarbonate, sterile and saline water - expectorants : guaifenesin, guaiacol, potassium bromide
398
Chlorpheniramine
--> Decongestants
399
Mechlorethenamine
--> Chemo of neoplastic diseases (alkylating agent)
400
Cyclophosphamide
--> Chemo of neoplastic diseases (alkylating agent)
401
Melphalan
--> Chemo of neoplastic diseases (alkylating agent) --> melanoma
402
Chlorambucil
--> Chemo of neoplastic diseases (alkylating agent) --> leukemia, lymphoma (dog, cat)
403
Busulfan
--> Chemo of neoplastic diseases (alkylating agent) --> lyeloid leukemia
404
Carmustin
--> Chemo of neoplastic diseases (alkylating agent) --> CNS tumors
405
Lomustin
--> Chemo of neoplastic diseases (alkylating agent) --> CNS tumors
406
Dacarbazine
--> Chemo of neoplastic diseases (triazins) --> melanoma, sarcoma, lymphoma (dog)
407
Methotrexate
--> Chemo of neoplastic diseases (antimetabolites) --> carcinoma, lymphoma, rheumatoid polyarthritis
408
Cytrabine
--> Chemo of neoplastic diseases (antimetabolites) --> lymphoreticular tumors, proliferative melanoma
409
Fluorouracil
--> Chemo of neoplastic diseases (antimetabolites) --> GI tumors (dog), cutaneous squamous cell carcinoma (horse, dog) --> CNS toxicity in CATS
410
Mercaptopurine
--> Chemo of neoplastic diseases (antimetabolites) --> leukemia, lymphoreticular tumors
411
Vinblastin sulfate
--> Chemo of neoplastic diseases (toxic agent on cell cycle)
412
Vincristine sulfate
--> Chemo of neoplastic diseases (toxic agent on cell cycle) --> sexually transmissible diseases --> neurotoxicity in CATS --> contreindication : leukopenia, granulocytopenia
413
Taxol
--> Chemo of neoplastic diseases (toxic agent on cell cycle)
414
Mandragora (Teniposide, Etoposide)
--> Chemo of neoplastic diseases (toxic agent on cell cycle)
415
Daunorubicin
--> Chemo of neoplastic diseases (toxic agent on cell cycle)
416
Mitoxantrone
--> Chemo of neoplastic diseases (toxic agent on cell cycle)
417
Doxorubicin
--> Chemo of neoplastic diseases (toxic agent on cell cycle)
418
Bleomycin sulfate
--> Chemo of neoplastic diseases (toxic agent on cell cycle) --> carcinoma (dog, cat)
419
Dactinomycin
--> Chemo of neoplastic diseases (toxic agent on cell cycle) --> Carcinoma, nephroblastoma, testicular tumors, sarcoma
420
L-Asparginase
--> Chemo of neoplastic diseases (toxic agent on cell cycle) -->lymphoma (dog)
421
Cisplatin and Carboplastin
--> Chemo of neoplastic diseases (platinum complexes) --> carcinoma, osteosarcoma, nasal adenocarcinoma
422
Hydroxyurea
--> Hormone antitumor therapy (only palliative)
423
Tigilanol tiglat
--> Hormone antitumor therapy (only palliative) --> subcutaneous mast cell tumors