Pharmacology-HIV Care Flashcards Preview

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Flashcards in Pharmacology-HIV Care Deck (17):
1

Body fluids that do not transmit HIV

Tears, saliva, urine, stool

2

2 highest risk factors for risk of HIV transmission without anti-retroviral therapy

1) Maternal-fetal 30% 2) Receptive anal intercourse 3%. Note that aside from mode of transmission, stage of transmitter is also important (acute HIV is more infectious w/higher viral loads)

3

HIV rash

Maculopapular

4

Differential for atypical lymphocytes on CBC

HIV, EBV, CMV, Lymphoma

5

How long does it take for an ELISA HIV screening test + western blot take to be positive?

6-8 weeks after exposure

6

Common signs and symptoms of HIV infection

Fever, rash, sore throat, lymphadenopathy, thrombocytopenia and leukopenia.

7

Who should be screened for HIV?

ITP, pancytopenia, leukopenia, unexplained nephropathy, shingles in young person, syphilis, acute viral hepatitis (A, B, C), refractory CAP, Tb, transfusion prior to 1985, recurrent giardia/salmonella/shigella, AIDS related cancer, dermatitis, psoriasis

8

What viral antigens are typically assessed on western blot?

p24, gp41, gp120 and gp160. There must be 2 positive bands to have a positive test.

9

1st line for HIV diagnosis

HIV RNA PCR

10

Stages of HIV infection

PHI (primary HIV infection), AHI (asymptomatic HIV infection), SHI (symptomatic HIV infection)

11

Common opportunistic infections

PCP, CMV, toxoplasmosis, Mycobacterium avium-intracellulare

12

Common oncogenic viruses seen in AIDS

Lymphoma, cervical carcinoma, Kaposi’s sarcoma

13

PCP prophylaxis

CD4 < 200 w/TMP-SMX

14

Toxo prophylaxis

CD4 < 100 w/TMP-SMX

15

MAC prophylaxis

CD4 < 50

16

Rule of 3’s for percutaneous virus exposure

HBV 30% (HBIG and vaccine), HCV 3% (no prevention), HIV .3% (ARTs within 2 hours)

17

Increased risk for HIV transmission in occupational exposures

Hollow needle that was deep in tissue, in blood vessels and has visible blood in a patient with PHI, symptomatic HIV or AIDS status.