Pharmacology--specific antidotes Flashcards Preview

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Flashcards in Pharmacology--specific antidotes Deck (20):
1

Acetaminophen

N-acetylcysteine (replenishes glutathione)

2

AChE inhibitors, organophosphates

Atropine > Pralidoxime

3

Amphetamines (basic)

NH4Cl (acidify urine)

4

Antimuscarinic, anticholinergic agents

Physostigmine salicylate, control hyperthermia

5

Benzodiazepines

Flumazenil

6

Beta blockers

Glucagon

7

Carbon monoxide

100% O2, hyperbaric O2

8

Copper, arsenic, gold

Penicillamine

9

Cyanide

Nitrite + thiosulfate, hydroxocobalamin

10

Digitalis (digoxin)

Anti-dig Fab fragments

11

Heparin

protamine sulfate

12

Iron

Deferoxamine, deferasirox

13

Lead

EDTA, dimercaprol, succimer, penicillamine

14

Mercury, arsenic, gold

Dimercaprol (BAL), succimer

15

Methemoglobin

Methylene blue, vitamin C

16

Opioids

Naloxone, naltrexone

17

Salicylates

NaHCO3 (alkalinize urine), dialysis

18

TCAs

NaHCO3 (plasma alkalinization)

19

tPA, streptokinase, urokinase

Aminocaproic acid

20

Warfarin

Vitamin K (delayed effect), fresh frozen plasma (immediate)