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Flashcards in Pharmacology: UTI Deck (130)
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1

How many cases of symptomatic UTI are seen each year?

150 million

2

What is the lifetime risk of having at least 1 UTI among women?

Higher than 50%

3

In very young children, do boys or girls get more UTIs?

Very young boys--> They have a higher frequency of urethral malformations

4

In older kids, who gets more UTIs?

Girls

5

In adults, who gets more UTIs?

Women

6

Why do women get more UTIs?

They have a short urethra, so bacteria has easier access to the urinary tract

7

What category of women get UTIs most commonly?

Sexually active

8

In people over 50, who gets more UTIs?

It is equal between elderly men and elderly women

9

What are the 3 types of UTI with associated % of occurrence?

1. Cystitis (90%)
2. Pyelonephritis (10%)
3. Asymptomatic

10

Which types of UTI are symptomatic?

Cystitis and pyelonephritis

11

What is the description of asymptomatic UTI?

Bacteria in urine, no symptoms

12

Where does cystitis affect?

Bladder and lower UT

13

Where does pyelonephritis affect?

Kidney and upper UT

14

What categorizes sporadic recurrence and what is the % of affect?

Under or equal to 1 UTI in 6 months and under or equal to 2 UTI in a year
75%

15

What categorizes recurrent UTI and what is the % of affect?

Over or equal to 2 UTI in 6 months and over or equal to 3 UTI in a year
25%

16

What are the 2 subcategories under recurrent UTI and describe

1. Relapse: No time between infection and usually with same strain of bacteria
2. Reinfection: Patient is cured from bacteria in urine and there is a period of time with no bacteria...if it comes back, it is usually a different strain

17

What % of UTI are considered complicated?

2%

18

What 4 features are associated with complicated UTI?

1. Structural abnormalities, like a urinary tract obstruction (calculi, catheters, prostatic hypertrophy)
2. Metabolic/hormonal abnormalities (diabetes and pregnancy)
3. Impaired host responses (renal transplants) and AIDS
4. Unusual pathogens (yeast or hospital-acquired infection)

19

What is the consequence of complicating factors?

Longer therapy and a more detailed workup (no guidelines just recommendations.... make sure to treat complication 1st before bacterial infections)

20

What are symptoms of cystitis?

Frequent voiding, burning during and after voiding, suprapubic pain, hematuria and/or cloudy urine

21

What are symptoms of pyelonephritis?

FEVER, flank pain, chills, with or without cystitis symptoms

22

What can cystitis symptoms mimic?

Urethritis from STDs

23

What can be done to differentiate between cystitis and urethritis?

Urinalysis and urine culture

24

What is seen in urinalysis and culture for cystitis?

Pyuria, most have bacteriuria, half have hematuria
-See organisms on culture

25

What is is seen in urinalysis and culture for urethritis?

Pyuria, no bacteruria, no hematuria
-No bacteria on culture

26

What can pyelonephritis be mixed up with?

Renal stones

27

How do you differentiate from pyelonephritis and renal stones?

Similar pain location for both... but pyelonephritis has FEVER

28

What is seen on urine analysis for diagnosis of UTI?

Pyuria with bacteruria

29

What blood tests need to be done with pyelonephritis?

Blood cultures

30

Is CRP a good marker for diagnosis of cystitis and pyelonephritis?

YES