Pharmacy Foundations: Lab values & Drug monitoring Flashcards

1
Q

CBC info

A

includes…
- RBC
- WBC
- Platelets
- Hemoglobin
-Hematocrit

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2
Q

Leukocytosis is…

A

increase in WBC

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3
Q

Polycythemia is…

A

increase in RBC

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4
Q

Thrombocytosis is….

A

increase in platelets

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5
Q

Leukopenia is…

A

decrease in WBC

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6
Q

Anemia is…

A

decrease in RBC

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7
Q

Thrombocytopenia is…

A

decrease in platelets

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8
Q

Calcium reference range

A

8.5-10.5 mg/dL

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9
Q

Chloride reference range

A

95-106 mEq/L

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10
Q

Magnesium reference range

A

1.3-2.1 mEq/L

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11
Q

Phosphate reference range

A

2.3-4.7 mEq/L

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12
Q

Potassium reference range

A

3.5-5 mEq/L

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13
Q

Sodium reference range

A

135-145 mEq/L

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14
Q

Bicarbonate reference range

A

Venous: 24-30 mEq/L
Arterial: 22-26 mEq/L

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15
Q

Blood Urea Nitrogen (BUN) reference range

A

7-20 mg/dL

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16
Q

Serum Creatinine reference range

A

0.6-1.3 mg/dL

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17
Q

Glucose reference range

A

70-110 mg/dL

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18
Q

Anion Gap (AG) reference range

A

5-12 mEq/L

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19
Q

WBC reference range

A

4,000-11,000 cells/mm3

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20
Q

Neutrophil reference range

A

45-73%

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21
Q

Bands reference range

A

3-5%

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22
Q

Eosinophils reference range

A

0-5%

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23
Q

Basophils reference range

A

0-1%

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24
Q

Lymphocytes reference range

A

20-40%

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25
Q

RBC reference range

A

Male: 4.5-5.5 X 10^6 cells

Female: 4.1-4.9 X 10^6 cells

26
Q

Hemoglobin reference range

A

Males: 13.5 -18 g/dL

Female: 12-16 g/dL

27
Q

Hematocrit reference range

A

Males: 38 - 50%

Female: 36 - 46%

28
Q

Mean Corpuscular Volume (MCV) reference range

A

80-100 fL

29
Q

Folic Acid (Folate) reference range

A

5-25 mcg/L

30
Q

Vitamin B12 reference range

A

> 200 pg/mL

31
Q

Reticulocyte Count reference range

A

0.5 - 2.5%

32
Q

Glucose-6-Phosphate Dehydrogenase (G6PD)

A

5-14 units/gram

33
Q

INR reference range (not on warfarin)

A

< 1.2

34
Q

Platelets (PLTs) reference range

A

150k-450k cells/mm3

35
Q

Albumin reference range

A

3.5-5 g/dL

36
Q

Aspartate Aminotransferase (AST) reference range

A

10-40 units/L

37
Q

Alanine Aminotransferase (ALT) reference range

A

10-40 units/L

38
Q

Bilirubin total (Tbili) reference range

A

0.1-1.2 mg/dL

39
Q

Amylase reference range

A

60-180 units/L

40
Q

Lipase reference range

A

5-160 units/L

41
Q

LDL reference range

A

< 100 mg/dL desirable

42
Q

HDL reference range

A

< 40 mg/dL = low (male)
>/= 60 = desirable

43
Q

Non-HLD reference range

A

< 130 mg/dL desirable

44
Q

Triglycerides (TG) reference range

A

< 150 mg/dL

45
Q

C-reactive protein reference range

A

0-0.5 mg/dL, bump indicates inflammation

46
Q

Fasting Plasma Glucose reference range

A

> 126 mg/dL = + diabetes
100-125 mg/dL = + pre diabetes

47
Q

Hemoglobin A1C reference range

A

< 7% = ADA
< 6.5% = AACE

48
Q

Narrow Therapeutic Index (NTI) drugs

A

narrow separation between the subtherapeutic, therapeutic and supratherapetuic drug levels

49
Q

Carbamazepine Therapeutic Drug levels

A

4 - 12 mcg/mL

50
Q

Digoxin Therapeutic Drug levels

A

0.8 - 2 ng/mL (AFib)
0.5 - 0.9 ng/mL (HF)

51
Q

Gentamicin (traditional dosing) Therapeutic Drug levels

A

Peak: 5 - 10 mcg/ mL
Trough: < 2 mcg/mL

52
Q

Lithium Therapeutic Drug levels

A

0.6 - 1.2 mEq/L, up to 1.5 mEq/L for acute systems, done as trough

53
Q

Phenytoin/Fosphenytoin Therapeutic Drug levels

A

10 - 20 mcg / mL: calculate corrected lvl if albumin low

Free Phenytoin: 1 - 2.5 mcg/mL

54
Q

Warfarin INR Therapeutic Drug levels

A

2-3 goal INR most indications, 2.5-3.5 for high res conditions such as mechanical valves

55
Q

Vancomycin Therapeutic Drug levels

A

Trough: 15 - 20 mcg/mL for most serious infections pneumonia, endocarditis, osteomyelitis, meningitis, bacteremia

10 - 15 mcg/mL for other infections

56
Q

Valproic Acid Therapeutic Drug levels

A

50 - 100 mcg/mL, up to 150 mcg/mL for some patients

57
Q

Tobramycin Traditional Dosing Therapeutic Drug levels

A

Peak: 5 - 10 mcg/mL
Trough: < 2mcg/mL

58
Q

Theophylline Therapeutic Drug levels

A

5 - 15 mcg/mL

59
Q

Procainamide Therapeutic Drug levels

A

4 - 10 mcg/mL

60
Q

NAPA (procainamide active metabolite) Therapeutic Drug levels

A

15 - 25 mcg/mL

61
Q

Procainamide + NAPA Therapeutic Drug levels

A

10 - 30 mcg/mL

62
Q
A