Photodermatology Flashcards

1
Q

Inadequate sun exposure in conjunction with a diet deficient in vitamin D can lead to what condition?

A

Osteomalacia (rickets in children)

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2
Q

What are the hazards of UV radiation exposure?

A
Sunburn
Eyes - conjunctivitis, keratitis, cateract
Skin cancer
Photoageing
Photosensitivity - photodermatoses
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3
Q

Out of UVA, UVB and UVC which has the longest wavelength?

A

UVA (then B and C)

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4
Q

The ozone layer blocks which type of UV?

A

UVC

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5
Q

Do windows block UVA or UVB?

A

UVB

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6
Q

Which UV is most biologically potent?

A

UVC (Then B and A)

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7
Q

How many times more potent is UVB compared to UVA?

A

1000 times

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8
Q

Which UV do most sunbeds use?

A

Fluorescent UVA

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9
Q

Which UV is good for psoriasis?

A

UVB

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10
Q

What is PUVA?

A

Light therapy using psoralen and UVA

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11
Q

What can PUVA be used to treat?

A

Psoriasis
Eczema
Vitiligo
Cutaneous T-cell lymphoma

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12
Q

What are the Fitzpatrick skin types?

A
I - Only burns
II - Burns, can tan
III - Tans, can burn
IV - Tans
V - Dark brown skin
VI - Black skin
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13
Q

What’s a mediator for UVA erythema?

A

Oxygen

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14
Q

What’s a mediator for UVB erythema?

A

Prostaglandins

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15
Q

Are melanomas caused by cumulative sun exposure or acute sunburns?

A

Acute sunburns

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16
Q

What is the commonest cancer in caucasians?

A

Basal Cell Carcinoma

17
Q

What type of hypersensitivity is polymorphic light eruption?

A

Type 4

18
Q

Which antibiotics can cause drug-induced photosensitivity?

A

Sulphonamides
Tetracyclines
Fluoroquinolones

19
Q

Which diuretics can cause drug-induced photosensitivity?

A

Thiazides

Frusemide

20
Q

Other than antibiotics and diuretics which drugs can cause drug-induced photosensitivity?

A

Psoralens
NSAIDS
Quinine
Amiodarone

21
Q

What investigation results may be found in porphyria cutanea tarda (PCT)?

A

Abnormal LFTs

Iron overload

22
Q

What conditions have a high prevalence in patients with PCT?

A

Hepatitis C
HIV
Haemochromatosis

23
Q

In PCT what may be found in the urine?

A

High levels of uroporphyrinogen