PHTN Flashcards
1
Q
What is the definition of PH?
A
mean PAP of >20mmHg on RH cath
2
Q
What is the definition of precap PHTN?
A
mPAP >20, mPAWP <15 and PVR <2 wood units
2
Q
Genes associated with PPAH?
A
BMPR2 (70%), EIA2KA- associated with CTEPH, TBR4- also don’t have patellas
2
Q
What did AMBITION show?
A
giving up front combination therapy rather than single therapy. But PD5 inhibitors are given first because of cost in an exam situation
3
Q
What is the definition of LH and post cap PHTN?
A
mPAP >20, mPAWP >15 and PVR >2 wood units
4
Q
When can you give vasodilators in lung related PAH?
A
can be considered if PVR is >5 woods. ie it is disproportionate
