Physio - Aerobic Metabolism

Question 1

How much ATP does glycolysis make from 1 glucose

Answer 1

2 ATP

Question 2

How much ATP does the Krebs cycle make from 1 pyruvate

Answer 2

2 ATP

Question 3

For 1 NADH, how many ATP is made in the electron chain

Answer 3

~3 ATP

Question 4

The total ATP production via aerobic breakdown of glucose is

Answer 4

~32 ATP
2 ATP (glycolysis)
2x 1 ATP (Kreb cycle)
10 NADH = ~24 ATP (electron transport chain)
2 FADH₂ = ~4 ATP (electron transport chain)
2 + 2 + 24 + 4 = ~32

Question 5

What are the steps of aerobic metabolism

Answer 5

1. Anaerobic glycolysis
2. Acetyl CoA production
3. Krebs / citric acid cycle
4. Electron transport chain

Question 6

Name 3 sources of Acetyl CoA

Answer 6

Glucose
Fatty acids
Amino acids

Question 7

What are the 3 metabolic reactions to form Acetyl CoA

Answer 7

Glycolysis of glucose
Oxidation of fatty acids
Amino acid deamination

Question 8

Where does glycolysis occur

Answer 8

The cytoplasm

Question 9

Where does glycolysis the Kreb cycle occur

Answer 9

In the mitochondria, in its matrix

Question 10

For 1 FADH₂, how many ATP is made in the electron chain

Answer 10

~2 ATP

Question 11

What are the key net compounds produced in glycolysis

Answer 11

2 ATP
2 NADH + (2 H⁺)
2 Pyruvate + (2 H₂O)

Question 12

What are the key net compounds produced in the Kreb cycle

Answer 12

2 ATP
6 NADH
2 FADH₂
(2 CO₂)

Question 13

What are the key net compounds produced in glycolysis and the Kreb cycle

Answer 13

4 ATP
~8 NADH
2 FADH₂

Question 14

Where does the electron transport chain occur

Answer 14

On the inner mitochondrial membrane

Question 15

What is the first step of the electron transport chain

Answer 15

NADH and FADH₂ transfer there electrons
NADH = NAD⁺ + H⁺ + 2e⁻
FADH₂ = FADH⁻ + 2H⁺ + 2e⁻

Question 16

What is the second step of the electron transport chain

Answer 16

Electrons are moved; some are used to pump H⁺ into the outer compartment

Question 17

What is the third step of the electron transport chain

Answer 17

H⁺ diffuse through ATP synthase into the inner compartment, matrix, forming water
2H⁺ + 2e⁻ + ½O₂ = H₂O

Question 18

What is the Fourth step of the electron transport chain

Answer 18

A carrier protein swaps ATP with ADP; another carrier protein moves a phosphate into the inner compartment.
The ADP and phosphate are then combined in the ATP synthase to form ATP

Question 19

What must occur for pyruvate to enter the Kreb cycle

Answer 19

Oxidation to become Acetyl CoA
Pyruvate –oxidation–> Acetyl CoA NADH + H⁺