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Flashcards in Physiological processes of Pain Deck (17):
1

Pharmacokinetics is concerned with the processes of ...

absorption, distribution, metabolism, elimination of drugs

2

What is Neuropathic pain

Pain relating to damage to the nerve fibres themselves

3

What is Nociceptor

The ends of specialised nerve fibres that detect 'noxious' or tissue-damaging stimuli

4

What is Descending pain modulation

Pain is mediated by neurotransmitters such as endorphins, serotonin and nor-adrenaline that are released in the dorsal horn.

5

Which of the following is NOT true about opioid analgesics?

Select one or more:
a. Opioid receptors are widely distributed in the brain and spinal cord
b. Morphine is more potent than diamorphine
c. Opioids act as agonists at opioid receptors
d. Side effects of opioid analgesics include constipation, respiratory depression, and nausea and vomiting

Morphine is more potent than diamorphine

6

Substance P, Beta-endorphins, dopamine, epinepherine, and nor-epinepherine are examples of:

Select one or more:
a. Sandwich fillings
b. Vasodilators
c. Prostaglandins
d. Neurotransmitters

Neurotransmitters

7

The conversion of noxious stimuli to nerve impulses by nociceptors is called....

Nociception

8

The movement of nerve impulses along defined pathways to reach the brain is called...

Transmission

9

An increase or decrease in our perception of pain is known as...

Modulation

10

The conscious experience of pain that arises through stimulation of higher brain centres is called

Perception

11

According to the WHO analgesic ladder all of the following drugs are 'simple pain killers' EXCEPT:

Select one or more:
a. Gabapentin
b. Aspirin
c. Ibuprofen
d. Paracetamol

Gabapentin

This is an adjuvant drug for neuropathic pain

12

Which of the following is true about the chemoreceptor trigger zone?

Select one or more:
a. a portion of the central nervous system associated with vision, hearing, motor control, sleep/wake, arousal (alertness), and temperature regulation.
b. physical representation of the human body, located within the brain
c. is an area of the medulla oblongata that receives inputs from blood-borne drugs or hormones, and communicates with other structures in the vomiting center to initiate vomiting.
d. One of the two parts of the cerebral cortex linked to speech

an area of the medulla oblongata that receives inputs from blood-borne drugs or hormones, and communicates with other structures in the vomiting centre to initiate vomiting

13

Which of the following is TRUE about prostaglandin

a. Prostaglandins increase the threshold at which the pain receptors fire
b. Prostaglandin is the active ingredient in ibuprofen gel
c. Prostaglandins regulate the length of the nerve impulse
d. Prostaglandins have hormone-like actions that increase pain by sensitising receptors

Prostaglandins have hormone-like actions that increase pain by sensitising receptors

14

Neuropathic pain is caused by

Select one or more:
a. Damage to nerve fibres themselves
b. Taking too many pathophysiology quizzes
c. High blood pressure
d. Pain causing signals like high temperature or intense pressure

Damage to nerve fibres themselves

15

Drugs are usually metabolised in the...

a. Liver

16

Salbutamol (Ventolin) is an example of what category of drugs?

Select one or more:
a. Anti-muscarinic bronchodilator
b. Alpha-adrenergic agonist bronchodilator
c. Beta-2 Agonist bronchodilator
d. Parasympathetic bronchodilators

Beta-2 Agonist bronchodilator

17

In pharmacology, an agonist is a substance that fully activates the receptor it binds to. What is an example of an 'agonist' drug?
Select one or more:
a. Morphine (opiate)
b. Amlodipine (calcium channel blocker)
c. Naloxone
d. Propranolol (beta blocker)

Morphine (opiate)

morphine is an opiate agonist