Physiology Flashcards

1
Q

What is a neurohormone

A

When a neurone releases a hormone into the blood

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2
Q

What is a paracrine hormone

A

A hormone with local effect to its release

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3
Q

Name of hormone before it becomes functional

A

Prohormone

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4
Q

Name of cleaved ineffective hormone associated with insulin

A

C-peptide

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5
Q

What is a tropic hormone

A

A hormone which regulates release of another hormone

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6
Q

What does trophic mean

A

Hormone has an effect on growth

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7
Q

1 order disorder

A

Defect in hormone secreting cell

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8
Q

2nd order secretion

A

Little or too much tropic hormone from pituitary

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9
Q

3rd order

A

related to hypothalamic defect

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10
Q

Endocrine part of pancreases name

A

islets of langerhans

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11
Q

What cells secrete glucagon

A

alpha

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12
Q

What cells secrete insulin

A

Beta

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13
Q

What cells secrete somatostatin

A

delta

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14
Q

insulin stimulates what receptors in adipose and skeletal muscle cells

A

Glut-4

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15
Q

Effect of increased glucose on insulin and glucagon

A

Increases insulin

Decreases glucagon

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16
Q

Effect of amino acids on insulin and glucagon

A

Increases both

17
Q

What 2 things are needed for growth hormone to be effective

A

IGF-1

Thyroid hormone

18
Q

What stimulates release of IGF-1

A

Growth Hormone

19
Q

What organ releases IGF-1

A

Liver

20
Q

Effects of growth hormone

A

1- Increases blood glucose
2- inhibits insulin receptors on muscle and adipose
3- promotes lipolysis
4- increases amino acid uptake

21
Q

The 2 basic functions of thyroid hormone

A

Growth

Metabolism (catabolic of fat and protein)

22
Q

What condition produces antibodies which mimic TSH

A

Graves Disease

23
Q

Another word for adrenaline

A

Epinephrine

24
Q

What part of adrenal gland is neuroendocrine

A

Adrenal medulla

25
Q

What part of adrenal gland is classic endocrine

A

Adrenal cortex

26
Q

What is produced in Adrenal medulla

A

epinephrine

norepinephrine

Dopamine

27
Q

What is produced in Adrenal Cortex

A

Mineralocorticoids-Aldosterone (Na and K balance)

Glucocorticoids-Cortisol (maintain glucose levels in plasma)

Sex Steroids- only very small portion, most made in gonads

28
Q

What hormones increase Ca conc in plasma

A

Parathyroid hormone

Calcitriol

29
Q

What hormone decreases Ca conc in plasma

A

Calcitonin

30
Q

How does PTH (parathyroid hormone) act

A

Stimulates osteoclasts to reabsorb bone

Inhibits osteoblasts from depositing bone

Increases secretion of phosphate in urine (Phosphate + Calcium needed for bone)

Increases reabsorption of Ca in kidneys

Stimulates kidney to produce calcitriol

31
Q

How does calcitriol act

A

Increases Ca absorption in the intestine

Increases Ca absorption in kidney

Increases Phosphate absorption in kidney

Mobilises Ca stores in bone

32
Q

What 2 molecules does calcitriol cause the reabsorption of

A

Calcium

Phosphate

33
Q

What hormones Stimulate release of Ca from bone

A

Parathyroid Hormone (PTH)

Calcitriol

Cortisol

34
Q

What does ACTH stimulate the release of

A

cortisol