type 2 diabetes treatment Flashcards by Hamish Anderson | Brainscape

Q

Action of metformin

A

Increase insulin sensitivity

decrease gluconeogenesis

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Q

Complications of metformin

A

Lactic acidosis

GI upset

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Q

suffix of sulfonylurea

A

ide

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Q

Complications of sulfonylurea

A

Cardiovascular!

hypoglycaemia

weight gain

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Q

How do sulfonylureas act

A

Increase insulin secretion

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Q

Suffix of SGLT-2 inhibiter

A

gliflozin

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Q

Action of SGLT-2 inhibiter

A

Inhibits glucose reabsorbsion in kidney

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Q

Main complications of SGLT-2 inhibitors

A

UTI is main

Weight loss

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Q

suffix of GLP-1 mimetic

A

tide

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Q

Action of GLP-1 mimetic

A

act as a incretin and cause increased insulin release and increased glucagon secretion

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Q

complications of GLP-1 memetics

A

GI upset

weight loss

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Q

suffix of DDP-4 inhibitor

A

gliptin

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Q

Function of DDP-4 inhibitor

A

Inhibits enzyme which breaks down incretins

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Q

Side effects of DDP-4 inhibitors

A

GI upset

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Q

Action of pioglitazone

A

Increases insulin sensitivity

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Q

Side effect of pioglitazone

A

Bladder cancer

Fluid retention

weight gain