Piri Lecture 1 Flashcards

(32 cards)

1
Q

what are the steps of the auditory system

A

-sound waves transport energy which travels through the outer ear via the auditory canal and through the tympanic membrane (middle ear)
-they trigger hair cells on the cochlea’s organ of corti (inner ear) releasing neurotransmitters onto spiral ganglion cells
-spiral ganglion cells send information to the cochlear nuclei, superior olive, inferior colliculus, then to the thalamus, then finally the primary auditory complex

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2
Q

infrasound

A

less than 20Hz (frequency lower than what humans can perceive)

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3
Q

ultrasound

A

more than 20kHz (frequency higher than what humans can perceive)

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4
Q

auditory canal

A

-“closed tuber resonator” (enhances sounds bw 2kHz and 5kHz
–part of the outer ear
-outer window exerts 20x pressure onto the tympanic membrane causing the amplification of the sound waves

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5
Q

parts of the middle ear

A

-tympanic membrane
-ossicles (malleus, incus, stapes)
-eustachian tube

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6
Q

what does the eustachian tube do

A
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7
Q

attentuation reflex

A

contraction of muscles which are supposed to adjust fluid and amplify sound waves in the oval window/cochlea, protects against harmfully loud sounds

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8
Q

perilymph

A

fills scala vestibuli and scala typani

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9
Q

endolymph

A

fills scala media

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10
Q

endolymph is _________ positive than perilymph which is important for the creation of _____________

A

more, endocochlear potential

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11
Q

high concentration of sodium, low concentration of potassium

A

perilymph, scala vestibuli, scala tympani

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12
Q

high concentration of potassium, low concentration of sodium

A

endolymph, scala media, due to the stria vascularis potassium pump maintaining this concentration

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13
Q

if you unwind the cochlea, it is wider at the ______ and narrower at the _________

A

base, apex

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14
Q

helicotrema

A

hole in the apex of the cochlea which connects the scala vestibuli and scali tympani (perilymphs)

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15
Q

the basilar membrane is wider at the ________ and narrower at the __________

A

apex, base

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16
Q

t/f: the basilar membrane is most stiff at the base and least stiff at the apex

17
Q

where do lower sound frequency waves travel to in the basilar membrane

18
Q

where do higher sound frequency waves travel to in the basilar membrane

A

the base (not as far)

19
Q

what is the organ of corti

A

the sensory area of the cochlea

20
Q

what do inner hair cells primarily synapse with

A

sensory afferents

21
Q

what do outer hair cells primarily synapse with

A

sensory efferents

22
Q

how are hair cells depolarized

A

-when stereocillia lean towards the largest stereocillium, tip links joining each stereocillium potassium channels loosen and potassium mechanoreceptor ion channels open
-stereocillia are in the endolymph (scala media), so high external potassium causes an influx into hair cells (depolarization)
-depolarization then causes the opening of voltage gated calcium channels downstream resulting in NT release

23
Q

which kind of hair cells detect most sound information

A

inner hair cells

24
Q

phase locking

A

the regular/pattern following consistent firing of hair cells for a given sound frequency, lost at higher frequencies

25
lesion in the cochlear nucleus
ipsilateral loss of hearing
26
lesion in the superior olive
partial loss of hearing
26
lateral superior olive
encodes sound location through intensity differences, -opposite side LSO is inhibited
27
conductive hearing loss
issue w conduction of hearing loss in the outer or middle ear,
28
sensorineural hearing loss
issue in cochlea/inner ear or pathway from cochlea to the brain
29
left belt hemisphere of cortex
plays important role in speech processing
30
right belt hemisphere of cortex
plays important role in tonal stimuli and music
31
intraural time difference
-mechanism used to understand the location of sounds with frequencies under 2kHz -accomplished via MSO neuron which fires most strongly when there are coincident synapses from the left and right ear sound waves -if the sound is closer to the left ear, coincidence will occur farther away from left than right (sound wave via left ear will have more time to travel to MSO)