Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Endocrine Physiology > Pituitary, Thyroid, Parathyroid > Flashcards

Pituitary, Thyroid, Parathyroid Flashcards

(68 cards)

Start Studying
1
Q

GH effect on body (4)?

A

Increased Protein Synthesis
Increased Mineral Density/Bone Gowth
Decreased Carb metabolism
Increased Fat metabolism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

GH effect on blood glucose?

A

Raises (Diabetogenic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

IGF-1 released from where?

A

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What would you expect to happen to GH release after Insulin administration?

A

Increased release to raise blood sugar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What would you expect to happen to GH after glucose administration?

A

Decreased GH release (SST release?)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What happens in GH deficient patients with Insulin test?

A

GH stays low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What happens in GH hypersecretion patients with glucose administration?

A

GH stays high

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

D2 receptor acts via what to lower prolactin and GH?

A

Gi –> Decreased cAMP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

3 direct actions of TSH?

A

T3 and T4 secretion
Increase thyroid peroxidase action
Increase Na/I pump

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Actions of Thyroid Peroxidase (2)?

A

Organification I- –> I2

Conjugation of MIT/DIT –> T3 and T4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Three carriers for Thyroid hormone?

A

TBG
Transthyretin
Albumin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which thyroid carrier holds more T4 than T3?

A

Transthyretin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which thyroid carrier holds more T3 than T4?

A

Albumin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where is deiodinase I found?

A

Liver Kidneys

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where is deiodinase II found?

A

Brain, Muscle, Pituitary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where is deiodinase III found?

A

Brain Skin Placenta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which deiodinases deactivate?

A

1 and 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which deiodinases activate T4–>T3?

A

1 and 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Coarse face, myxedema, cold intolerance, wt gain?

A

HYPOthyroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Lid Lag, Exophthalmos, osteoporosis, moist skin, wt loss?

A

HYPERthyroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

MCC of hypothyroid?

A

Hashimoto

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

MCC of hyperthyroid?

A

Graves’

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Anti-Peroxidase Ab and Hurthle Cells diagnostic for?

A

Hashimoto

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Hashimoto has painful or painless thyroiditis?

A

Painless

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What happen to thyroid usually after pregnancy?
Self-limiting Hyperthyroidism (Silent thyroiditis)
26
Which thyroiditis is usually painful?
DeQuervain Thyroiditis
27
Which thyroiditis usually follows a URTI and has multinucleate giant cells?
DeQuervian Thyroiditis
28
Reidel's Thyroiditis pathogenesis?
Fibroblasts create "wooden thyroid"
29
Graves' disease pathogenesis?
TR stimulating Abs
30
Graves' disease triad?
Hyperthyroid Ophthalmopathy Dermatopathy (pretibial myxedema)
31
Cabbage, brussel sprouts, turnips, and califlower inhibit what?
Iodine uptake
32
4 types of thyroid carcinoma?
Papillary Follicular Medullary Anaplastic
33
MCC of thyroid carcinoma?
Papillary
34
Which thyroid carcinoma looks like an adenoma?
Follicular
35
Orphan Annie eyes and psammoma bodies in which carcinoma?
Papillary
36
Which thyroid carcinoma is of the C Cells?
Medullary
37
Two pathological findings in Medullary thyroid carcinoma?
Nesting pattern | Amyloidosis
38
Anaplastic thyroid carcinoma looks like what other cancer?
Lymphoma
39
Moan, Stone, Bone, Groan?
Hyperparathyroid
40
Primary hyperparathyroid MCC?
Parathyroid adenoma
41
Secondary hyperparathyroid MCC?
Chronic Renal Failure with low Ca
42
Pseudohyperparathyroidism
Small Cell Lung Cancer secretes PTH-like hormone
43
Lab differences between primary and secondary hyperparathyroid?
``` Primary = high Ca Secondary = low Ca ```
44
Parathyroid direct actions (4)?
Increased M-CSF and RANK-L Increased Kidney Ca reabsorption in DCT Decreased PO4 reabsorption in PCT Increased 1,25OH-VitD synthesis via 1-a-hydroxylase
45
1,25 Vit D effect on Ca?
Increased Intestinal Ca absorption | Increased Intestinal PO4 absorption
46
Negative regulators of PTH?
1,25 Vit D High Ca VERY Low Mg
47
Stimulation of PTH?
Low Ca | Low Mg
48
Chvostek's sign and Trousseau's sign are indicative of what?
Hypo-calcemia
49
4 causes of HYPOparathyroid in descending order?
- Accidental surgical removal of Parathyroid - DiGeorges 22q11 - Idiopathic - Familial
50
Normal relationship between GH and IGF1? What does low IGF1 indicate?
GH stimulates IGF1 release | Low IGF-1 Indicates Low GH (or possibly malnutrition)
51
Normal sequence of hormone loss in hypopiuitarism?
GH --> FSH/LH --> TRH --> ACTH
52
What disease's are possible with anti-TSH-R or anti-thyroglobulin Autoantibodies?
Hashimoto's | Graves
53
Parathyroid Hormone Direct Actions (3)?
Mobilize Ca from Bones (Osteoblast signal to Osteoclast) Increase Kidney Ca reabsorption Increased Vit D (Increasing Intestinal Ca absorption)
54
What hormone has the greatest direct effect on epiphyseal plate growth?
IGF1
55
Direct function of Thyroid Peroxidase?
MIT/DIT --> T3/T4
56
TSI stands for what?
Thyroid Stimulating Igs
57
What disease would you expect to have elevated TSI?
Grave's Thyroiditis
58
What cells in the parathyroid secrete PTH?
Chief Cells
59
Darker cells in parathyroid gland? Lighter?
``` Darker = Chief Lighter = Oxyphils ```
60
Infundibulum of the pit is derived from what germ layer?
Neural ectoderm (Neurohypophysis)
61
Acidophiles in the ant pit secrete what?
GH | Prolactin
62
Pituicytes are found in what area of the pituitary?
Post. Pituitary (The nucleated cells there)
63
Innervation of pineal gland?
Post-ganglionics from the superior cervical ganglion
64
Melatonin effects?
Suppress gonadotropin | Retards gonadal growth
65
Thyroid endodermal pouch derivatives?
I and II
66
Parathyroid pouch derivatives?
III and IV
67
Parafollicular cell pouch derivatives?
IV
68
What origin cell type gives rise to parafollicular cells?
NCC

Endocrine Physiology (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions