PNS

Question 1

General side effects of PNS agonists

Answer 1

§ salivation
§ sweating
§ bronchoconstriction
§ bradycardia
§ diarrhea
§ bronchial mucus secretion

Question 2

Name PNS agonists

Answer 2

Neostigmine, edrophonium, donepezil, pilocarpine, malathion, rivastigmine

Question 3

Method of action of edrophonium

Answer 3

Reversible acetylcholine esterase inhibitor

Question 5

Method of action of malathion

Answer 5

Irreversible acetylcholine esterase inhibitor

Question 6

Method of action of donepezil

Answer 6

Reversible acetylcholine esterase inhibitor in brain

Question 7

Method of action of rivastigmine

Answer 7

Acetylcholine esterase inhibitor

Question 8

Method of action of pilocarpine

Answer 8

Non-selective muscarinic receptor agonist

Question 9

Use of neostigmine

Answer 9

§ Muscle weakness
§ treatment of myasthenia gravis
§ post-surgical ileus

Question 10

Use of edrophonium

Answer 10

§ muscle weakness
§ diagnosis of myasthenia gravis
§ post-surgical ileus

Question 11

Use of pilocarpine

Answer 11

§ Dry mouth

§ glaucoma

Question 12

Use of malathion

Answer 12

Head and body lice

Question 13

Use of donepezil

Answer 13

Alzheimer’s

Question 14

Use of rivastigmine

Answer 14

Alzheimer’s and mild dementia

Question 15

Unusual side effect of pilocarpine

Answer 15

Vasodilation

Question 16

Administration of neostigmine

Answer 16

IV

Question 17

Admin of edrophonium

Answer 17

Oral, IV

Question 18

Admin of pilocarpine

Answer 18

Oral, eye drops

Question 19

Admin of malathion

Answer 19

Oral, topical, inhalation

Question 20

Admin of donepezil

Answer 20

Oral

Question 21

Admin of rivastigmine

Answer 21

Oral, transdermal patch

Question 22

General side effects of PNS antagonists

Answer 22

Dry mouth

Question 23

Name PNS antagonists

Answer 23

§ atropine
§ ipratropium bromide
§ hyoscine

Question 24

Method of action of PNS antagonists

Answer 24

Anticholinergic, meaning they competitively bind to muscarinic receptors blocking acetylcholine

Question 25

Use of atropine

Answer 25

§ bradycardia
§ organophosphate poisoning (insecticides)
§ to inhibit mucus and salivary glands
§ bronchoconstriction

Question 26

Use of ipratropium bromide

Answer 26

§ COPD | § diarrhea

Question 27

Method of action of neostigmine

Answer 27

Reversible acetylcholine esterase inhibitor

Question 28

Use of hyoscine

Answer 28

§ IBS | § diarrhea

Question 29

Atropine side effects

Answer 29

``` Dry mouth Tachycardia Constipation Blurred vision Urine retention ```

Question 30

Ipratropium Bromide side effects

Answer 30

Dry mouth | Sedation

Question 31

Hyoscine side effects

Answer 31

``` Dry mouth Tachycardia Constipation Blurred vision Urine retention ```

Question 32

Atropine admin

Answer 32

IV | Topical

Question 33

Hyoscine admin

Answer 33

``` Oral Subcutaneous Opthalmic IV Transdermal patch ```

Question 34

Ipratropium bromide admin

Answer 34

Inhalation