Poisons Flashcards

(34 cards)

1
Q

Treatment for acetaminophen ingestion <4hrs

A

Activated charcoal

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2
Q

Tx for acetaminophen ingestion > 4 hrs

A

Acetaminophen level and plot on nomogram

If more than 140 mg/kg ingested then give N acetylcistine even without getting level

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3
Q

When can lfts become elevated after acetaminophen ingestion

A

3-4 days after

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4
Q

How do you manage salicylate ingestion

A

Activated charcoal

And sodium bicarbonate to alkalinize the urine

The acidosis is caused by a respiratory alkalosis

Address hypokalemia and consider glucose

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5
Q

How do you calculate anion gap

A

Sodium - (chloride + bicarb)

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6
Q

What level of ethanol do you worry for coma, respiratory depression and death

A

Greater than 0.4 g/dl

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7
Q

What do you monitor for in a pt with ethanol toxicity

A

Hypoglycemia and electrolyte imbalance

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8
Q

How does methanol toxicity present

A

Abdominal pain, vomiting, inebriation, severe metabolic acidosis, increased anion gap, cns depression

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9
Q

Where can you find methanol

A

Windshield washer fluid, cooking fuel, perfumes

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10
Q

Tx for methanol toxicity

A

Ethanol

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11
Q

Presentation of organophosphate

A
Cholinergic effect (parasympathetic)
Dumbbels
Diarrhea
Urination
Miosis
Beonchospasm
Bradycardia
Emesis
Lacrimation
Salivation
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12
Q

What are the two categories of cholinergic effects and how are they treated

A

Muscarinic - salivation, lacrimation, diarrhea, wheezing, bradycardia. Tx atropine

Nicotinic- weakness, paralysis, fasiculations. Tx with pralidoxime

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13
Q

What are anticholinergic effects (sympathetic system) and what’s a MED example

A

Blind as a bat, red as a beet, hot as a hare, dry as a bone, mad as a hatter and the heart runs alone

TCA, Benadryl

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14
Q

Findings in Ekg for tca intoxication

A

Widened qrs complex

Tx this with sodium bicarb boluses until qrs less than 100 msec

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15
Q

How does ingestion with hydrocarbons present

A

N/V, cough or wheezing

Lab findings will show hypoxemia

XRAY will show diffuse bilateral infiltrates

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16
Q

Tx for carbon monoxide poisoning

A

High flow oxygen even with normal pulse ox

17
Q

Buzzword for cyanide poisoning

A

Smell of almonds

18
Q

3 phases of ethylene glycol

A

1: náusea, vomiting, tachy, hypertension, metabolic acidosis and calcium oxalate crystals in urine
2: coma and cardiorrespiratorio failure due to acidosis and hypocalcemia
3: 1-3 days renal failure due to tubular necrosis with pt needing dialysis

19
Q

What poisoning gives you garlic smell breath

A

Organophosphate

20
Q

What gives you wintergreen odor on breath

A

Salicylate ingestion

21
Q

Radio opaque materials on X-ray

A

Chips

Chloral hydrate 
Heavy metals
Iron 
Phenothiazines 
Slow release enteric coated materials
22
Q

What parts of body do alkali substances affect

23
Q

What parts of body do acidic substances affect

A

Esophagus and stomach

24
Q

Symptoms for lead level between 10-20 mcg/dl

A

Mild cognitive delay

25
Intervention for lead levels between 10-20 mcg/dl
Education, environmental control and monitoring
26
Symptoms for lead level greater than 70 mcg/dl
Severe toxicity, headaches, encephalopathy, lead lines on gingival and or anemia
27
Tx for lead levels greater than 70
Chelation
28
What are ways that kids are exposed to lead
Eat paint chips or exposed to household dust or soil
29
Phase 1 of iron ingestion
Within 6 hrs vomiting (often bloody), diarrhea, abdominal pain
30
Phase 2 iron ingestion
Quiescent and improvement over next 6-24 hrs
31
Phase 3 iron ingestion
Multi system, shock and organ failure Metabolic acidosis, coagulopathy, cardiovascular collapse
32
Phase 4 iron ingestion
recovery. GI obstruction can be caused due to scarring and structures
33
Lab findings in iron ingestion
Serum iron > 350, WBC > 15k, glucose > 150
34
Indications for chelation with deferoxamine for iron ingestion
Severe symptoms along with anion gap acidosis, iron > 500, significant number of pills visible on abdominal XRAY