Polycystic Ovarian Syndrome Flashcards
(17 cards)
Which criteria is used in PCOS
Rotterdam Criteria
Describe the Rotterdam criteria
2 out of the 3 must be present
- Polycystic ovaries
- Oligo-Ovulation or an ovulation
- Clinical and/or biochemical signs of hyperandrogenism
Symptoms of PCOS
Hirsutism Amenorrhoea Oligomenorrhoea Increased weight Decreased fertility Miscarriage Acne/oily skin
What is Hirsutism
Excessive hair growth
Main 1st line management for PCOS
Weight loss
Other Rx for PCOS
Metformin Clomifene OCP with antiandrogen effect Mirena Eflornithine
Surgical Rx for PCOS
Ovarian drilling
What is the purpose of Eflornithine Rx
to reduce facial hair
What is the action of clomifence
Induce ovulaiton
What may be required for fertility complications in PCOS
IVF
Long term complications of PCOS
Gestational DM Type II DM CVS Infertility Endometrial cancer Endometrial hyperplasia
Imaging Ix for PCOS
Transvaginal USS
Blood Ix for PCOS
FBC
U&E’s
TFTs
Androgen levels
FSH
Prolatcin
Risk factors for PCOS
FH
Premature menarche
Low birth weight
Fetal ansogen exposure
What is PCOS a leading cause of
Infertility
What are the main treatment goals of PCOS
Reduce hyperadrogenism
Induce fertility
Is PCOS associated with insulin resistance
Yes
Unclear why