Flashcards in Population Genetics Deck (15):
What does polymorphic mean?
allelic variants present in more than one percent of the population
How do consanguineous matings change the gene pool?
increase in homozygote frequency
What does linkage disequilibrium mean?
non-random association of alleles at two or more loci
In X-linked recessive diseases, what is the allele frequency?
fraction of the males who are affected
CFTR heterozygotes carry a protection against?
Sickle cell anemia carry a protection against?
beta-thalassemia carry a protection against?
Hemochromatosis carry a protection against?
What is assortative mating?
selection of partners based on specific genetic traits
Old Order Amish of Lancaster county are susceptible to?
ellis van Creveld disease
Ashkenazi jews are susceptible to?
French Canadians are susceptible to?
What does linkage mean?
meiotic recombination between two markers is somewhat unlikely
What is linkage disequilibrium?
recombination of two markers is found more frequently than predicted