Postmortem Changes Flashcards
What are the immediate changes?
Happens within few mins
Loss of brain func (earliest), then circulation, and respiration
What are the early changes?
Occurs within hours to days
Skin, eye changes
Algor mortis (cooling)
Livor mortis (staining)
Rigor mortis (rigidity)
What are the late changes?
Occurs within days to weeks
Putrefaction
Adipocere
Mummification
What are the skin changes?
Pallor
Loss of elasticity
What are the changes in muscle?
Primary flaccidity of muscle
Loss of muscle tone
Drooping of jaw
Relaxation of sphincter
What are the eye changes?
Few mins - railroad appearance of retinal vessels
3-6 hrs - tache noire sclerotica (triangle shaped opacities) & dust deposition (reddish brown) in sclera
1-6 hrs - corneal opacity
Flaccidity of eye ball
Dilation of pupil
Loss of corneal & pupillary reflexes
When does algor mortis occur?
15 minutes after death
Instrument used and sites that can be used measure temperature
Instrument - thanotometer
Sites - rectal, sub-hepatic, intra-tracheal, intranasal, middle ear cavity
Formula to calculate PM interval (hrs)
PM interval (hrs) = (normal body temperature - rectal temperature)/rate of temperature fall (hrs)
What is the usual rate of fall in temperature?
0.4-0.7 per hour
Factors affecting algor mortis
Location of the body
Naked/clothed
Weather/season
Environment (water/underground)
PM caloricity
Body remains warm for 1-2 hours, seen when body core temperature increases at time of death
Eg. Heat stroke, pontine hemorrhage, strychine poisoning, tetanus, septicemia and cholera
MLI of algor mortis
Time since death
What is livor mortis?
Bluish/purplish discoloration of skin after death due to settling down of blood in the toneless capillaries in the dependent portions of the body.
When does PM lividity appear?
Begins 1-2 hours after death (patches)
Completes by 4-6 hours
When does PM lividity get fixed?
Hemolysis & diffusion of pigments to skin by 6-8 hours
What is contact pallor?
Areas of tight contact -> compression of vessels leading to no PM staining
E.g tight clothing, at pressures points
Conditions where PM lividity will not develop
Tossing of body in flowing water
Severe anemia
Hemorrhagic/hypovolemic shock
Difference between PM lividity and bruise
PM - seen in the skin, on dependent parts, no swelling, uniform in color and on incision slight oozing blood seen which can be washed away
Bruise - seen under the skin anywhere, swelling maybe present, different colors and it extravasated blood
MLI for PM lividity
Sign of death
Time since death
Position of the body at the time of death
Whether body was moved
Cause of death
What is rigor mortis?
Stiffening of the body after death
3 phases - primary flaccidity, rigor mortis, secondary flaccidity
What is the pathophysiology of rigor mortis?
After death, ATP depletes
- rigor begins when ATP decreases to 85% of its storage
- rigor maximum when ATP decreases to 15% of its storage
Then actin myosin filaments are bound by dehydrated , stiff, gel-like mass causing the muscles to become rigid
Explain the rule of 12
Rigor mortis begins to appear 1-2 hours after death. Gets well established in 9-12 hours. Maintained in that state for 12 hours and then after another 12 hours it disappears.