PPT 4 Flashcards
(11 cards)
3 main goals of adaptive immunity
recognize nonself cells/invaders
- mount response
- remember the invader
Types of Specific Immunity
HUMORAL: antibody mediated, based on antibody activity
CELLULAR: cell-mediated, based on action of specific kinds of T lymphocytes
Antigen
any substance that elicits an immune response (immunogen)
protein, polysaccharide, NA, or lipid
(multiple epitopes/region of recognition)
Active Immunity
person developing their own immune response to a microbe
Passive Immunity
receiving performed immunity made by another person
MHC
Major Histocompatibility Complex
-collection of genes (HLA) human leukocyte antigen complex
Class I molecules
organ transplantation
-nucleated cells
Class II molecules
antigen presenting cells
Tcell comm to macrophages, dendritic cells, B cells
Macrophage, Dendritice cells
Professional Phagocytes (antigen presenting cells)
Antigen presentation
T and B cells recognize antigen from invading microbes (B cell non soluble antibody)
B cell biology
source of antibodies, humoral immune response
occurs via b cell receptor, protein complex on cell surface