PPT-Barry Flashcards
(17 cards)
What is mean arterial pressure (MAP)?
The average arterial pressure during one systole
More stretch=more tense/stiff
What does high blood pressure cause?
Higher chance of fragmentation and collagen cross-linking
What are important points to remember when measuring arterial stiffness?
As mean arterial pressure increases, so does the strain on the structural elements of the aorta
What is biological ageing?
Gradual decline in physiological function and resilience of the body
Where is pressure highest in the vascular system?
Arteries
Where is pressure lowest in the vascular system?
Veins
What factors influence blood velocity from point A to point B?
Vessel diameters, blood viscosity and pressure gradients
What are two methods for measuring blood velocity?
Doppler ultrasound and flow meters
What does the central pressure wave indicate?
Arterial stiffness and the efficiency of blood flow
What does a high augmentation index signify?
Stiffer arteries and increased heart workload
How does aging affect pulse wave velocity and augmentation index?
Both increase with age due to arterial stiffness
How does arterial stiffness affect the brain?
It reduces cerebral perfusion, increasing risks of stroke and dementia
What’s a lifestyle intervention for vascular health?
Exercise
What’s a pharmacological intervention for vascular health?
Antihypertensives
How does COPD and diabetes affect AI and PWV?
COPD increases AI via chronic hypoxia
Diabetes accelerates arterial stiffening
What are the two types of blood flow profiles?
Laminar (smooth)
Turbulent (disordered)
What does the positivity index measure?
The ratio of positive pressure amplitude to the total pressure pulse
